H. N. Cole

Excretion of Bismuth in Series of Clinical Bismuth Treatments

Conclusions General Conclusions: 1. The resemblances between these bismuth compounds appear more impressive than the differences; the salicylate stands apart, with a much slower but more persistent absorption and excretion. 2. The excretion and absorption velocity is in the order of: Watery solutions (A) > oil solutions (D) > tartrate oil (B) > salicylate oil (C). 3. The peak excretion and the total (cumulative) excretion (within 3 weeks) run fairly parallel in the general order: 4. The percentage excretion is nearly uniform for practically all, 15 to 25% within 3 weeks; it is much lower for salicylate-oil—2.9% (but here the excretion is very persistent, and longer after-period would give relatively higher percentage). The percentage excretion is materially above the average with single oil-solutions (D)—39 and 45%. The fccal excretion, so far as studied, seems to be about a tenth of the urinary excretion and fairly parallel to it.