Hae Jun Song

Iatrogenic Mycobacterium abscessus infection associated with acupuncture: clinical manifestations and its treatment

Background  Mycobacterial infections transmitted by acupuncture are an emerging problem. There have been two reports of mycobacterial infections complicating acupuncture in the English literature.

A study of the solar effect on actinic keratoses by quantification of elastic fibres using an image analysis system

It is widely accepted that elastotic changes of the skin are primarily an indicator of cumulative sun exposure of the dermis and are a characteristic finding of actinic keratoses. To date, there have been few reports that measure the amount of elastic tissue objectively and quantitatively, especially in actinic keratoses. The computerized image analysis method has proved useful recently in determining the area of elastic fibres. Using this method, we objectively quantified the elastotic tissue in actinic keratoses and evaluated the relationship between the degree of dermal elastosis, epidermal atypia and histological types of actinic keratoses. Of the 28 actinic keratoses studied, the average percentage area of the elastic fibre was 40.48 +/- 14.48 (mean +/- SD) percentile. There was a 3.65-fold increase in the amount of elastic fibre in actinic keratoses compared with that of seborrhoeic keratoses occurring on the face (p < 0.00001). In addition, the more severe the atypia, the greater the area of elastic fibres in a representative section of the dermis. In conclusion, we observed that on quantitative assessment of elastic tissue in actinic keratoses, the percentage area of the elastic fibres in a representative section of the dermis ranges from 34.86 to 46.11%. This result may provide information for use in histological diagnosis of actinic keratoses and evidence for the possible role of sunlight in the pathogenesis of actinic keratosis.

Updated view on epidemiology and clinical aspects of pilomatricoma in adults

Clinically, pilomatricoma offers potential for a wide spectrum of differential diagnoses. It typically occurs in pediatric patients with the head being the most common location. A second peak of clinical presentation occurs in adults at age 50–65 years, suggesting a bimodal pattern of occurrence.

Plantar leukocytoclastic vasculitis with detection of herpes simplex virus type 2 by PCR assay.

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Asymmetrical periflexural exanthem of childhood with concurrence of molluscum contagiosum infection

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Disseminated cryptococcosis presenting as cellulitis

Sir, Cryptococcosis is commonly associated with immunosuppression and the primary site of infection is usually lungs; however, a cutaneous form of infection is seen in about 6–10% of patients. The cutaneous lesions develop as a result of dissemination or rarely, through direct inoculation. Major cutaneous findings include umbilicated or acneiform papules, pustules progressing to crusted plaques, or nodules.1,2 Cryptococcal cellulitis is not commonly considered as a differential diagnosis in a patient without acquired immunodeficiency syndrome (AIDS) or history of undergoing organ transplant. We report cryptococcal infection presenting as cellulitis in a patient with renal failure, undergoing oral steroid therapy.

Extramammary Paget`s Disease of the Penis and Scrotum with a Renal Cell Carcinoma

Extramammary Pagets disease is a rare cutaneous malignancy and frequently associated with an underlying adnexal carcinoma and perhaps with underlying internal ma1iycy. In our case, genita1 Pagets disease was followed by the discovery of renal cell carcinoma. We report a rare case of extramammary pagets disease of the penis and scrotum which associated with a renal cell carcinoma. (Ann Dermatol 11(1) 51~54,1999).