Harry M. Goldin

Woolly-Hair Nevus: A Case Report and Study by Scanning Electron Microscopy

Abstract: Woolly‐hair is a congenital defect that produces a localized patch of lightly colored, curly scalp hair. Scanning electron microscopy of the abnormal hairs demonstrates twisting of the hair shaft and abnormal cuticle formation.

Acanthosis nigricans associated with mycosis fungoides

A case of acanthosis nigricans coexistent with mycosis fungoides, the second report in the literature of such an association, is described.

Rifampin and Exfoliative Dermatitis

Excerpt To the editor: We report a case of exfoliative dermatitis we believe was induced by rifampin. A 63-year-old Filipino man had evidence of pulmonary tuberculosis on routine chest radiographic...

Pemphigus foliaceus–like, immunologically negative dermatosis in a patient with T cell chronic lymphocytic leukemia

A 56-year-old black man developed a pemphigus foliaceus-like bullous eruption as the initial presentation of chronic T cell lymphocytic leukemia. Histologic examination disclosed superficial acantholysis consistent with pemphigus foliaceus and an infiltrate of atypical lymphoid cells in the papillary dermis. Repeated direct and indirect immunofluorescence studies yielded negative results. Acantholysis could be reproduced in vitro by incubation of normal human skin with the patients serum and plasma but not with blister fluid. In the following months, the course of the bullous eruption paralleled that of the leukemia.

Scleromyxedema with Corneal Deposits

Scleromyxedema (Arndt-Gottron syndrome) is a rare cutaneous disease in which hyaluronic acid is deposited in the dermis. The authors describe a patient with scleromyxedema and corneal deposits. A corneal biopsy demonstrated hyaluronic acid deposition in the corneal stroma and amyloid P component in Bowmans membrane. This is the first report of scleromyxedema involving the cornea. It is also the first report of amyloid P component deposition in the cornea occurring independent of corneal amyloid deposits.