Hélène Ginsburg

Reactions SRN1: partie no 18. action de sulfanions derives de HS(CH2)nSH vis-a-vis des halo-1 et -2 naphtalenes

Abstract A double S RN 1 reaction was shown to occur between HS(CH 2 ) n SH and 1 or 2 halonaphtalene to give the corresponding double sulfides Napht 1(2) S(CH 2 ) n SNapht 1(2) (n = 2, 3, 4)

Studies on SRN1 reactions. Part 6: synthesis of 3-methyl derivatives of the alkaloids thalactamine, doryanine, and 6,7-dimethoxy-N-methyl-1(2H)-isoquinolone

A new, short synthesis of the 3-methyl derivatives (3a–c) of the alkaloids thalactamine, doryanine, and 6,7-dimethoxy-N-methyl-1(2H)-isoquinolone, based upon our previous SRN1 synthesis 1 of isocarbostryril [1(2H)-isoquinolone] systems, is reported.

Use of tetrabutylammonium cyanide for photocyanation of aromatic compounds: phase transfer photochemistry

Nucleophilic aromatic photosubstitution can be carried out using tetrabutylammonium cyanide in anhydrous acetonitrile or methylene chloride and also under phase-transfer conditions (CH2Cl2–KCN in H2O).

New synthesis of benzo[b]furans by SRN1 reaction of ortho-iodoanisole

Starting from ortho-iodoanisole, 2-substituted benzo[b]furans are obtained in high yield via aromatic nucleophilic radical substitution (SRN1).