Hey-Jung Park
Samsung Medical Center
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Publication
Featured researches published by Hey-Jung Park.
Scientific Reports | 2017
Ji-Hyun Lee; Doo-Hoon Lee; Sang Hoon Lee; Choon Hyuck David Kwon; Jae-Nam Ryu; Jeong-Kwon Noh; In Keun Jang; Hey-Jung Park; Hee-Hoon Yoon; Jung-Keug Park; Young-Jin Kim; Sung-Koo Kim; Suk-Koo Lee
Bioartificial livers (BAL) may offer acute liver failure (ALF) patients an opportunity for cure without liver transplantation. We evaluated the efficacy of a spheroid-based BAL system, containing aggregates of porcine hepatocytes, in a porcine model of ALF. ALF pigs were divided into three groups. The control group consisted of treatment naïve pigs (n = 5), blank group consisted of pigs that were attached to the BAL system not containing hepatocytes for 12 hours (n = 5) and BAL group consisted of pigs that were attached to the BAL containing hepatocytes for 12 hours (n = 5). Increase in serum ammonia levels were significantly greater in the blank group (P < 0.01) and control group (P < 0.01), compared to the BAL group during the treatment period. Increase in ICP was significantly greater in the control group compared to the BAL group (P = 0.01). Survival was significantly prolonged in the BAL group compared to the blank group (P = 0.03). A BAL system with a bioreactor containing hepatocyte spheroids showed effective clearance of serum ammonia, preservation of renal function and delayed ICP increase in a porcine model of ALF.
Archive | 2008
Jung Keug Park; Sung Koo Kim; Suk Koo Lee; Young-Jin Kim; Doo-Hoon Lee; Ji-Hyun Lee; Hee-Hoon Yoon; Jae-Nam Ryu; Choon-Hyuck Kwon; Jeong-Kwon Noh; Hey-Jung Park
Archive | 2008
Jung Keug Park; Sung Koo Kim; Suk Koo Lee; Young-Jin Kim; Doo-Hoon Lee; Ji-Hyun Lee; Hee-Hoon Yoon; Jae-Nam Ryu; Choon-Hyuck Kwon; Jeong-Kwon Noh; Hey-Jung Park
Transplantation | 2018
Sanghoon Lee; Sungyoon Cho; Ji Hyun Lee; Sojeong Yoon; Seung Wook Han; Hey-Jung Park; Young-A Kim; Mi Na Park; Suk-Koo Lee
Transplantation | 2018
Sanghoon Lee; Ji Hyun Lee; Doo-Hoon Lee; Hey-Jung Park; Young-A Kim; Mi Na Park; Jeong-Kwon Noh; Jong Gab Jung; Jongeun Lee; Mal Sook Yang; Eun Mi Jang; Hee-Hoon Yoon; Sojeong Yoon; Seung Wook Han; Suk-Koo Lee
Clinical Therapeutics | 2015
J.A. Jung; Sun-Mee Lee; Hey-Jung Park; Jeong-Ae Kim; Wooseong Huh; J.W. Ko
Archive | 2008
Sung Koo Kim; Young-Jin Kim; Choon-Hyuck Kwon; Doo-Hoon Lee; Ji-Hyun Jinhae Lee; Suk Koo Lee; Jeong-Kwon Noh; Hey-Jung Park; Jung Keug Park; Jae-Nam Ryu; Hee-Hoon Yoon
Archive | 2008
Sung Koo Kim; Young-Jin Kim; Choon-Hyuck Kwon; Doo-Hoon Lee; Ji-Hyun Jinhae Lee; Suk Koo Lee; Jeong-Kwon Noh; Hey-Jung Park; Jung Keug Park; Jae-Nam Ryu; Hee-Hoon Yoon
Archive | 2008
Sung Koo Kim; Young-Jin Kim; Choon-Hyuck Kwon; Doo-Hoon Lee; Ji-Hyun Jinhae Lee; Suk Koo Lee; Jeong-Kwon Noh; Hey-Jung Park; Jung Keug Park; Jae-Nam Ryu; Hee-Hoon Yoon
Archive | 2008
Jung Keug Park; Sung Koo Kim; Suk Koo Lee; Young-Jin Kim; Doo-Hoon Lee; Ji-Hyun Lee; Hee-Hoon Yoon; Jae-Nam Ryu; Choon-Hyuck Kwon; Jeong-Kwon Noh; Hey-Jung Park