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Featured researches published by Handel E. Reynolds.


Seminars in Ultrasound Ct and Mri | 1996

Sonography of the breast

Valerie P. Jackson; Handel E. Reynolds; Donald R. Hawes

Quality mammography remains the primary modality used to image the breast. Sonography currently is the most useful adjunctive technique to mammography, having roles in differentiating cystic from solid masses and in guiding interventional procedures. This article reviews these and other indications for breast ultrasound studies, including evaluation of palpable masses not visible in radiographically dense breasts, masses not completely evaluable with mammography, young patients especially susceptible to radiation damage, and abscesses. Ultrasound interpretation of cysts and solid masses are discussed, as are the relative disadvantages of ultrasound as a breast cancer screening tool.


BiOS 2000 The International Symposium on Biomedical Optics | 2000

Thermoacoustic CT: imaging principles

Robert A. Kruger; William L. Kiser; Kathy D. Miller; Handel E. Reynolds; Daniel R. Reinecke; Gabe A. Kruger; Peter J. Hofacker

We have developed instrumentation for measuring the tissue- absorption properties of radio waves in the human body using thermoacoustic interactions. The imaging principles upon which this instrumentation is based are applicable to other irradiation sources, such as visible and IR. We present the imaging reconstruction methodology that we have developed for mapping radiation absorption pattern sin 3D. Both simulated and experimental data are used to illustrate imaging principles.


Annals of Plastic Surgery | 1994

Comparison of Mammography, Sonography, and Magnetic Resonance Imaging in the Detection of Silicone-Gel Breast Implant Rupture

Handel E. Reynolds; Kenneth A. Buckwalter; Valerie P. Jackson; Barbara K. Siwy; Stanley G. Alexander

Silicone-gel breast implant rupture is difficult to diagnose preoperatively. A variety of radiological methods have been used for diagnosis. This study prospectively compares film-screen mammography, high-resolution sonography, and magnetic resonance imaging in the diagnosis of implant rupture using predetermined diagnostic criteria. Thirteen patients (24 implants) underwent film-screen mammography, sonography, and magnetic resonance imaging to evaluate the integrity of their implants. All patients subsequently underwent surgical removal of the implants. Preoperatively, the integrity of each implant was rated on a three-level classification system on the basis of one modality by a reviewer who was unaware of the results of the other two modalities. The three imaging modalities achieved the following sensitivities and specificities, respectively: mammography, 69% and 82%; sonography, 54% and 64%; MRI, 69% and 55%. Even though each modality addresses some of the limitations of the others, in this group of patients, there was no clearly superior imaging tool.


Breast Journal | 1996

Large‐Gauge Core Needle Biopsy of the Breast

Handel E. Reynolds; Valerie P. Jackson; Florence M. Gin; Colleen M. Madden; Donald R. Hawes

Abstract: Large‐gauge core needle biopsy (LGCNB) of the breast is gaining acceptance as a viable alternative to surgical excision. The procedure can be performed efficiently using ultrasound or stereotactic guidance. We report our experience with 137 LGCNB performed over a 40‐month period.


Medical Imaging 2000: Ultrasonic Imaging and Signal Processing | 2000

Thermoacoustic CT scanner for breast imaging: design considerations

Robert A. Kruger; William L. Kiser; Kathy D. Miller; Handel E. Reynolds; Daniel R. Reinecke; Gabe A. Kruger; Peter J. Hofacker; R. L. Eisenhart

We have previously developed instrumentation for performing thermoacoustic computed tomography (TCT) of the human breast using 434 MHz radio waves. Recently, we have modified our original TCT scanner design in a number of important ways. We have increased the number of ultrasound detectors and decreased their size, and we have replaced our single RF wave- guide with a phased array of eight wave-guides. These modifications have led to increased spatial resolution, increased imaging field of view, and decreased scan time. Here we report the design considerations that led to these improvements.


Radiology | 1999

Benign versus Malignant Solid Breast Masses: US Differentiation

Guita Rahbar; Angela C. Sie; Gail C. Hansen; Jeffrey S. Prince; Michelle L. Melany; Handel E. Reynolds; Valerie P. Jackson; James Sayre; Lawrence W. Bassett


Radiology | 2000

Breast Cancer in Vivo: Contrast Enhancement with Thermoacoustic CT at 434 MHz—Feasibility Study

Robert A. Kruger; Kathy D. Miller; Handel E. Reynolds; William L. Kiser; Daniel R. Reinecke; Gabe A. Kruger


American Journal of Roentgenology | 1999

Stereotactic biopsy of ductal carcinoma in situ of the breast using an 11-gauge vacuum-assisted device: persistent underestimation of disease.

B Won; Handel E. Reynolds; C L Lazaridis; V P Jackson


American Journal of Roentgenology | 2000

Core needle biopsy of challenging benign breast conditions: a comprehensive literature review.

Handel E. Reynolds


American Journal of Roentgenology | 1998

Biopsy of breast microcalcifications using an 11-gauge directional vacuum-assisted device.

Handel E. Reynolds; C M Poon; R J Goulet; C L Lazaridis

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William L. Kiser

Pennsylvania State University

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Angela C. Sie

University of California

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B Won

Indiana University

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