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Dive into the research topics where Hey-Jung Park is active.

Publication


Featured researches published by Hey-Jung Park.


Scientific Reports | 2017

Functional Evaluation of a Bioartificial Liver Support System Using Immobilized Hepatocyte Spheroids in a Porcine Model of Acute Liver Failure

Ji-Hyun Lee; Doo-Hoon Lee; Sang Hoon Lee; Choon Hyuck David Kwon; Jae-Nam Ryu; Jeong-Kwon Noh; In Keun Jang; Hey-Jung Park; Hee-Hoon Yoon; Jung-Keug Park; Young-Jin Kim; Sung-Koo Kim; Suk-Koo Lee

Bioartificial livers (BAL) may offer acute liver failure (ALF) patients an opportunity for cure without liver transplantation. We evaluated the efficacy of a spheroid-based BAL system, containing aggregates of porcine hepatocytes, in a porcine model of ALF. ALF pigs were divided into three groups. The control group consisted of treatment naïve pigs (n = 5), blank group consisted of pigs that were attached to the BAL system not containing hepatocytes for 12 hours (n = 5) and BAL group consisted of pigs that were attached to the BAL containing hepatocytes for 12 hours (n = 5). Increase in serum ammonia levels were significantly greater in the blank group (P < 0.01) and control group (P < 0.01), compared to the BAL group during the treatment period. Increase in ICP was significantly greater in the control group compared to the BAL group (P = 0.01). Survival was significantly prolonged in the BAL group compared to the blank group (P = 0.03). A BAL system with a bioreactor containing hepatocyte spheroids showed effective clearance of serum ammonia, preservation of renal function and delayed ICP increase in a porcine model of ALF.


Archive | 2008

APPARATUS AND METHOD OF MANUFACTURING ASEPTIC CAPSULES

Jung Keug Park; Sung Koo Kim; Suk Koo Lee; Young-Jin Kim; Doo-Hoon Lee; Ji-Hyun Lee; Hee-Hoon Yoon; Jae-Nam Ryu; Choon-Hyuck Kwon; Jeong-Kwon Noh; Hey-Jung Park


Archive | 2008

Bioartificial liver system using bioreactor packed with gel beads

Jung Keug Park; Sung Koo Kim; Suk Koo Lee; Young-Jin Kim; Doo-Hoon Lee; Ji-Hyun Lee; Hee-Hoon Yoon; Jae-Nam Ryu; Choon-Hyuck Kwon; Jeong-Kwon Noh; Hey-Jung Park


Transplantation | 2018

Hepatocyte Transplant and Bridge to Subsequent Liver Transplant in an Infant with Carbamoyl Phosphate Synthetase Deficiency

Sanghoon Lee; Sungyoon Cho; Ji Hyun Lee; Sojeong Yoon; Seung Wook Han; Hey-Jung Park; Young-A Kim; Mi Na Park; Suk-Koo Lee


Transplantation | 2018

Phase 1/2a Trial of a Bioartificial Liver Support System (LifeLiver) for Acute Liver Failure Patients

Sanghoon Lee; Ji Hyun Lee; Doo-Hoon Lee; Hey-Jung Park; Young-A Kim; Mi Na Park; Jeong-Kwon Noh; Jong Gab Jung; Jongeun Lee; Mal Sook Yang; Eun Mi Jang; Hee-Hoon Yoon; Sojeong Yoon; Seung Wook Han; Suk-Koo Lee


Clinical Therapeutics | 2015

Effect of Cilostazol on The Pharmacodynamics of Cyp3a and Non-Cyp3a-Dependent Statins

J.A. Jung; Sun-Mee Lee; Hey-Jung Park; Jeong-Ae Kim; Wooseong Huh; J.W. Ko


Archive | 2008

Bioartificial liver system using a column packed with gel beads bioreactor

Sung Koo Kim; Young-Jin Kim; Choon-Hyuck Kwon; Doo-Hoon Lee; Ji-Hyun Jinhae Lee; Suk Koo Lee; Jeong-Kwon Noh; Hey-Jung Park; Jung Keug Park; Jae-Nam Ryu; Hee-Hoon Yoon


Archive | 2008

Bioartifizielles Lebersystem, das einen mit Gelperlen gepackten Bioreaktor verwendet

Sung Koo Kim; Young-Jin Kim; Choon-Hyuck Kwon; Doo-Hoon Lee; Ji-Hyun Jinhae Lee; Suk Koo Lee; Jeong-Kwon Noh; Hey-Jung Park; Jung Keug Park; Jae-Nam Ryu; Hee-Hoon Yoon


Archive | 2008

Bioartifizielles Lebersystem, das einen mit Gelperlen gepackten Bioreaktor verwendet Bioartificial liver system using a bioreactor packed with gel beads

Sung Koo Kim; Young-Jin Kim; Choon-Hyuck Kwon; Doo-Hoon Lee; Ji-Hyun Jinhae Lee; Suk Koo Lee; Jeong-Kwon Noh; Hey-Jung Park; Jung Keug Park; Jae-Nam Ryu; Hee-Hoon Yoon


Archive | 2008

Vorrichtung und Verfahren zum Herstellen aseptischer Kapseln Apparatus and method for manufacturing aseptic capsules

Jung Keug Park; Sung Koo Kim; Suk Koo Lee; Young-Jin Kim; Doo-Hoon Lee; Ji-Hyun Lee; Hee-Hoon Yoon; Jae-Nam Ryu; Choon-Hyuck Kwon; Jeong-Kwon Noh; Hey-Jung Park

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Ji-Hyun Lee

Samsung Medical Center

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Suk Koo Lee

Samsung Medical Center

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Suk-Koo Lee

Samsung Medical Center

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Sung-Koo Kim

Pukyong National University

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