Hidetaka Niitsu
Akita University
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Publication
Featured researches published by Hidetaka Niitsu.
The American Journal of the Medical Sciences | 1994
Akihiko Chubachi; Ikuo Miura; Atsushi Ohshima; Tamio Nishinari; Takashi Nimura; Hidetaka Niitsu; Akira B. Miura
The authors retrospectively evaluated 63 febrile neutropenic episodes in 33 consecutive patients with leukemia who received empiric azole treatment for refractory or relapsing fever that occurred despite broad-spectrum antibiotics. In 8 patients (24%), hepatosplenic abscesses (HSA) developed. To identify the risk factors for the development of HSA, the authors compared various characteristics of febrile episodes in those with and without HSA. The risk factors included relapsed status of leukemia (P = 0.04) and Candida colonization of surveillance cultures from the throat (P = 0.03) and stool (P = 0.03). However, the duration of neutropenia, gastrointestinal symptoms, types of chemotherapy, and leukemia subtypes were not correlated with the development of HSA. Based on these results, the authors identified the high risk group for the development for HSA as patients with relapsed leukemia with fungal colonization of gastrointestinal tract during neutropenia despite empiric antifungal treatment with azoles.
Acta Haematologica | 1993
Ikuo Miura; Tamio Nishinari; Keiko Hashimoto; Takashi Nimura; Takatsu H; Hidetaka Niitsu; Makoto Hirokawa; Akihisa Kuwayama; Shigeki Nishimura; Akira B. Miura
A 20-year-old female with Ph+ acute myelogenous leukemia (M2) associated with t(7;11)(p15;p15) is reported. Bone marrow aspirates were hypercellular with leukemic cells including Auer rods. Chromosome analysis showed t(7;11) and the Ph chromosome. After complete remission, normal karyotype was restored. Normal male karyotypic cells replaced the bone marrow following allogeneic bone marrow transplantation from her brother. On day 358, cytogenetic study at relapse revealed 14q+ as an additional change and clearly showed that the abnormal clone was derived from the patient, because metaphases with XX were all of abnormal karyotype and those with XY were normal.
American Journal of Hematology | 1994
Ikuo Miura; Takatsu H; Akihiko Yamaguchi; Keiko Hashimoto; Takashi Nimura; Tamio Nishinari; Hidetaka Niitsu; Akira B. Miura
The Japanese journal of clinical hematology | 1990
Hidetaka Niitsu; Takatsu H; Ikuo Miura; Akihiko Chubachi; Ito T; Makoto Hirokawa; Yasuyuki Endo; Akira B. Miura; Fukuda M; Sasaki T
Internal Medicine | 1995
Muneyasu Lee; Akihiko Chubachi; Hidetaka Niitsu; Ikuo Miura; Masako Yanagisawa; Makoto Hirokawa; Akira B. Miura
Tohoku Journal of Experimental Medicine | 1989
Makoto Hirokawa; Takatsu H; Hidetaka Niitsu; Tamio Nishinari; Takashi Nimura; Toshihiro Itoh; Akihiko Chubachi; Ikuo Miura; Kosaku Yoshida; Yasuyuki Endo; Akira B. Miura
Thrombosis and Haemostasis | 1984
Yasuyuki Endo; Shigeo Mamiya; Hidetaka Niitsu; Akira B. Miura; Shigeki Nishimura
The Japanese journal of clinical hematology | 1994
Satoh K; Ikuo Miura; Akihiko Chubachi; Ohtani H; Makoto Hirokawa; Hidetaka Niitsu; Akira B. Miura
The Japanese journal of clinical hematology | 1992
Kanno Y; Sakuyama M; Hidetaka Niitsu; Ito T; Lee M; Ohtani H; Nakamoto Y; Akira B. Miura; Akihama T; Yamaguchi A
JAMA Internal Medicine | 1984
Yasukuki Endo; Shigeo Mamiya; Hidetaka Niitsu