Hayat M. Mukhtar

New Compounds from Zizyphus vulgaris

A lanostane-type triterpene, zizyphulanostane-21-oic acid, and a terpenic δ-lactone, zizyphulanostan-18-oic acid, have been isolated from the roots of Zizyphus vulgaris Lam. (syn. Z. sativa Gaertn., Z. mauritina. Lam.) and characterized as lanosta-25 (26)-en-9α-ol-21-oic acid and lanosta-25 (26)-en-22β-ol-18-oic acid 3(19)-olide, respectively, on the basis of spectroscopic techniques and chemical means.

Antihyperglycemic Activity of Cyamopsis tetragonoloba Beans on Blood Glucose Levels in Alloxan-Induced Diabetic Rats

Abstract The effect of administering an ethanol extract of Cyamopsis tetragonoloba. Linn. (Leguminosae) beans on blood glucose levels in normal and alloxan-induced diabetic rats was evaluated in this study. The ethanol extract of beans at 250 mg/kg body weight significantly reduced the blood glucose levels in alloxan-induced diabetic rats within 3 h of administration. Continued administration of the extract at the same dose daily for 10 days produced a statistically significant reduction in the blood glucose levels, whereas marginal activity was seen in normal and glucose-loaded rats.

New Ursane-Type Triterpenes from Zizyphus vulgaris. Roots

Abstract Two new ursane-type triterpenes, zizyphursolic acid (1), and isozizyphursolic acid (2), have been isolated from the roots of Zizyphus vulgaris. Lam. (syn: Z. sativa. Gaertn.; Z. mauritiana. Lamk.) and characterized as 18β.H-urs-20 (30)-en-3β.-ol-28-oic acid and 18β.H-urs-20 (30)-en-2α.-ol-28-oic acid, respectively. Their structures were elucidated by spectroscopic (UV, IR, NMR, and MS) methods and chemical reactions.

A New d-Lactone Containing Triterpene from the Flowers of Calendula officinalis

A new δ-lactone containing triterpene, 4β-methylcholest-20-en-12a-ol-3β-olide, was isolated from Calendula officinalis Linn. flowers in addition to three known compounds, lanast-20(22)-en-3β-ol, stigmast-5,22-dien-3β-ol, and stigmast-5,24(28)-dien-3β-ol. Their structures were elucidated by spectroscopic (UV, IR, NMR, and MS) methods and chemical reactions.