H. Fang

Cascade arylalkylation of activated alkenes: synthesis of chloro- and cyano-containing oxindoles.

The general method for the oxidative cyclization of arylacrylamides with dichloromethane or acetonitrile has been developed. The reactions described provide novel access to chloro- and cyano-containing oxindoles in good to moderate yields that allow the direct formation of a C-C bond and the construction of an oxindole ring in one reaction. The use of a cheap and easily prepared Mn(OAc)3 represents an added advantage of this method.

Synthesis, characteristics and biological activity of pentacoordinated spirophosphoranes derived from amino acids.

Summary.The reactions of phosphorus trichloride with various amino acids afford the pentacoordinated spirophosphoranes. The reaction procedures were traced by 31P NMR spectra techniques. A new crystal structure of alanine derivative was characterized, which is a slightly distorted TBP structure. Besides, this kind of spirophosphoranes are potent inhibitors to tyrosinase.

(3S,8S)-3,8-Di­methyl-1,6-dioxa-4,9-di­aza-5λ5-phospha­spiro­[4.4]­nonane-2,7-dione

In the the title compound, C6H11N2O4P, the P atom and the attached H atom lie on a crystallographic twofold axis. The molxadecule adopts a slightly distorted trigonal bipyramidal structure. The crystal structure involves intermolecular N—H⋯O hydrogen bonds.

(3S)‐4‐Phenyl‐3‐(phenylaminooxy)butan‐2‐one. Corrigendum

In the paper by Yang, Fang, Zheng & Weng [Acta Cryst. (2007), E63, o3568], the correspondence author is marked incorrectly. The correct correspondence author and e-mail address are given here.

(3S)-4-Phenyl-3-(phenylaminooxy)butan-2-one

The title compound, C16H17NO2, is an interxadmediate in our work on chiral acylxadoins. The crystal structure shows that molxadecules are linked by N—H⋯·O hydrogen bonds.

N-{ 3 '-formyl-2,2 '-bis(methoxymethoxy) biphenyl-3-yl methyl} formamide

The title compound, C19H21NO6, was obtained by ortho-lithiaxadtion of 2,2′-bisxad(methoxyxadmethxadoxy)biphenyl, followed by quenching with N,N-dimethylxadformaldehyde. The molxadecular packing is stabilized by van der Waals forces.

Diphenyl (hydroxyphenylmethyl)phosphonate

The title compound, C19H17O4P, was obtained as colorless block-shaped crystals by the reaction of diphenyl phosphite and benzaldehyde. The crystal structure is stabilized by strong interxadmolecular O—H⋯O hydrogen bonds.

Dimethoxyphosphoryl)(phenyl)methyl benzoate

The title compound, C16H17O5P, was obtained by the reaction of benzoyl chloride and dimethyl (hydroxyxadphenylxadmethxadyl)xadphosxadphonxadate. The molxadecular packing is stabilized by van der Waals forces.

(S)-3- 4-(benzyloxy)phenyl -2-hydroxy-propanoic acid

The title compound, C16H16O4, has been obtained by the reaction of O-benzylxadated l-tyrosine with sodium nitrite as colorless blocks. The packing of the title compound exhibits two independent hydrogen bonds involving the hydrxadoxy and carboxylic groups, giving rise to an infinite ladder parallel to the b axis.

Dimethyl phenyl(pyridine-4-carboxamido)-methyl phosphonate

In the crystal structure, the title compound, C15H17N2O4P, exists as a centrosymmetric dimer containing N—H⋯O=P hydrogen bonds. The amino N atom interacts with the doubly bonded phosphoxadryl O atom.