Hideki Niwa
Osaka University
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Featured researches published by Hideki Niwa.
Surgery Today | 1989
Hideki Niwa; Yoshitaka Ogawa; Yoshihiro Kido; Yoshio Abe; Mitsugu Kobayashi; Takesada Mori; Takehiko Tanaka
In order to examine the rate of lipid oxidation in sepsis, lipid infusion studies were carried out using two experimental models of septic rats, namely; an endotoxin group, and a cecum ligation and puncture group. Following the administration of glucose at a caloric amount equivalent to the measured resting energy expenditure (REE), the respiratory quotient (RG) values dropped promptly in the control group, but decreased only slightly in the septic groups. Following the administration of a lower dose of glucose (0.5 kcal/100 g B.W./hr), however, a lipid infusion promptly decreased the value of RQ in the septic groups. These results suggest that lipid oxidation was depressed in the septic groups and that the degree of depression was greatly influenced by the relationship between REE and the amount of administered glucose.
Surgery Today | 1988
Motohiko Naruko; Yoshitaka Ogawa; Yoshihiro Kido; Hideki Niwa; Yoshio Abe; Mitsugu Kobayashi; Takesada Mori; Takehiko Tanaka
Energy expenditure was studied in male Donryu rats, following two types of surgical stress, namely, laparotomy and burns. The rats with burns were subsequently fasted for 6 hours, by which time the resting metabolic expenditure (RME) became significantly decreased (84.3±9.5 per cent), as when compared to the pre-burn value (100 per cent), then increased 24 hours after the burn (132.9±10.1 per cent). The RME in burned rats receiving an intravenous infusion of electrolyte fluid, slightly increased 6 hours after the burn (109.0±15.8 per cent) and was almost identical to the RME in rats fedad libitum for 24 hours after the burn. Rats with burns, that were given intravenous infusions of electrolytes and nutrients (TPN) already had a high RME value (134.6±7.0 per cent) 6 hours after the burn. In laparotomized rats fedad libitum, no obvious changes in energy expenditure were observed 6 hours or 24 hours after the laparotomy, however, rats receiving TPN showed a moderately increased RME 6 hours after the laparotomy (113.9±3.4 per cent, p<0.05) which returned to the pre-stress level 24 hours post-operatively. These results confirmed that a phase of decreased RME (ebb phase), followed by a phase of increased RME were clearly observed after severe surgical stress, which indicated that appropriate treatments could shorten or extinguish the ebb phase.
Surgery Today | 1988
Motohiko Naruko; Yoshitaka Ogawa; Yoshihiro Kido; Hideki Niwa; Yoshio Abe; Mitsugu Kobayashi; Takesada Mori; Takehiko Tanaka
The correlation between energy expenditure and hormonal changes following surgical stress was studied using rats. Blood concentrations of catecholamine, insulin, corticosterone, glucagon, T3, and T4 were compared between the rats (IIa and IIb) in the ebb phase and those (III and IV) in the flow phase, 6 hours after being inflicted with a burn. Noradrenaline was higher, though not significantly, and glucagon was significantly higher in the latter groups than in the former groups. When glucagon was administered to the rats in the ebb phase, RME increased significantly. From these results, it is suggested that glucagon plays an important role in the transition from ebb phase to flow phase.
Nihon Rinsho Geka Gakkai Zasshi (journal of Japan Surgical Association) | 1995
Atsuhiro Ogawa; Hideki Niwa; Tsuyoshi Yamada; Yoshihiko Hayashida; Yoshitaka Ogawa; Yoji Kobayashi
Nihon Gekakei Rengo Gakkaishi (journal of Japanese College of Surgeons) | 2017
Masaki Shimizu; Minoru Ogawa; Tetsuya Shirota; Atsuhiro Ogawa; Makoto Watase; Hideki Niwa
Nihon Rinsho Geka Gakkai Zasshi (journal of Japan Surgical Association) | 2016
Ayako Kanamoto; Kaname Ishii; Toshiya Takeda; Takashi Tani; Masao Yagi; Hideki Niwa
Nihon Rinsho Geka Gakkai Zasshi (journal of Japan Surgical Association) | 2014
Hideki Niwa; Minoru Ogawa; Takuya Yamaguchi; Norifumi Hirooka; Takatoshi Kadowaki; Makoto Watase
Nihon Gekakei Rengo Gakkaishi (journal of Japanese College of Surgeons) | 2014
Norifumi Hirooka; Takugi Mori; Takuya Yamaguchi; Tetsuya Shirota; Minoru Ogawa; Atsuhiro Ogawa; Takatoshi Kadowaki; Makoto Watase; Goro Tachiyama; Hideki Niwa
Nihon Rinsho Geka Gakkai Zasshi (journal of Japan Surgical Association) | 2012
Tetsuya Shirota; Makoto Watase; Mikio Nanbara; Ryou Tanaka; Takuya Yamaguchi; Norifumi Hirooka; Takuji Mori; Minoru Ogawa; Atsuhiro Ogawa; Takatoshi Kadowaki; Hideki Niwa
Nihon Rinsho Geka Gakkai Zasshi (journal of Japan Surgical Association) | 2012
Minoru Ogawa; Makoto Watase; Takuya Yamaguchi; Mikio Nanbara; Ryo Tanaka; Hideki Niwa