Heinz-Jürgen Wroblowsky

Binding of Triazines and Triazinones in the QB-Binding Niche of Photosystem II

Abstract A series of 20 triazines (derivatives of 2-alkylamino-4-benzylam ino-6-chloro-1,3,5-triazines) and 37 triazinones (derivatives of 3-alkyl-4-amino-6-phenyl-1,2,4-triazin-5-ones) is tested for inhibitory potency in photosynthetic electron flow through photosystem II of wild type Chlamydomonas reinhardtii and of five mutants with aminoacid substitutions in the D 1 protein at valine 219, alanine 251, phenylalanine 255, serine 264, and leucine 275. The data are used for computer modelling of the possible location of the compounds within a three dimensional model of the QB-binding niche of the D 1 protein.