Helen M. Free

A simplified urine and serum screening test for salicylate intoxication

The extremely high incidence of salicylate intoxication makes it desirable to have a screening test available. Such a procedure should be simple and rapid enough to be used routinely on all admission and emergency cases since salicylate intoxication may not be suspected. This report describes studies with a stick test used on urine and serum. Test results agree well with quantitative measurements. Specimens tested included urine and serum from dogs and human beings after experimental administration of aspirin as well as samples from cases of salicylate intoxication or high therapeutic salicylate levels. The test strip develops an immediate brownish purple color with as little as 20 mg. per cent free salicylate. Data are presented to show that reliable results are obtained with the test even by inexperienced individuals.

Urine Glucose Tests for Diabetic Patients with Impaired Vision

A colorimetric test procedure called Mega-Diastix is described for detection and measurement of glucose in urine. The test is designed for use by diabetic patients with impaired vision. Data establishing the performance capabilities of this rapid, convenient test are presented. As an internal standard, the recommended procedure utilizes effervescent control tablets for preparation of simulated urine. Also described is a touch fermentation test for detection of urinary glucose by totally blind patients. Data are given that demonstrate the accuracy and ease of performance of this test, which entails a rapid yeast fermentation. An internal standard is also incorporated into the procedure for this test.