Gülten İnan

Salbutamol or mist in acute bronchiolitis

Abstract Background: The role of bronchodilators in the treatment of bronchiolitis remains controversial.

Obesity and Its Diagnostic Methods in Turkish Children

OBJECTIVE The application of body mass index (BMI) for obesity classification in all population studies has been questioned by the scientific community. It has been found that the bioelectrical impedance analysis (BIA) is an accurate method for screening obesity. This study was conducted to evaluate the accuracies of BMI, skinfold thickness (SFT), leptin and BIA measurements in obesity classification and to find correlations between BIA and the other indicators for obesity. MATERIALS AND METHODS This case-control study included 178 children of whom 90 were in the obese group and 88 in the control group. The study measured BMI, SFT, leptin level and BIA-mediated body fat percentage (BIA BFP) in each child. RESULTS The BMIs, leptin levels, SFTs and BIA BFPs of children in the obese group were found to be higher than those in the control group (p<0.001). The measurement of BIA BFP strongly correlated with BMI, SFT and waist circumference, whereas BIA BFP measurement showed weak-moderate correlation with leptin level. CONCLUSION Bioelectrical impedance analysis was found to be an accurate measure of BFP in obesity. In addition, BIA may prevent the incorrect diagnosis of obesity as determined by BMI alone, especially in boys during the pubertal period.

Lowe syndrome with anal atresia: A possible variant of OCRL?

Oculocerebrorenal syndrome of Lowe (OCRL) is a rare, multisystem disorder characterized by congenital cataracts, mental retardation, hypotonia and renal tubular abnormalities. Enophthalmos, buphthalmos, glaucoma, miotic pupils, dental cysts, prominent forehead, protruding ears, cryptorchidism, and deafness are other clinical findings. 1,2 The OCRL syndrome is transmitted as an X-linked recessive trait. This disease is caused by mutations in the OCRL1 gene located on chromosome Xp25–26, such as premature terminations and deletions. The gene ( OCRL1 ) responsible for OCRL has been positionally cloned and shown to encode a phosphatidylinositol 4–5-bisphosphate (PtdIns[4,5]P2) 5phosphatase. 3,4 Ocular manifestations of OCRL are congenital cataracts, glaucoma, and posterior lentiglobus. Female carriers are reported to have fine peripheral cortical punctate lens opacities. 5 Initially, the renal abnormalities are like those of Fanconi syndrome but later, the glomerular filtration rate is impaired. Amino-aciduria, proteinuria, intermittent glucosuria, diminished tubular phosphate and potassium reabsorption, and proximal renal tubular acidosis are common. 2

Anne ve kord serumunda çinko ve bakır düzeyleri Orijinal Araştırma

Zinc and copper are trace elements involved in many metabolic processes and enzyme systems The aim of this study was to determine plasma zinc and copper concentrations in paired samples of maternal and umbilical cord blood from 45 mothers at delivery looking for an association between trace element levels and mother’s age and birth weight Zinc and copper concentrations were determined by atomic absorption spectroscopy Mean zinc concentrations in newborns were statistically higher than those in mothers p=0 001 In contrast; mean copper concentration in newborns were statistically lower than those in mothers p lt;0 001 There were no correlations between maternal age and plasma zinc and copper concentrations of neonates r=0 149 r=0 175 respectively No correlations were found between maternal plasma zinc and copper concentration and birth weight of neonates r=0 2 r= 0 175 respectively Key words: zinc copper newborn