Harry H. Mincer

Pulse granuloma of the alveolar ridge.

Six examples of pulse granulomas of the alveolar ridge are presented. The lesion consists of a foreign-body granuloma containing identifiable particles of leguminous foods. The vegetable matter is introduced through an alveolar defect, usually a postextraction socket. Simple curettage is apparently adequate treatment to effect cure.

Nerve sheath myxoma in the tongue

Abstract The myxoma of nerve sheath is a rare benign neoplasm characterized by an abundant mucoid matrix and apparently arising in the endoneurium of peripheral nerves. A case occurring in the tongue is reported.

Ultrastructure of three histologic variants of the ameloblastoma

The ultrastructural features of a follicular ameloblastoma, a cystic ameloblastoma, and a pseudoglandular ameloblastoma are examined. Although common origin from oral epithelium is evidenced by the presence of tonofilaments and desmosomes in every specimen, variations are prominent among the different tumors. Findings which indicate that differentiation toward odontogenesis may be more advanced in this neoplasm than is generally accepted include: polarization of nuclei and mitochondria, “dark” ameloblasts, autophagolysosomes, and a juxtaepithelial component which resembles early enamel or dentinal matrix. Cells similar to mucin‐secreting and eccrine elements are also present. One of the tumors contains intranuclear inclusions which resemble papovirus particles. Cyst formation in an ameloblastoma appears to result from stromal degeneration, expansion of intercellular space within epithelial islands, and breakdown of epithelial cells.

Electron microscopic changes in rat parotid and submandibular glands subsequent to total body irradiation with fast neutrons

Female Sprague-Dawley rats wre irradiated with fast neutrons to study the radiobiologic effect on the parotid and submandibular salivary glands. Cytologic alternations were seen in the parotid tissues as early as 3 hours after exposure and peaked in both parotid and submandibular glands by the fourth postradiation day. The injury was manifest as damaged and sequestered intracytoplasmic organelles appearing as pleomorphic inclusions. The two types of glandular tissue showed similar morphologic alterations. No injury to blood vessels or other radiosensitive cells could be found.

Microleakage of composite resin and glass ionomer cement restorations in retentive and nonretentive cervical cavity preparations

Ketac Fil glass ionomer cement (GIC) and Scotchbond 2 dentinal bonding agent (DBA)/Silux Plus composite resin restorations were inserted in cervical cavity preparations of extracted human teeth. After thermocycling, the specimens were invested and sectioned longitudinally and horizontally through the center of the restoration. Microleakage was evaluated as a ratio of the extent of methylene blue dye penetration at the tooth-restoration interface. Although all restorations exhibited leakage, both the GIC and bonded composite resin restorations recorded less leakage in retentive than in nonretentive cavity preparations. Composite resin restorations in nonretentive cavity preparations showed significantly more dye penetration toward the pulpal chamber than the GIC restorations. Ketac Fil GIC restorations inserted without a matrix strip exhibited less leakage than those with a matrix strip. The most desirable results were recorded with Scotchbond 2 DBA/Silux Plus composite resin restorations in retentive preparations.

Intraoral ancient neurilemoma (ancient schwannoma): Report of a case with histologic and electron microscopic studies

A case of ancient neurilemoma arising in the oral soft tissues is presented. Histologic and electron microscopic studies indicate that this tumor is, indeed, a variant of the neurilemoma and that the Schwann cell is the cell of origin. At the ultrastructural level, the bulk of the lesion is composed of numerous reduplications of basal lamina accompanying thin cytoplasmic processes and thus resembles a confluence of Verocay bodies as described in previous studies of classic neurilemomas. Heretofore unreported submicroscopic calcified spherules were observed scattered through the basal lamina material.

Juvenile pemphigus vulgaris. Report of a case.

Although pemphigus vulgaris rarely occurs in childhood, we herewith report the history of a 19-year-old patient with an apparent 4-year course of pemphigus. In this patient, as in every previously reported case of childhood pemphigus, oral lesions preceded the appearance of skin manifestations. The importance of early biopsy and adequate treatment with adrenocorticosteroids is emphasized.

Ultrastructure of sclerotic cemental masses.

Electron microscopic findings in a focus of early calcification in a case of sclerotic cemental masses of the jaws are described. The lesional cells generally resemble typical collagen-producing cells, except that many contain unusually large numbers of intracytoplasmic actinlike filaments. This and other fine structural features are reminiscent of fibroblasts involved in active tissue repair. These observations suggest that the lesion is basically reactive in its biologic nature. The most characteristic portion of the mineralized component, the rounded calcified globules, ultrastructurally resembles primary cementum.