Halil Murat Şen

Evaluation of Platelet Distribution Width and Mean Platelet Volume in Patients With Carotid Artery Stenosis

Platelets contribute to the pathogenesis of atherosclerosis. Platelet activation has been linked with increased mean platelet volume (MPV) and platelet distribution width (PDW). We investigated the association between PDW, MPW, and the degree of carotid artery stenosis (CS). Patients (n = 229) were divided into 3 groups according to the North American Symptomatic Carotid Endarterectomy Trial criteria. Demographic and clinical features were collected retrospectively. Correlation analysis showed a positive association between PDW and the degree of CS. However, there was no significant correlation between CS and MPV. Moreover, we observed that PDW and low-density lipoprotein cholesterol were independent predictors of the degree of CS. This study showed that PDW, not MPV, is related to the degree of CS. Platelet distribution width could be a useful biomarker for CS. Whether targeting PDW will be of clinical benefit remains to be established.

Sleep disturbance among women with chronic pelvic pain

To investigate the effect of chronic pelvic pain (CPP), a debilitating condition, on sleep quality.

Serebellopontin açı yerleşimli ve astrositomu taklit eden bir medullablastom olgusu

Medulloblastom en sik gorulen malign ve kontrol edilemeyen cocukluk cagi beyin tumorudur. Tumor her yastaki hastalarda gorulur, 3 ve 9 yas arasindaki cocuklarda bir zirveye ulasir ve ayni zamanda cocukluk caginda en sik gorulen kotu huylu beyincik tumorudur. Yetiskinlerde beyin tumorlerinin %1 ile %2sini olusturur. Tanim olarak, medulloblastomlar genellikle posterior fossa, bazen pineal bolge veya pontoserebellar bolgeden kaynaklanan tumorler histolojik olarak benzer sekilde siniflandirilir. Bu hastaligin geleneksel tedavisi, posterior fossa cerrahisi, ardindan posterior fossaya yuksek doz olmak kaydiyla kraniyospinal radyasyon tedavisi seklindedir. Bu yazida, 13 yasinda bir kiz cocugunda bas agrisi ve bas donmesi belirtileri ile ortaya cikan, astrositomu taklit eden bir posterior fossa medulloblastomu olgusunu sunuyoruz.