Henry A. Bartels

Survey of the Yeast Population in Saliva and an Evaluation of Some Procedures for Identification of Candida albicans

A number of investigators during the last 25 years have reported on the frequency and distribution of yeasts and yeastlike organisms in the oral cavities and throats of apparently normal individuals and those with systemic or mycotic disease.12 For a comprehensive review of the literature prior to 1939, the reader is referred to a paper by Knighton.2 During the past decade, a number of selective enrichment and differential media have been introduced for the isolation and identification of yeasts and yeastlike micro-organisms. It was the purpose of this study to apply a number of the newer procedures to a survey of the yeast populations of the oral cavity.

A study of some factors associated with endodontic “flare-ups”

A study was undertaken by the TS others were broken during transit, as a result of improper packing; and in some instances x-ray films were not submitted. Thus, in the accompanying tables the total numbers of cases in various categories are not identical.

The inhibitory action of stimulated whole saliva on the in vitro growth of clostridium tetani

Abstract Freshly stimulated saliva exhibits an inhibitory action toward the tetanus bacillus. The factor is distinct from lysozyme and is not filterable through the Seitz filter. It appears to be associated with the oral microbiota. Exposure of tetanus spores to the oral microbiota does not destroy them but does inhibit their germination.

Factors Which Influence the Assay of the Antilactobacillus Agent in Saliva

Demonstration of the antilactobacillus agent is dependent on the amount present in saliva specimens. The medium employed in performing the tests, Rogosas medium, gave the best reproducible results. Variation in sensitivity of lactobacillus species and the occurrence of resistant mutants were determined.

The in Vitro Activity of the Antilactobacillus Factor toward Various Species of Lactobacilli

The mechanism by which the salivary antilactobacillus factor (lactocidin) inhibits lactobacilli has been described by Zeldow (J. dent. Res., 38:798-804, 1959; J. dent. Res., 40:446-53, 1961; J. Immunol., 90:12-16, 1963) and confirmed by Dogan, Kerr, and Amdur (Arch. oral Biol., 7:81-90, 1962) and Matsumura, Morioka, Onishi, and Go (Dent. Bull. Osaka Univ., 1:3-11, 1960). During an investigation of this activity according to the technique described by Zeldow (J. dent. Res., 38:798, 1959), it was observed that oral lactobacilli isolates were not always inhibited by saliva specimens. These cultures were subsequently identified as strains of L. case, L. acidophilus, and L. plantarum. Other species of lactobacilli obtained from

Further observations on the in vitro activity of the anti-hemolytic streptococcus factor present in saliva

Abstract The anti-beta hemolytic streptococcus factor was found to be intimately associated with the in vitro metabolism of actively growing oral microorganisms. A relationship was noted between the numbers of oral microbial colonies and the relative concentration of the inhibiting agent. The factor was found to be distinct from biogenic hydrogen peroxide and acid production.