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Featured researches published by H. Tan.


Ultrasound in Obstetrics & Gynecology | 2018

EP19.09: Ultrasound evaluation of mesonephric paraovarian cyst: findings and differential diagnosis: Electronic Poster Abstracts

Y. Tee; S. Lee; Winson Jianhong Tan; H. Tan

solid nodular components and papillary projections is suspicious for ovarian malignancy. Suggested histological correlation and correlation with biochemical tumour markers. Peritoneal nodularity in the anterior aspect of the right upper quadrant and in the right posterior perirenal space is suspicious for peritoneal metastases. Bilateral mild minimal hydronephrosis and proximal hydroureter are probably due to compression of distal ureters by the large pelvic mass. Biochemical markers: Ca125 112, CEA normal, Ca 19-9 normal. She was subsequently listed for elective THBSO F/S kiv omentectomy PLND PAND, kiv bowel resection stoma. Operative findings: left ovarian mass 22 x 15 cm, multiloculated solid cystic; adherent to posterior surface of uterus, POD; rectosigmoid and left pelvic side wall. Left tube wrapped upon the ovarian tumour, right tube and ovary normal. uterus was atrophic, posterior surface densely adherent to left ovarian tumour, deposits on rectum and sigmoid -1-1.5cm. Multiple deposits and right paracolic gutter, deposits on peritoneum covering kidneys. Frozen section; Adenocarcinoma with tubulocystic and papillary architecture lined by atypical clear cells favour clear cell carcinoma. Histopathological findings: bilateral ovarian clear cell adenocarcinoma.


Ultrasound in Obstetrics & Gynecology | 2018

EP15.20: Ultrasound evaluation of complex endometrial disorders: case report: Electronic Poster Abstracts

L. Ng; S. Lee; L. Tan; H. Tan

Results: We analysed 160 patients with suspicion of endometrial polyp. We diagnosed 107 polyps in our study group. We also analysed the diagnostic parameters for ultrasonography in diagnosing endometrial polyps: sensitivity, specificity, negative predictive value, positive predictive value and accuracy were as follows: 48.6, 80.2, 65.6, 66.7, 66, p-value was<0.001. Conclusions: Transvaginal probes give very good images which have good specificity in diagnosing endometrial polyps.


Ultrasound in Obstetrics & Gynecology | 2018

EP01.08: Asherman's syndrome in pregnancy: case reports: Electronic Poster Abstracts

S. Lee; S. Yu; Winson Jianhong Tan; H. Tan

Pregnant D: 43-year old, 16th pregnancy, 2 deliveries, in 2009 operative delivery, one late miscarriage on the 20th week and 12 medical abortions without complications. Medical conclusion about full or partial adherent of placenta has been done in the 1st trimester, at 12/1 weeks, and it was confirmed by all US, the growth of features of vein bulge in pelvis, uterus and cervix. CS has been performed at the 37th-38th weeks of gestation, and the new born delivered with weight of 3.030 grams and height of 55 cm. During the operation, placenta percreta was identified: a part of chorionic villi was embedded into myometrium, CS scar and the back wall of a bladder. A radical operation was performed hysterectomy without adnexas as well as a plastic surgery of the bladder. The usage of two-dimensional ultrasound in combination with different variations of colour Doppler allows to assume the adherent placenta in the 1st trimester of pregnancy and it also contributes to prevention of serious complications in pregnancy and maternal mortality.


Ultrasound in Obstetrics & Gynecology | 2018

EP10.21: Fetal aortic and pulmonary artery diameters in normal pregnancy: Electronic Poster Abstracts

Wai Keong Wong; Stephanie Fook-Chong; S. Lee; Winson Jianhong Tan; L. Tan; H. Tan

Introduction Abnormal diameters of the great vessels are known to be markers of congenital heart diseases, e.g. tetralogy of Fallot, truncus arteriosus and coarctation of aorta. In order to improve prenatal detection of these forms of congenital heart defects, we include the great vessels diameter in the routine fetal ultrasound examination. Objective To construct centile nomograms for aortic and pulmonary artery diameters in the second and third trimesters. Method The patients recruited all fulfilled the following criteria : (1) known last menstrual period with regular cycles, (2) no fetal anomalies, (3) no pregnancy complications, (4) live birth at term, (5) birth weight above the 5th and below the 95th centile for gestation. Pulmonary and aortic diameters were measured by transabdominal ultrasound on long-axis views of the great vessels. Measurements of the great vessels were taken at the level just above the aortic and pulmonary valves during ventricular systole. The relationship between the mean of each measurement and gestational age was modelled by a fractional polynomial regression. Results 150 cases were recruited. Diameters range from 2.1mm (aortic) and 2.5mm (pulmonary artery) at 18 weeks of gestation to 6.5mm ( aortic) and 9.7mm ( pulmonary artery ) at 39 weeks of gestation. Conclusion We conclude that the diameter of the great vessels grows linearly with gestational age in normal fetuses. The procedure for selecting the best fitting model was based on minimising the deviance as in the appendix of Royston and Wright (1998). Similarly a standard deviation (SD) curve for each measurement was estimated by regressing the ‘scale absolute residuals’ on gestational age, again using fractional polynomial. The 5th and 95th percentile of the measurement at each gestational age is given by means ± 1.645 SD. All analyses and graphics were made using software STATA version 13. 0 1 2 3 4 5 6 7 8


Head and Neck-journal for The Sciences and Specialties of The Head and Neck | 2018

Pigmented epithelioid melanocytoma with nodal melanosis: A rare cause of cystic cervical lymphadenopathy

H. Tan; Lianne Ai Ling Lee; Felix Paulus; Choon Chieh Tan

Head and neck malignancies often present as firm, solid nodal masses. However, malignancies arising from Waldeyers Ring may give rise to cystic lymph nodes.


Journal of Gastrointestinal Cancer | 2017

Epidermal Inclusion Cyst in an Intra-pancreatic Accessory Spleen: a Differential Diagnosis for Pancreatic Cystic Neoplasms and Review of the Literature

H. Tan; Wei Li Neo; Ser Yee Lee; Brian K. P. Goh; Juinn Huar Kam

The incidence of accessory spleen is approximately 10% in autopsy findings, with the most frequent location being at the tail of the pancreas [1, 2]. Epidermoid cysts arising from ectopic spleen tissue in the tail of the pancreas are a benign and extremely rare pathology. At present, less than 50 cases were being reported in the English literature. This entity is not well characterized; we aim to shed some light in this rare entity with a brief literature review and our experience in two cases.


Journal of Gastrointestinal Cancer | 2017

Rectal Cancer Surveillance—Recurrence Patterns and Survival Outcomes from a Cohort Followed up Beyond 10 Years

Winson Jianhong Tan; H. Tan; Sreemanee Raaj Dorajoo; Fung Joon Foo; Choong Leong Tang; Min Hoe Chew

AimThe intensity and duration of surveillance for rectal cancer after surgical resection remain contentious. We evaluated the pattern of recurrences in a rectal cancer cohort followed up beyond 10xa0years.MethodsAn analysis was performed on a retrospective database of 326 patients with rectal cancer who underwent curative surgical resection from 1999 to 2007. The above study duration was chosen to ensure at least 10xa0years of follow-up. Data on patient demographics, peri-operative details, and follow-up outcomes were extracted from the database. The pattern of recurrences and investigative modality that detected recurrences was identified. Patients were followed up until either year 2016 or the day of their demise.ResultsTwo hundred seventeen patients (66.6%) were male and 109 patients (33.3%) female. Median age was 64xa0years old. Close to a third of the patients received adjuvant therapy (34%). Among the 326 patients studied, 29.8% of (97/326) patients developed recurrence. 7.7% (25/326) had loco-regional recurrence while 22.1% (72/326) had distant metastasis. Median time to recurrence was 16xa0months (4–83) and 18xa0months (3–81), respectively. Computed tomography scan was the best modality to detect both loco-regional and distant recurrences (48% in loco-regional and 41.7% in distant metastasis). The most common site of distant metastasis is the lung (34.7%). The salvage rate for loco-regional and distant recurrences was 52 and 12.5%, respectively.ConclusionThe predominant pattern of recurrence in rectal cancer is distant disease. Surveillance regimes may need to be altered to increase early detection of distant metastases.


Ultrasound in Obstetrics & Gynecology | 2012

P13.07: Evaluation of fetal corpus callosum using two‐dimensional and three‐dimensional ultrasonography

Wai Keong Wong; S. Lee; Winson Jianhong Tan; H. Tan

3D US did not markedly improve information from 2D US, however it allowed fast and easy CNS evaluation in 3 orthogonal planes. Associated anomalies were found in none case of septal agenesis and in almost all ACC cases. Conclusions: There was substantial disagreement in diagnosis between referral US and our combined imaging, while both MRI and US performed similar in our hands. Thus if to compare MR and US, they should be performed by a specialized operator. We found high incidence of associated anomalies in ACC case with, many of them being diagnosed only by MRI. Therefore we would recommend MRI to be performed in all midline brain anomaly cases. Supported by the grant MZOFNM2005.


Ultrasound in Obstetrics & Gynecology | 2018

EP17.08: Evaluate of the LSCS scars in the uterus using 2-dimensional (2D) and 3-dimensional (3D) ultrasound: Electronic Poster Abstracts

Yan Wang; S. Lee; L. Tan; Winson Jianhong Tan; H. Tan


Ultrasound in Obstetrics & Gynecology | 2018

EP05.15: Sonographic reference range of fetal thymus size for the second and third trimester fetuses: Electronic Poster Abstracts

J. Ho; Stephanie Fook-Chong; S. Lee; L. Tan; Winson Jianhong Tan; H. Tan

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S. Lee

Singapore General Hospital

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L. Tan

Singapore General Hospital

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Ser Yee Lee

Singapore General Hospital

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Wai Keong Wong

Singapore General Hospital

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Brian K. P. Goh

Singapore General Hospital

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Choong Leong Tang

Singapore General Hospital

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Fung Joon Foo

Singapore General Hospital

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J. Ho

Singapore General Hospital

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