Helen Y. Chen | Researchain

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Featured researches published by Helen Y. Chen.

Journal of Medicinal Chemistry | 2000

Structure−Activity Relationship Studies on 1-[2-(4-Phenylphenoxy)ethyl]pyrrolidine (SC-22716), a Potent Inhibitor of Leukotriene A4 (LTA4) Hydrolase

Thomas D. Penning; Nizal S. Chandrakumar; Barbara B. Chen; Helen Y. Chen; Bipin N. Desai; Stevan W. Djuric; Stephen H Docter; Alan F. Gasiecki; Richard A. Haack; Julie M. Miyashiro; Mark A. Russell; Stella S. Yu; David G. Corley; Richard C. Durley; Brian F. Kilpatrick; Barry L. Parnas; Leslie J. Askonas; James K. Gierse; Elizabeth I. Harding; Maureen K. Highkin; James F. Kachur; Suzanne H. Kim; Gwen G. Krivi; Doreen Villani-Price; E. Yvonne Pyla; and Walter G. Smith; Nayereh S. Ghoreishi-Haack

Journal of Medicinal Chemistry | 2002

Synthesis of potent leukotriene a4 hydrolase inhibitors. Identification of 3-[methyl[3-[4-(phenylmethyl)phenoxy]propyl]amino]propanoic acid

Thomas D. Penning; Mark A. Russell; Barbara B. Chen; Helen Y. Chen; Chi-Dean Liang; Matthew W. Mahoney; James W. Malecha; Julie M. Miyashiro; Stella S. Yu; Leslie J. Askonas; James K. Gierse; Elizabeth I. Harding; Maureen K. Highkin; James F. Kachur; Suzanne H. Kim; Doreen Villani-Price; E. Yvonne Pyla; Nayereh S. Ghoreishi-Haack; Walter G. Smith

Bioorganic & Medicinal Chemistry Letters | 2004

Synthesis of cinnamic acids and related isosteres as potent and selective αvβ3 receptor antagonists

Thomas D. Penning; Mark A. Russell; Barbara B. Chen; Helen Y. Chen; Bipin N. Desai; Stephen H. Docter; David J. Edwards; Glen J. Gesicki; Chi-Dean Liang; James W. Malecha; Stella Siu-Tzyy Yu; V. Wayne Engleman; Sandra K. Freeman; Melanie L. Hanneke; Kristen E. Shannon; Marisa M. Westlin; G. Allen Nickols

Archive | 1998

Inhibiteurs de lta4 hydrolase

Barbara B. Chen; Helen Y. Chen; Mark A. Russell; Julie M. Miyashiro; James W. Malecha; Thomas D. Penning

Archive | 1997

Phenylene derivatives substituted in meta and their use as antagonists or inhibitors of integrin alphav, beta3.

Nizal S. Chandrakumar; Barbara B. Chen; Helen Y. Chen; Michael Clare; Alan F. Gasiecki; Richard A. Haack

Archive | 1997

META-SUBSTITUTED PHENYLENDERIVATE AND THEIR USE AS alphavbeta3 INTERGRIN ANTAGONISTS OR INHIBITORS

Nizal S. Chandrakumar; Beiyun Chen; Helen Y. Chen; Michael Clare; F Gasiecki; A Haack; W Malecha; G Ruminski; A Russell

Archive | 1997

Ciclopropilalcanoicos acid derivatives.

Barbara B. Chen; Helen Y. Chen; Michael Clare; Shashidhar N. Rao; Mark A. Russell

Archive | 1997

META-SUBSTITUIERTE PHENYLENDERIVATE UND IHRE VERWENDUNG ALS ALPHAvBETA3 INTERGRIN-ANTAGONISTEN ODER INHIBITOREN META-SUBSTITUTED PHENYLENDERIVATE AND THEIR USE AS alphavbeta3 INTERGRIN ANTAGONISTS OR INHIBITORS

Nizal S. Chandrakumar; Beiyun Chen; Helen Y. Chen; Michael Clare; F Gasiecki; A Haack; W Malecha; G Ruminski; A Russell

Archive | 1997

Derives de l'acide alcanoique de cyclopropyle

Barbara B. Chen; Helen Y. Chen; Michael Clare; Shashidhar N. Rao; Mark A. Russell

Archive | 1997

Para-substituierte phenylpropansäure derivate als integrin-antagonisten

Barbara B. Chen; Helen Y. Chen; Glen J. Gesicki; Richard A. Haack; James W. Malecha; Thomas D. Penning; Joseph G. Rico; Thomas Edward Rogers; Peter G. Ruminski; Mark A. Russell; Stella S. Yu

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