Gun Wook Kim

Ear Keloids as a Primary Candidate for the Application of Mitomycin C after Shave Excision: In Vivo and In Vitro Study

BACKGROUND Although many methods have been developed to treat ear keloids, new therapeutic options are still needed. OBJECTIVE To determine the effects of topical mitomycin C (MC) on shave‐removed wounds and fibroblasts of ear keloids. METHODS Fourteen ear keloids in 12 patients were shaved, and MC (1 mg/mL) was applied to the resected bed for 5 minutes. The application was repeated 3 weeks later. All patients were assessed 2, 4, and 6 months after the procedure to evaluate the cosmetic results, recurrence, and postsurgical complications. An in vitro study to determine the effects of MC on fibroblasts of the excised keloids was conducted using the 3‐(4,5‐dimethylthiazol‐2‐yl)‐2,5‐diphenyltetrazolium bromide (MTT) assay, the measurement of total cell counts, and immunoassay of DNA synthesis. RESULTS Only one recurrence occurred (on the ear helix), and the patients were satisfied with the cosmetic outcomes. The results of the MTT assay, total cell counts, and DNA synthesis immunoassay confirmed the suppressive effects of MC on the keloid fibroblasts. CONCLUSION The application of topical MC to the resected bed of shave‐removed ear keloids was successful in preventing recurrences and providing an acceptable cosmetic outcome. The authors have indicated no significant interest with commercial supporters.

Dermatoses of the Glans Penis in Korea: A 10-Year Single Center Experience

Background A variety of infectious, inflammatory, and neoplastic dermatoses can develop on the glans penis, and definitive diagnosis in such cases may be difficult owing to their non-specific symptoms and clinical appearance. Furthermore, data on dermatoses of the glans penis in Korea are limited. Objective In the present study, we aimed to determine the prevalence of dermatoses of the glans penis in Korea and provide clinical data to assist in making an accurate diagnosis. Methods We retrospectively reviewed the medical records, clinical photographs, and histologic slides of 65 patients with dermatoses of the glans penis that visited the Pusan National University Hospital between January 2004 and August 2013. Results Twenty-six types of dermatoses were identified: inflammatory dermatosis was the most common (38/65, 58.5%), followed by infectious (13/65, 20.0%), neoplastic (10/65, 15.4%), and other dermatoses (4/65, 6.2%). The most common dermatosis of the glans penis was seborrheic dermatitis, followed by lichen planus, herpes progenitalis, condyloma accuminatum, erythroplasia of Queyrat, Zoons balanitis, and psoriasis. In the topographic analysis, the most common type of dermatosis was dermatoses that localized to the glans penis (39/65, 60.0%), followed by dermatoses involving the extra-genitalia and glans penis (22/65, 33.9%), and the genitalia (glans penis plus other genital areas) (4/65, 6.2%). Conclusion This study shows the usefulness of a topographic approach in the diagnosis of dermatoses of the glans penis in Korea. The findings could be used as baseline data for establishing an accurate diagnosis in Koreans.

Hypopigmented Mycosis Fungoides Treated with 308 nm Excimer Laser

Vol. 30, No. 1, 2018 93 Received September 20, 2016, Revised November 28, 2016, Accepted for publication December 22, 2016 Corresponding author: Moon-Bum Kim, Department of Dermatology, Pusan National University Hospital, 179 Gudeok-ro, Seo-gu, Busan 49241, Korea. Tel: 82-51-240-7338, Fax: 82-51-245-9467, E-mail: drkmp@hanmail.net This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/ licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. Copyright

A Unique Cutaneous Presentation of Breast Cancer: A Red Apple Stuck in the Breast

Vol. 28, No. 4, 2016 499 Received June 11, 2015, Revised July 15, 2015, Accepted for publication July 20, 2015 Corresponding author: Margaret Song, Department of Dermatology, Pusan National University Hospital, 179 Gudeok-ro, Seo-gu, Busan 49241, Korea. Tel: 82-51-240-7337, Fax: 82-51-245-9467, E-mail: smargie@ hanmail.net This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/ licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. Copyright

The Usefulness of Dermoscopy for Detection of Subungual White Foreign Bodies.

Dear Editor: Dermoscopy is a noninvasive and extremely useful diagnostic tool for a variety of skin diseases1. A few reports have documented that dermoscopy is also useful for the diagnosis of some zoonotic infestations including scabies and spider spines2,3. In the latter, dermoscopic findings allow the identification of spider spines clinically mimicking scabies. Here, we report a case of the successful identification and removal of a fish bone under the fingernail with the aid of dermoscopy. A 51-year-old woman presented with a 7-day history of pain in the right thumb. She had trimmed a black rockfish caught by her husband, and felt pain afterwards. When she came to our department after failing to remove the bone herself, it was difficult to find the fish bone with the naked eye (Fig. 1A). However, we were able to find a linear foreign body embedded under the nail plate using dermoscopy (Fig. 1B). The foreign body was easily removed using fine forceps. Fig. 1 (A) It was difficult to locate the foreign body with the naked eye. (B) Dermoscopic findings revealed the foreign body to be compatible with a fish bone spine and focal abscess pocket. Having the fingers pricked by a fish bone or thorn is not uncommon. Sometimes the removal of these foreign bodies can be difficult, and persistently disabling secondary infections can occur in cases of residual fragments4. However, it is often difficult to detect subungual white foreign bodies like fish bones and white hairs with the naked eye. Imaging approaches including routine X-ray, computed tomography, and magnetic resonance imaging can be helpful, but seem too extreme considering their expense and limited availability5. Using dermoscopy, we were able to identify the exact location of the colorless foreign body under the nail plate and remove it easily. In conclusion, dermoscopy can be a useful diagnostic tool for the detection of white foreign bodies such as fish bones in the subungual space.