Hae Kwang Lee

Investigation of biochemical changes in skin layers by NMR microscopy

Background/aims: Biochemical changes occurring in epidermis are hardly visible on a conventionally acquired magnetic resonance image. Objectives of the present study were to noninvasively visualize the biochemical changes in skin layers and to investigate the feasibility of dermal NMR microscopy.

Metabolomic analysis of amino acids and lipids in human hair altered by dyeing, perming and bleaching

tine. The quantitative real-time RT-PCR in the presented setting represents accurate and reproducible mRNA gene quantification and might improve current staging procedures by stratifying the patients to subpopulations with favourable and unfavourable prognosis. Acknowledgements This work was supported by IGA NT 14440-3/2013 Czech Ministry of Health grant. All authors substantially contributed to the manuscript. Petr Arenberger and Monika Arenbergerova designed the research study, performed the research and wrote the manuscript; Alena Fialova and Spyridon Gkalpakiotis performed the research and analysed the data; and Andrea Pavlikova performed the research. The submitted and final version of the manuscript was critically revised and approved by the authors. Conflict of interest The authors have declared no conflicting interests. Supporting Information

A quantitative evaluation method using processed optical images and analysis of age-dependent changes on nasolabial lines

Nasolabial lines (NL) and wrinkles of the face are major features of aging. Wrinkles have been studied widely by morphological methods using 3‐dimensional (3D) photographic analysis instrument, but NL were evaluated by visual scoring usually. To evaluate NL quantitatively, another method is needed. This study is purposed to find out quantitative method for evaluation of NL.

Comparison of skin properties in individuals living in cities at two different altitudes: an investigation of the environmental effect on skin

Skin properties vary depending on exogenous factors. Various studies have been used for comparing skin properties between cities for studying environment influence on skin properties. However, for comparison of skin properties between cities, various environmental factors have to be considered.

Effect of Cosmetics Contained Isotonic Water Mimicked Body Fluid on Cell Activities and Skin

생체수는 링거액, 인공관절액, 세포 배양 등 다양한 분야에서 연구되어 왔다. 이는 생체수가 체온을 조절하는데 결정적인 역할을 하고, 생체 내 다양한 대사 과정에서 용매로 사용되며, 삼투압이나 능동적 섭취를 통한 혈액 또는 림프액을 통해 세포에서 세포로 전달되는 미네랄, 에너지원, 호르몬, 시그널과 약물의 전달 물질로 이용되기 때문이다. 세포외 지질과 자연보습성분(natural moisturizing factor, NMF)을 함유하는 각질층은 외부의 수분을 끌어들여 내부 수화에 이용하며, 이러한 과정들은 피부 장벽 기능과의 연관성이 높다. 본 연구에서는 피부 장벽 기능을 강화하는 아미노산, 펩타이드, 단당류를 포함한 생체모사수(Cell Bio Fluid SyncTM)를 인체 피부에 처리하여 세포활성을 관찰하고, 생체 모사수를 함유한 제품을 피부에 도포하여 인체피부 개선 효과를 연구 하였다. 피부 세포 활성을 보기 위해 각질세포인 HaCaT 세포를 이용하였고, 에너지 고갈상태로 만들기 위해 3시간 동안 PBS에 전 처리한 후 이후 세포 배양액인 DMEM 및 등장액인 PBS, 생체 모사수(Cell Bio Fluid

Comparison of stratum corneum thickness between two proposed methods of calculation using Raman spectroscopic depth profiling of skin water content

Sync^{TM}

A method of evaluating facial pores using optical 2D images and analysis of age-dependent changes in facial pores in Koreans

)에 각각 3시간 처리하였다. 이후 MTT assay와 이미지 분석을 수행하였다. 인체의 피부 개선 효능을 위한 임상 연구에 21명의 여성이 참여하였다. 생체 모사수를 함유한 제품을 1주일간 안면에 도포하였고, 수분량, 피부결, 밝기 그리고 피부 균일도를 측정하였다. 모든 측정은 피험자가 세안 후 항온항습조건(

A new technique for evaluating heel xerosis grade and the effects of moisturizer on heel skin dryness

22{\pm}2^{\circ}C

Permanent Chemotherapy‐Induced Alopecia in Patients with Breast Cancer: A 3‐Year Prospective Cohort Study

,

The ginsenosides of Panax ginseng promote hair growth via similar mechanism of minoxidil

50{\pm}5%