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Dive into the research topics where Hasan Turut is active.

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Featured researches published by Hasan Turut.


BMJ Open | 2016

Investigation of surfactant protein-D and interleukin-6 levels in patients with blunt chest trauma with multiple rib fractures and pulmonary contusions: a cross-sectional study in Black Sea Region of Turkey.

Aysel Kurt; Hasan Turut; Ahmet Acipayam; Aynur Kirbas; Suleyman Yuce; Medine Cumhur Cure; Erkan Cure

Objective Multiple rib fractures (RFs) and pulmonary contusions (PCs), with resulting systemic lung inflammation, are the most common injuries caused by blunt chest trauma (BCT) in motor vehicle accidents. This study examined levels of the inflammation marker interleukin (IL)-6 and those of the acute-phase reactant surfactant protein (SP)-D in patients with BCT. Design Prospective, cross-sectional, observational study. Setting Single-centre, tertiary care hospital in the Black Sea Region of Turkey. Participants The study included 60 patients with BCT who were hospitalised in our thoracic surgery department. Parameters measures The SP-D and IL-6 serum levels of patients with RFs (two or more RFs) (n=30) and patients with PCs (n=30) were measured after 6 hours, 24 hours and 7 days, and compared with those of age-matched and gender-matched healthy participants. Results The 6-hour serum SP-D levels of the RFs (p=0.017) and PCs (p<0.001) groups were significantly higher than those of the healthy controls. The 24-hour and 7-day SP-D levels of both groups were also higher than the control group. The serum IL-6 levels of both groups were significantly higher than those of the control group. We have found Injury Severity Score to be independently related to 6-hour IL-6 (β=1.414, p<0.001) and 24-hour IL-6 levels (β=1.067, p<0.001). The development of complications was independently related to 6-hour SP-D level (β=0.211, p=0.047). Conclusions RFs and PCs after BCT lead to local and systemic inflammation due to lung injury. The levels of the systemic inflammation marker IL-6 and those of the acute-phase reactant SP-D were elevated in the present study. The SP-D level may be used as a marker in the follow-up of BCT-related complications.


Archivos De Bronconeumologia | 2015

Efectos protectores de infliximab sobre el daño pulmonar inducido por metotrexato

Aysel Kurt; Levent Tumkaya; Hasan Turut; Medine Cumhur Cure; Erkan Cure; Yildiray Kalkan; Ibrahim Sehitoglu; Ahmet Acipayam

INTRODUCTION Methotrexate (MTX) is used to treat cancers, several forms of arthritis and other rheumatic conditions, although MTX may cause pulmonary toxicity related to the production of free oxygen radicals, various cytokines. Infliximab (IB) with its potent effect on tumor necrosis factor-alpha (TNF-α) inhibition also inhibits the release of endothelin-1 (ET-1). We aimed to investigate whether IB reduces pulmonary damage induced by an overdose of MTX. METHOD The rats were divided into 3 groups of 8 animals. The control group was given only saline. One dose of 20mg/kg MTX intraperitoneal was administered in the MTX group. IB 7 mg/kg was given to the MTX+IB (MI) group. Three days after IB was administered, 20mg/kg MTX was given. Five days after MTX was administered, all rats were sacrificed. RESULTS The TNF-α, ET-1, malondialdehyde (MDA), myeloperoxidase (MPO) and caspase-3 levels in MTX group were significantly higher than in control groups of TNF-α (P=.001), ET-1 (P=.001), MDA (P=.001), MPO (P=.001) and caspase-3 levels (P=.001) and MI groups of TNF-α (P=.009), ET-1 (P=.001), MDA (P=.047), MPO (P=.007) and caspase-3 levels (P=.003). The MI group had less histopathological damage in lung tissue than the MTX group. CONCLUSION Overdose of MTX leads to cytokine release and the formation of reactive oxygen species in addition to increased ET-1 secretion release that causes lung damage. IB, as a potent proinflammatory agent, TNF-α blocker, can decrease ET-1 release and oxidative stress, it may show significant protective effects in lung tissue against damage caused by MTX overdose.


Journal of clinical imaging science | 2013

An Unusual Radiological Presentation of a Pulmonary Hydatid Cyst in a Child

Servet Kayhan; Unal Sahin; Hasan Turut; Cüneyt Yurdakul

Giant pulmonary hydatid cyst is usually encountered in adolescents and children who are older than 10 years. A relatively higher elasticity of the lung tissue allows rapid growth of cysts. We present a case of a 15-year-old male who was admitted with complaint of frequent and persistent dry cough for over a month. Computed tomographic scan revealed a giant cyst with thick enhancing rim and an “air bubble” sign. Diagnosis of giant hydatid cyst was confirmed by surgery and histopathological examination.


Journal of Anesthesia | 2012

The effect of rocuronium, sugammadex, and their combination on cardiac muscle and diaphragmatic skeletal muscle cells

Yildiray Kalkan; Habib Bostan; Levent Tumkaya; Yakup Tomak; Mehmet Bostan; Adnan Yilmaz; Hasan Turut; Ahmet Temiz; Alper Yalçin; Alparslan Turan


Archivos De Bronconeumologia | 2015

Protective Effects of Infliximab on Lung Injury Induced by Methotrexate.

Aysel Kurt; Levent Tumkaya; Hasan Turut; Medine Cumhur Cure; Erkan Cure; Yildiray Kalkan; Ibrahim Sehitoglu; Ahmet Acipayam


Iranian Journal of Basic Medical Sciences | 2015

Is adalimumab protective in ischemia-reperfusion injury in lung?

Aysel Kurt; Levent Tumkaya; Yildiray Kalkan; Hasan Turut; Medine Cumhur Cure; Erkan Cure; Ibrahim Sehitoglu; Hacer Bilgin; Mustafa Usta


Respiratory Case Reports | 2014

A Rare Clinical Entity of Lung Cancer: Metastatic Peripheral Arterial Embolism

Halit Cinarka; Servet Kayhan; Aziz Gumus; Aysel Kurt; Hasan Turut; Gökhan İlhan; Recep Bedir; Unal Sahin


Archive | 2016

Efectos protectores de iniximab sobre el da ˜ no pulmonar inducido por metotrexato

Aysel Kurt; Levent Tumkaya; Hasan Turut; Medine Cumhur Cure; Erkan Cure; Yildiray Kalkan; Ibrahim Sehitoglu; Ahmet Acipayam


Iranian Journal of Basic Medical Sciences | 2016

The protective effect of infliximab against carbon tetrachloride-induced acute lung injury.

Aysel Kurt; Levent Tumkaya; Suleyman Yuce; Hasan Turut; Medine Cumhur Cure; Ibrahim Sehitoglu; Yildiray Kalkan; Gokhan Pusuroglu; Erkan Cure


Archive | 2014

Akciğer Kanserinin Nadir Bir Klinik Tablosu: Metastatik Periferik Arter Embolisi

Halit Cinarka; Servet Kayhan; Aziz Gumus; Aysel Kurt; Hasan Turut; Gökhan İlhan; Recep Bedir; Ünal Şahin

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Aysel Kurt

Recep Tayyip Erdoğan University

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Erkan Cure

Süleyman Demirel University

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Medine Cumhur Cure

Süleyman Demirel University

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Aziz Gumus

Recep Tayyip Erdoğan University

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Halit Cinarka

Recep Tayyip Erdoğan University

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Recep Bedir

Recep Tayyip Erdoğan University

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Servet Kayhan

Recep Tayyip Erdoğan University

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