Haruyuki Yamada

Pachymeningoencephalitis: case report.

Hypertrophic cranial pachymeningitis is uncommon. We report the first case of pachymeningitis extending to the cerebral parenchyma (pachymeningoencephalitis) and involving the bone and extracranial soft tissue. The clinical features and pathogenesis are discussed.

Giant cell tumor-like cholangiocarcinoma associated with systemic cholelithiasis

A cholangiocarcinoma of the hepatic hilus with an element of giant cell tumor that occurred in a 59‐year‐old man is reported. His medical history included systemic cholelithiasis and repeated operations on the biliary passages. Four years after the last operation, which was a hepatic segmentectomy, he was readmitted because of persistent fever. A computed tomography scan showed a low‐density area and stones in the hepatic hilus. He died of hepatic failure approximately 1 month later. At autopsy, a fist‐sized tumor and gallstones were found at the hepatic hilus. Histologically, the tumor mainly showed sarcomatoid features and some tubular adenocarcinoma. An element of giant cell tumor consisting of many osteo‐clast‐type giant cells also was noted. The results of immunohistochemical studies showed a positive reaction to cytokeratin and vimentin in some of the spindle‐shaped sarcomatoid cells. Sarcomatoid bile duct carcinomas are rare, as are those with osteoclast‐type giant cells. The authors also discuss the histogenesis of these giant cells. Cancer 1992: 69:2444‐2448.

T-cell type primary spinal intramedullary lymphoma associated with human T-cell lymphotropic virus type I after a renal transplant: case report.

We present the first report of primary spinal intramedullary lymphoma of the T-cell type associated with human T-cell lymphotropic virus Type I infection in a 52-year-old woman who had undergone a renal transplant. The pathogenesis of spinal cord T-cell lymphoma is discussed.

Secretory meningioma with lipomatous component: case report

A case of meningioma coexisting with both lipomatous and secretory components, the latter characterized by hyaline inclusion bodies, is reported. The neuroradiological features of lipomeningioma are reevaluated, and the possible pathogenetic mechanisms of this unique combination in the present case are discussed.