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Featured researches published by Hidemi Shiomoto.


Yakugaku Zasshi-journal of The Pharmaceutical Society of Japan | 1992

生薬・ウワウルシの薬理学的研究(第4報) : メラニン色素合成系に及ぼすウワウルシ50%メタノール抽出エキスの影響

Hideaki Matsuda; Shinsuke Nakamura; Hidemi Shiomoto; Takayuki Tanaka; Michinori Kubo

Effects of 50% methanolic extract (U-ext) from the leaf of Arctostaphylos uva-ursi (L.) Spreng. (bearberry leaf) on melanin synthesis were investigated in vitro. The U-ext and arbutin isolated from the bearberry leaf had an inhibitory effect on tyrosinase activity. Furthermore, the U-ext inhibited the production of melanin from dopa by tyrosinase and from dopachrome by autoxidation. These results suggest that the bearberry leaf was found to be an effective inhibitor of the production of melanin.


Biological & Pharmaceutical Bulletin | 1994

Studies on Rehmanniae Radix. I. Effect of 50% Ethanolic Extract from Steamed and Dried Rehmanniae Radix on Hemorheology in Arthritic and Thrombosic Rats

Michinori Kubo; Toshiki Asano; Hidemi Shiomoto; Hideaki Matsuda


Planta Medica | 1988

Anti-Thrombic Action of Methanol Extract and Alkaloidal Components from Corydalis Tuber

Hideaki Matsuda; Hidemi Shiomoto; Shunsuke Naruto; Kensuke Namba; Michinori Kubo


Biological & Pharmaceutical Bulletin | 1997

Inhibitory Effects of Dehydrocorydaline Isolated from Corydalis Tuber against Type I-IV Allergic Models

Hideaki Matsuda; Kiyoshi Tokuoka; Jianxin Wu; Hidemi Shiomoto; Michinori Kubo


Yakugaku Zasshi-journal of The Pharmaceutical Society of Japan | 1990

Phagocytic Activity of Leaves of Epimedium Species on Mouse Reticuloendotherial System

Munekazu Iinuma; Toshiyuki Tanaka; Norio Sakakibara; Mizuno Mizuno; Hideaki Matsuda; Hidemi Shiomoto; Michinori Kubo


Archive | 2003

Peroral composition for preventing and treating climacteric symptom

Toshiki Asano; Michio Kurachi; Hidemi Shiomoto; 道雄 倉地; 秀己 塩本; 年紀 浅野


Archive | 2004

Prophylactic or therapeutic agent composition for menopausal syndrome

Hidemi Shiomoto; 秀己 塩本


Chemical & Pharmaceutical Bulletin | 1990

Effects of protopine on blood platelet aggregation. II, Effect on metabolic system of adenosine 3',5'-cyclic monophosphate in platelets

Hidemi Shiomoto; Hideaki Matsuda; Michinori Kubo


Archive | 2003

Ameliorating agent composition for lifestyle-related illness

Toshiki Asano; Michio Kurachi; Hidemi Shiomoto; 道雄 倉地; 秀己 塩本; 年紀 浅野


Chemical & Pharmaceutical Bulletin | 1991

Effects of Protopine on Blood Platelet Aggregation. III. Effect of Protopine on the Metabolic System

Hidemi Shiomoto; Hideaki Matsuda; Michinori Kubo

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Hideaki Matsuda

China Pharmaceutical University

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Toshiki Asano

Taisho Pharmaceutical Co.

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Kazumi Osada

Health Sciences University of Hokkaido

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Michinori Kubo

China Pharmaceutical University

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