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Hidemichi Mizuguchi

University of Tokyo

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Featured researches published by Hidemichi Mizuguchi.

Tetrahedron Letters | 1979

Novel isomerization of dibenzocyclooctadiene lignan lactone —first synthesis of (±)-stegane—

Kiyoshi Tomioka; Hidemichi Mizuguchi; Kenji Koga

Abstract (±)-Isostegane isomerized into (+-)-isopicrostegane, (±)-picrostegane, and (±)-stegane, the parent compound o steganacin-type dibenzocyclooctadiene lignan lactones.

Journal of Medicinal Chemistry | 1991

Absolute structure-cytotoxic activity relationships of steganacin congeners and analogues

Kiyoshi Tomioka; Tsuneo Ishiguro; Hidemichi Mizuguchi; Nobuyasu Komeshima; Kenji Koga; Shigeru Tsukagoshi; Takashi Tsuruo; Tazuko Tashiro; Seiichi Tanida; Toyokazu Kishi

Chemical & Pharmaceutical Bulletin | 1982

Stereoselective Reactions. V. Design of the Asymmetric Synthesis of Lignan Lactones. Synthesis of optically Active Podorhizon and Deoxypodorhizon by 1, 3-Asymmetric Induction

Kiyoshi Tomioka; Hidemichi Mizuguchi; Kenji Koga

Chemical & Pharmaceutical Bulletin | 1985

Stereoselective reactions. VIII: Stereochemical requirement for the benzylic oxidation of lignan lactone. A highly selective synthesis of the antitumor lignan lactone steganacin by the oxidation of stegane

Tsuneo Ishiguro; Hidemichi Mizuguchi; Kiyoshi Tomioka; Kenji Koga

Tetrahedron Letters | 1978

Studies directed towards the asymmetric total synthesis of antileukemic lignan lactones —synthesis of (−)-podorhizon—

Kiyoshi Tomioka; Hidemichi Mizuguchi; Kenji Koga

Chemical & Pharmaceutical Bulletin | 1985

Stereoselective Reactions. VII. Synthesis of Racemic and Optically Pure Stegane, Isostegane, Picrostegane, and Isopicrostegane via Highly Selective Isomerization

Kiyoshi Tomioka; Hidemichi Mizuguchi; Tsuneo Ishiguro; Kenji Koga

ChemInform | 1981

Synthetic Studies Using the Optically Active g-Lactone Derivative as a Chiral Synthon. Asymmetric Total Synthesis of Antileukemic Lignan Steganacin

Kiyoshi Tomioka; Tsuneo Ishiguro; Hidemichi Mizuguchi; Kenji Koga

ChemInform | 1985

STEREOSELECTIVE REACTIONS. VIII. STEREOCHEMICAL REQUIREMENT FOR THE BENZYLIC OXIDATION OF LIGNAN LACTONE. A HIGHLY SELECTIVE SYNTHESIS OF THE ANTITUMOR LIGNAN LACTONE STEGANACIN BY THE OXIDATION OF STEGANE

Tsuneo Ishiguro; Hidemichi Mizuguchi; Kiyoshi Tomioka; Kenji Koga

ChemInform | 1985

STEREOSELECTIVE REACTIONS. VII. SYNTHESIS OF RACEMIC AND OPTICALLY PURE STEGANE, ISOSTEGANE, PICROSTEGANE, AND ISOPICROSTEGANE VIA HIGHLY SELECTIVE ISOMERIZATION

Kiyoshi Tomioka; Hidemichi Mizuguchi; Tsuneo Ishiguro; Kenji Koga

ChemInform | 1983

STEREOSELECTIVE REACTIONS. V. DESIGN OF THE ASYMMETRIC SYNTHESIS OF LIGNAN LACTONES. SYNTHESIS OF OPTICALLY ACTIVE PODORHIZON AND DEOXYPODORHIZON BY 1,3-ASYMMETRIC INDUCTION

Kiyoshi Tomioka; Hidemichi Mizuguchi; Kenji Koga

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Kenji Koga

University of Tokyo

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Kiyoshi Tomioka

Doshisha Women's College of Liberal Arts

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Tsuneo Ishiguro

University of Tokyo

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Nobuyasu Komeshima

University of Tokyo

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Seiichi Tanida

Takeda Pharmaceutical Company

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Takashi Tsuruo

Japanese Foundation for Cancer Research

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Tazuko Tashiro

Japanese Foundation for Cancer Research

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Toyokazu Kishi

Takeda Pharmaceutical Company

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Shigeru Tsukagoshi

Cancer Institute

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