Gwen Tatsuno | Researchain

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Publication

Featured researches published by Gwen Tatsuno.

Nature | 1999

Purification and cloning of amyloid precursor protein beta-secretase from human brain.

Sukanto Sinha; John P. Anderson; Robin Barbour; Guriqbal S. Basi; Russell J. Caccavello; David P. Davis; Minhtam Doan; Harry F. Dovey; Normand Frigon; Jin Hong; Kirsten L. Jacobson-Croak; Nancy Jewett; Pamela S. Keim; Jeroen Knops; Ivan Lieberburg; Michael Power; Hua Tan; Gwen Tatsuno; Jay Tung; Dale Schenk; Peter Seubert; Susanna Suomensaari; Shuwen Wang; Donald A. Walker; Jun Zhao; Lisa McConlogue; Varghese John

The Journal of Neuroscience | 2000

High-Level Neuronal Expression of Aβ1–42 in Wild-Type Human Amyloid Protein Precursor Transgenic Mice: Synaptotoxicity without Plaque Formation

Lennart Mucke; Eliezer Masliah; Gui-Qiu Yu; Margaret Mallory; Edward Rockenstein; Gwen Tatsuno; Kang Hu; Dora Kholodenko; Kelly Johnson-Wood; Lisa McConlogue

Proceedings of the National Academy of Sciences of the United States of America | 1999

Plaque-independent disruption of neural circuits in Alzheimer's disease mouse models.

Albert Y. Hsia; Eliezer Masliah; Lisa McConlogue; Gui-Qiu Yu; Gwen Tatsuno; Kang Hu; Dora Kholodenko; Robert C. Malenka; Roger A. Nicoll; Lennart Mucke

Human Molecular Genetics | 2001

BACE knockout mice are healthy despite lacking the primary β-secretase activity in brain: implications for Alzheimer’s disease therapeutics

Steven L. Roberds; John Anderson; Guriqbal Basi; Michael J. Bienkowski; Daniel G. Branstetter; Karen S. Chen; Stephen B. Freedman; Normand Frigon; Dora Games; Kang Hu; Kelly Johnson-Wood; Karl Kappenman; Thomas T. Kawabe; Ismail Kola; Ralf Kuehn; Michael Lee; Weiqun Liu; Ruth Motter; Nanette F. Nichols; Michael Power; David W. Robertson; Dale Schenk; Michael Schoor; George M. Shopp; Mary E. Shuck; Sukanto Sinha; Kjell A. Svensson; Gwen Tatsuno; Hartmut Tintrup; John Wijsman

Archive | 2005

β-secretase enzyme compositions and methods

John P. Anderson; Guriqbal S. Basi; Minh Tam Doan; Normand Frigon; Varghese John; Michael Power; Sukanto Sinha; Gwen Tatsuno; Jay Tung; Shuwen Wang; Lisa Mcconlogue

Archive | 2000

b-secretase inhibitor

John P. Anderson; Guriqbal S. Basi; Minh Tam Doane; Normand Frigon; Varghese John; Michael Power; Sukanto Sinha; Gwen Tatsuno; Jay Tung; Shuwen Wang; Lisa Mcconlogue

Neurobiology of Aging | 2000

Functional analysis of beta-secretase using mutagenesis and structural homology modeling

Lisa McConlogue; David A. Agard; Nobuyuki Ota; Gwen Tatsuno

Archive | 2000

HUMAN β-SECRETASE ENZYME, INHIBITORS AND THEIR COMPOSITIONS AND USES

John P. Anderson; Guriqbal S. Basi; Minh Tam Doane; Normand Frigon; Varghese John; Michael Power; Sukanto Sinha; Gwen Tatsuno; Jay Tung; Shuwen Wang; Lisa Mcconlogue

Neurobiology of Aging | 2004

P4-183 Molecular determinants of substrate recognition by the Alzheimer amyloid peptide generating protease, β-secretase (BACE)

John P. Anderson; Pamela S. Keim; Kirsten L. Jacobson-Croak; Guriqbal S. Basi; Tamie J. Chilcote; Russell J. Caccavello; Minhtam Doan; Norman Frigon; Kang Hu; Varghese John; Lisa McConlogue; Susanna Suomensaari; Gwen Tatsuno; Donald A. Walker; Shuwen Wang; Sukanto Sinha

Archive | 2000

Menschliches beta-Secretase Enzym, Inhibitoren und ihre Zusammensetzungen und Verwendungen

John P. Anderson; Guriqbal S. Basi; Minh Tam Doane; Normand Frigon; Varghese John; Lisa Mcconlogue; Michael Power; Sukanto Sinha; Gwen Tatsuno; Jay Tung; Shuwen Wang

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