H. de Groot

Prevalence of occupational allergy to Chrysanthemum pollen in greenhouses in the Netherlands

Background: An increasing number of allergic complaints appear to have occurred among Chrysanthemum greenhouse employees. The aim of this study was to estimate the prevalence of work‐related allergic symptoms and the prevalence of sensitization to pollen of different members of the Chrysanthemum family.

Prevalence of occupational allergy to bell pepper pollen in greenhouses in the Netherlands

Background An increasing number of allergic complaints appear to have occurred among bell pepper greenhouse employees.

Sublingual immunotherapy in youngsters: adherence in a randomized clinical trial

Background Adherence is essential for effective treatment. Although several trials on the efficacy of sublingual immunotherapy (SLIT) in youngsters have been published, few contain data on medication intake.

Serum tryptase and SCORMA (SCORing MAstocytosis) Index as disease severity parameters in childhood and adult cutaneous mastocytosis

Background.u2002 Skin lesions are the predominant clinical feature of the commonest form of mastocytosis. Mastocytosis is classified according to World Health Organization criteria. Determination of the levels of mast‐cell mediators or their metabolites reflects the mast‐cell burden. The extent of cutaneous mastocytosis can be assessed clinically using a scoring system (SCORing MAstocytosis; SCORMA Index) that we have developed.

Original article: Nasal nitric oxide: longitudinal reproducibility and the effects of a nasal allergen challenge in patients with allergic rhinitis

Background:u2002 Exhaled nitric oxide (eNO) is a validated noninvasive marker of airway inflammation in asthma. In patients with allergic rhinitis (AR), increased levels of nasal nitric oxide (nNO) have also been measured. However, the applicability of nNO as a marker of upper airway inflammation awaits validation.

Sensitization to lupine flour : is it clinically relevant?

Background Lupinus angustifolius (blue lupine) is used for human and animal consumption. Currently, the lupine content in bread varies from 0% to 10% and from 0.5% to 3% in pastry. Although lupine flour is present in many products, anaphylaxis on lupine flour is rarely seen.

Allergy to bumblebee venom. III. Immunotherapy follow‐up study (safety and efficacy) in patients with occupational bumblebee‐venom anaphylaxis

Background: The objective was to investigate whether venom immunotherapy with bumblebee venom (BBV) is safe and effective.

Primary sensitization to sweet bell pepper pollen in greenhouse workers with occupational allergy

Background In a previous investigation, a high prevalence of allergy to sweet bell pepper pollen was found among exposed horticulture workers. Allergy to plant‐derived food is often the consequence of primary sensitization to common pollen allergens.

sIgE Ana o 1, 2 and 3 accurately distinguish tolerant from allergic children sensitized to cashew nuts.

The double‐blind, placebo‐controlled food challenge test (DBPCFC) is the gold standard in cashew nut allergy. This test is costly, time consuming and not without side effects. Analysis of IgE reactivity to cashew nut components may reduce the need for food challenge tests.

No difference in health-related quality of life, after a food challenge with cashew nut in children participating in a clinical trial

Previous studies showed that health‐related quality of life (HRQL) significantly improved after the food challenge, with greater improvements in HRQL after a negative outcome than after a positive outcome. It is currently unknown whether this also occurs in patients undergoing DBPCFCs with cashew nut in the context of a clinical trial.