Herman L. Gardner

HEMOPHILUS VAGINALIS VAGINITIS

That a widespread, nontrichomonal, malodorous leukorrhea exists that has been attributed in the past to “nonspecific” bacterial vaginitis is undeniable. Clinical descriptions of “nonspecific” vaginitis appearing in the literature are rare and grossly inadequate, but the clinical pattern is far more uniform than that observed in vaginal trichomoniasis or moniliasis. The etiology of nonspecific vaginitis has been postulated in the past, although seemingly contrary to the usual rules of medical logic, as being of mixed bacterial character, with the various streptococci, staphylococci, micrococci, diphtheroids, and coliform bacilli being most often incriminated. In a preliminary report in 1Y54I and a more detailed report, in 195Y we presented evidence that over 90 per cent of so-called nonspecific vaginal infections belong to a specific disease ent,ity caused by a single bacterial species, namely, Hemophilus caginalis. Our additional years of experience have added only confirmation to our previously published opinions, and these opinions have also been largely confirmed by Lutz et ~ l . , ~ Kay and M a ~ g b a n , ~ Amies and Jones; Brewer et al.,’j and S t e ~ a r t . ~ Deming8 described a closely similar, if not identical, entity hut identified his causative bacterium as H . injuenzae. Heltai and TaleghanyQ report.ed isolating H . vaginalis 30 times from 127 clinic patients but, according to t.heir material and methods, were unwilling to assign H . zraginalis a more significant role than numerous other organisms. Consequently, they questioned the existence of a specific entity and preferred to adhere to the concept of a mixed bacterial etiology. Hunter and Longlo apparently failed to identify the organism in a group of 87 patients.

Desquamative inflammatory vaginitis: a newly defined entity.

Abstract Eight cases of a newly described type of vaginitis are reported. In many respects, this vaginitis resembles atrophic vaginitis, although it appears in women with normal estrogen levels. Its etiology is as yet undetermined. With or without treatment, the disease runs a protracted course. Thus far, intravaginal applications of preparations containing a corticosteroid have proved to be the most effective treatment.

Anterior ocular ovarian grafts in the rabbit: A potential tool in endocrine investigation for clinician and scientist☆☆☆

Abstract 1. 1. The transplantability of autologous and homologous ovarian tissue has been shown to be relatively high and the technique of transplantation simple. 2. 2. The employment of ovarian transplants in a biologic test for gonadotropin (modified Friedman) has been shown to be feasible. 3. 3. The practicability of visualizing continuously the inhibiting and stimulating effects of hormones on the transplanted rabbit ovary has been further demonstrated. 4. 4. That ovarian tissue can be made completely refractory to gonadotropic stimulation by estrogens has been conclusively shown.

Transplantability of Rabbit Ovaries in the Anterior Chamber of the Rabbit Eye.

Summary In 112 autologous and homologous anterior chamber grafts of ovarian tissue in castrate and non-castrate males, and spayed and non-spayed females, the percentage of homologous takes was highest in non-spayed females, next highest in castrate males and spayed females. The lowest percentage of such takes was in normal males. The incidence in the different categories is not considered to be statistically significant with the possible exception of the non-spayed group of females. The ages of the donor grafts were not significant in relation to growth of fragments at the ages investigated. There was no apparent influence of the tissue transplants upon the weight gain of the recipient rabbits.