Hassan M. Mokhtar

Synthesis and Antidiabetic Activity of Some Sulfonylurea Derivatives of 3,4,5-Trisubstituted Pyrazoles

Three series of 3,4,5-trisubstituted pyrazolesulfonylurea derivatives were prepared and evaluated as hypoglycemic agents. Preliminary biological testing revealed that the new compounds possess moderate hypoglycemic activity.

2-Aroylbenzoic acids—VIII: The synthesis and some reactions of 2-aroylbenzoic acids from m-chlorophenol☆

Abstract The syntheses of the novel 2-(4′-chloro-2′-hydroxybenzoyl) benzoic acid 1 and 2-(2′-chloro-4′-hydroxybenzoyl)benzoic acid 2 are described and some of their reactions are given.

Synthesis and spectra of 1-arylpyrazolemonocarboxylic acids

Condensation of 2,4-dioxohexenoates (I) with arylhydrazines (II) led to 1-aryl-3-ethoxycarbonyl-5-styrylpyrazoles (IIIa) which on oxidation and decarboxylation gave 1-phenylpyrazole-3-carboxylic acids (Vb).