Network


Latest external collaboration on country level. Dive into details by clicking on the dots.

Hotspot


Dive into the research topics where Hikoro Matsui is active.

Publication


Featured researches published by Hikoro Matsui.


Journal of Clinical Virology | 2016

Acute encephalopathy in an immunocompromised boy with astrovirus-MLB1 infection detected by next generation sequencing.

Masanori Sato; Makoto Kuroda; Masashi Kasai; Hikoro Matsui; Tetsuhiro Fukuyama; Harutaka Katano; Keiko Tanaka-Taya

We report a case of an immunodeficient 4-year-old boy with acute encephalopathy possibly related to human astrovirus-MLB1 infection. The astrovirus-MLB1 genome was identified in his stool, serum, cerebrospinal fluid, urine, and throat swabs by next generation sequencing. We present additional evidence showing human astroviruses are important infectious agents, regardless of their clades, involving the central nervous system in immunocompromised hosts.


The Journal of Thoracic and Cardiovascular Surgery | 2003

Successful Fontan procedure for asplenia with pulmonary atresia and major aortopulmonary collateral arteries

Kagami Miyaji; Nobuhiro Nagata; Hikoro Matsui; Takashi Miyamoto; Kazuo Kitahori

Asplenia with a single ventricle and major aortopulmonary collateral arteries (MAPCAs) is a rare congenital cardiac anomaly. In this patient group achievement of the Fontan procedure depends on ample rehabilitation of the pulmonary arteries to secure sufficient pulmonary vascular beds and the prevention of progressive pulmonary vascular obstructive disease. Here we report a successful 1-stage bilateral unifocalization of the pulmonary blood supply followed by a staged Fontan procedure in a patient with a univentricular heart and MAPCAs. Clinical Summary The patient was given a diagnosis of asplenia, univentricular heart (right ventricular type), common atrioventricular orifice, pulmonary atresia, bilateral superior vena cavas, total anomalous pulmonary venous connection (intracardiac type), and MAPCAs on the basis of echocardiography and cardiac catheterization. His neonatal aortography showed a small central pulmonary artery (3 mm in diameter) and bilateral multiple MAPCAs (Figure 1, A). The patient’s arterial oxygen saturation (Sa O2) was around 80%, and his pulmonary/systemic blood flow ratio (Qp/Qs) was 1.6 with stable hemodynamics. Subsequent cardiac catheterization at 6 month of age revealed a good-sized central pulmonary artery (Figure 1, B) and 5 large MAPCAs. His SaO2 was approximately 87%, and his Qp/Qs had increased to 3.7. At 1 year of age, he underwent a primary complete unifocalization of his bilateral pulmonary arteries, total anomalous pulmonary venous connection repair for progressive pulmonary venous obstruction (Figure 2), and a left modified Blalock-Taussig shunt (polytetrafluoroethylene [PTFE],* 5 mm). The postoperative course was uneventful except for transient bilateral phrenic nerve palsy. He subsequently did well, while becoming increasingly cyanotic. A catheterization at 2 years of age revealed peripheral pulmonary stenosis, low pulmonary vascular resistance (1.2 Wood units), and normal pulmonary blood flow (Qp/Qs 1.0). The patient then underwent a bilateral bidirectional cavopulmonary shunt and take down of his left modified Blalock-Taussig shunt without cardiopulmonary bypass. This postoperative course was also uneventful, with an SaO2 of 85% and superior vena caval pressure of 10 mm Hg. Eight months after the bilateral bidirectional cavopulmonary shunt, a cardiac catheterization was performed, demonstrating good-shaped pulmonary arteries (Figure 3), low pulmonary vascular resistance (1.4 R*U), low pulmonary artery pressure (mean, 10 mm Hg), and low pulmonary blood flow (Qp/Qs 0.8). Two weeks before definitive surgical intervention, he underwent balloon angioplasty for peripheral pulmonary stenoses and coil embolization of aortopulmonary collateral arteries. At 3 years of age, a fenestrated modified Fontan procedure was performed. An 18-mm PTFE tube graft with a 4-mm PTFE tube graft anastomosed in end-to-side fashion was used for the extracardiac total cavopulmonary connection. The 4-mm PTFE tube graft was anastomosed to the common atrium as a fenestration. The patient was hemodynamically stable intraoperatively, with superior vena caval and inferior vena caval pressures of 11 mm Hg, a common atrial pressure of 4 mm Hg, and an SaO2 of 94%. The patient returned to the cardiovascular intensive care unit in stable condition and was extubated 3 hours after the operation. His postoperative course was uneventful. He was transferred to the general ward on the first postoperative day and discharged home 13 days later without any complications. Three months after the Fontan procedure, another cardiac catheterization was performed, demonstrating a spontaneously occluded tube graft fenestration, an Sa O2 of 96%, low pulmonary artery pressure (mean, 12 mm Hg), and excellent Fontan circulation.


Pediatric Cardiology | 2007

Quantification of Right and Left Ventricular Volumes in Children with Congenital Heart Disease by Multidetector-Row Computed Tomography

Hikoro Matsui; Satoshi Yasukochi; Keiji Haseyama; Sachie Kaneko; Gengi Satomi

Multidetector-row computed tomography (MDCT) of the heart is a new diagnostic approach for the quantitative evaluation of the coronary artery in adults. However, in children, the quantitative analysis of each cardiac chamber has not been established. We attempt to clarify the feasibility and validation of ECG-gated MDCT as a quantitative diagnostic tool to assess the right and left ventricular volume in children. The study consisted of 16 patients who had definite right and left ventricle. After obtaining multislice images by MDCT, we measured the end diastolic volume of both the right and the left ventricle by direct calculation of the region of interest and calculation from the projected image of three-dimensional reconstruction by traditional formulas. The correlation between the two calculations for both ventricles is excellent (r = 0.99 for LV and 0.94 for RV, respectively). The correlations for ventricular volume between calculation of catheterization and calculation of MDCT is also good (r = 0.99 for LV 0.99 for RV, respectively). Volume measurement by ECG-gated MDCT of the right and left ventricles is well correlated with that by catheterization in children and can reduce the necessity for cardiac catheterization.


World Journal for Pediatric and Congenital Heart Surgery | 2011

Second-Stage Palliation After Bilateral Pulmonary Artery Bands for HLHS and its Variants—Which is Better, Modified Norwood or Norwood Plus Bidirectional Glenn?

Takahiko Sakamoto; Yorikazu Harada; Yoshimichi Kosaka; Kentaro Umezu; Satoshi Yasukochi; Kiyohiro Takigiku; Hikoro Matsui; Nao Inoue

Background. The purpose of this study was to evaluate the surgical outcomes and pulmonary artery (PA) development associated with a new strategy wherein the modified Norwood (N) procedure is performed at 1-2 months after bilateral pulmonary artery banding (PAB). Methods. Between January 2008 and February 2010, 16 patients underwent Norwood-type operation after previous bilateral PAB. For analysis, patients were divided into two groups. Group I (n = 11) underwent modified Norwood procedure with either right modified Blalock Taussig (RMBT) shunt (n = 4) or right ventricle to pulmonary artery (RV-PA) conduit (n = 7). Group II (n = 5) underwent Norwood procedure plus bidirectional Glenn anastomosis. Diagnoses were hypoplastic left heart syndrome in 6 and its variants in 10. Results. There was no surgical death and no late death. Pulmonary artery interventions were performed at the time of the Norwood procedure in 27% in Group I and in 100% in Group II (p < 0.05). Additional PA interventions were performed during the period of follow-up in 4 cases in Group I (36.4%), and in 4 cases in Group II (80.0%). Additional Blalock Taussig shunts were performed in 7 patients, resulting in significant increase in PA index. In all, four patients have reached total cavopulmonary connection, and one has undergone biventricular repair. Eight patients in Group I and one patient in II Group reached bidirectional Glenn anastomosis. In Gp II, two patients showed LPA narrowing or obstruction with PA index of 80 ± 12 mm2/m2. Conclusions. Regarding the second-stage palliation after bilateral PAB, modified Norwood procedure with either RMBT or RV-PA conduit has some advantages compared with Norwood plus BDG with respect to subsequent pulmonary artery development. Additional BT shunt may contribute to PA development, even in the patients with Norwood procedure with RV-PA conduit.


Intensive Care Medicine | 2015

Transhepatic diaphragm echography for diaphragm paralysis in infants.

Hikoro Matsui; Masatomo Kitamura; Norimasa Kurosaka; Hitoshi Honma

H. Matsui ()) M. Kitamura N. Kurosaka H. Honma Department of Pediatric Intensive Care, Nagano Children’s Hospital, 3100, Toyoshina, Azumino City, Nagano 399-8288, Japan e-mail: [email protected] Tel.: ?81-(0)263-73-6700 Diagnosis of diaphragm paralysis, occasionally occurring in post-cardiac surgery of infants with congenital heart disease, is important for post-operative respiratory care because abdominal respiration is dominant in neonates and infants. Fluoroscopy is a standard examination for assessing diaphragmatic motion. However, echography is a useful bedside tool in daily clinics to check diaphragm motion, but measuring both sides simultaneously is difficult. The transhepatic coronal view, obtained with a lowfrequency echo probe, is a specific view that demonstrates right and left diaphragm motion simultaneously (Fig. 1). This technique is highly applicable for neonates and infants because the penetration of ultrasound, and the


Pediatrics International | 2014

Decreased granulomatous reaction by polyurethane-coated stent in the trachea.

Hikoro Matsui; Takehiko Hiroma; Hisaya Hasegawa; Yoshifumi Ogiso

Reducing granulomatous reaction for stent implantation is important for the treatment of tracheobronchomalacia because formation of granuloma leads to refractory complication causing further respiratory distress. The purpose of this study was to clarify granulomatous reaction of newly innovated coated stents compared to non‐coated metal stents.


Pediatrics International | 2018

Unknown mass on chest radiography: Morgagni hernia identified on ultrasonography

Takahiro Saima; Masanori Sato; Yuichiro Miyake; Hikoro Matsui

A 3-month-old girl with a double-outlet right ventricle and other minor anomalies, was admitted to hospital because of respiratory impairment, demonstrated by retractive breathing, without other signs of heart failure. Her condition required critical care, including intubation and mechanical ventilation. Bronchofiberscopy indicated tracheobronchomalacia, whereas chest radiography showed a tumor-like consolidation in the right lower lung area (Fig. 1). Although routine ultrasonography could not provide details of the mass, trans-hepatic diaphragm ultrasonography showed a right anterior diaphragmatic defect (Fig. 2, white arrowheads) with a herniated liver (Fig. 2, arrow), while the left diaphragm was normal (black arrowheads). Congenital Morgagni hernia (CMH) was suspected, and magnetic resonance imaging (MRI) subsequently confirmed this diagnosis. Despite surgical repair of the hernia, which included laparotomy and primary closure of the diaphragmatic defect, the patient still required non-invasive positive pressure ventilation after extubation because of the tracheobronchomalacia. Congenital Morgagni hernia is a relatively rare malformation, accounting for 1–5% of congenital diaphragmatic hernias (CDH) in infants. Although most CDH are prenatally diagnosed on ultrasonography and are accompanied by a severe clinical course after birth, CMH can present with non-specific symptoms or may be asymptomatic, and is occasionally diagnosed in adults. Many cases of CMH have other associated anomalies, including congenital heart disease. While computed tomography and MRI are routinely used in the diagnosis of CMH, ultrasonography is a useful tool for detecting diaphragmatic defects. We achieved the trans-hepatic coronal view of a coronal plane from the upper flank to the xiphoid process by using a low-frequency sector probe that provides clear images of both the right and left diaphragms (1–5 MHz sector probe in a CX50 ultrasonography machine; Phillips Ultrasound, Bothell, WA, USA). This technique is appropriate for neonates and infants because of the penetration ability of ultrasonography. Congenital Morgagni hernia is clinically unique as compared with other CDH, and chance appearance of an unknown mass on chest radiography for other conditions is possible, similar to that in the present case. Ultrasonography is useful for detecting diaphragmatic defects in the neonatal period and early infancy.


Childs Nervous System | 2018

Prognostic factors of acute neurological outcomes in infants with traumatic brain injury

Shunsuke Amagasa; Satoshi Tsuji; Hikoro Matsui; Satoko Uematsu; Takashi Moriya; Kosaku Kinoshita

PurposeThe purpose of this study is to clarify risk factors for poor neurological outcomes and distinctive characteristics in infants with traumatic brain injury.MethodsThe study retrospectively reviewed data of 166 infants with traumatic intracranial hemorrhage from three tertiary institutions in Japan between 2002 and 2013. Univariate and multivariate analyses were used to identify clinical symptoms, vital signs, physical findings, and computed tomography findings associated with poor neurological outcomes at discharge from the intensive care unit.ResultsIn univariate analysis, bradypnea, tachycardia, hypotension, dyscoria, retinal hemorrhage, subdural hematoma, cerebral edema, and a Glasgow Coma Scale (GCS) score of ≤ 12 were significantly associated with poor neurological outcomes (P < 0.05). In multivariate analysis, a GCS score of ≤ 12 (OR = 130.7; 95% CI, 7.3–2323.2; P < 0.001), cerebral edema (OR = 109.1; 95% CI, 7.2–1664.1; P < 0.001), retinal hemorrhage (OR = 7.2; 95% CI, 1.2–42.1; P = 0.027), and Pediatric Index of Mortality 2 score (OR = 1.6; 95% CI, 1.1–2.3; P = 0.018) were independently associated with poor neurological outcomes. Incidence of bradypnea in infants with a GCS score of ≤ 12 (25/42) was significantly higher than that in infants with GCS score of > 12 (27/90) (P = 0.001).ConclusionsInfants with a GCS score of ≤ 12 are likely to have respiratory disorders associated with traumatic brain injury. Physiological disorders may easily lead to secondary brain injury, resulting in poor neurological outcomes. Secondary brain injury should be prevented through early interventions based on vital signs and the GCS score.


Brain & Development | 2018

Early prognostic factors for acute encephalopathy with reduced subcortical diffusion

Tetsuhiro Fukuyama; Shouko Yamauchi; Shunsuke Amagasa; Yuka Hattori; Taku Sasaki; Hideko Nakajima; Yuko Takei; Jiu Okuno; Yuka Misawa; Noboru Fueki; Masatomo Kitamura; Hikoro Matsui; Yuji Inaba; Shinichi Hirabayashi

OBJECTIVE The aim of this study was to determine the prognostic factors for acute encephalopathy with reduced diffusion (AED) during the acute phase through retrospective case evaluation. METHODS The participants included 23 patients with AED. The diagnosis of AED was based on their clinical course and radiological findings. We divided the patients into severe and non-severe groups based on the neurodevelopmental outcome. The severe group included seven patients (median age, 21 months; range, 6-87 months) and the non-severe group included 16 patients (19 months, 9-58 months). Clinical symptoms, laboratory data and electroencephalogram (EEG) findings within 48 h from the initial seizure onset were compared between the two groups to identify neurological outcome predictors. RESULTS The incidence of coma 12-24 h after onset, serum creatinine (Cr) levels within 2 h after onset, maximum aspartate aminotransferase (AST) levels within 24 h after onset, and the rate of electrographic seizures in EEG were significantly higher in the severe group (Coma, 80%; Cr, 0.40 mg/dl, 0.37-0.73; AST, 363 IU/L, 104-662; electrographic seizures, 80%) than the non-severe group (Coma, 0%; Cr, 0.29 mg/dL, 0.19-0.45; AST, 58.5 IU/L, 30-386; electrographic seizures, 0%). CONCLUSIONS Coma 12-24 h after onset, elevation of Cr levels within 2 h after onset, elevation of AST levels within 24 h after onset, and non-convulsive status epileptics (NCSE) in comatose patients were early predictors of severe AED. Patients in a coma after a febrile seizure should be checked for NCSE signs in EEG to terminate NCSE without delay.


Acute medicine and surgery | 2018

Characteristics distinguishing abusive head trauma from accidental head trauma in infants with traumatic intracranial hemorrhage in Japan

Shunsuke Amagasa; Hikoro Matsui; Satoshi Tsuji; Satoko Uematsu; Takashi Moriya; Kosaku Kinoshita

To identify markers for detecting abusive head trauma (AHT) and its characteristics in the Japanese population.

Collaboration


Dive into the Hikoro Matsui's collaboration.

Top Co-Authors

Avatar

Satoshi Yasukochi

Boston Children's Hospital

View shared research outputs
Top Co-Authors

Avatar

Gengi Satomi

Memorial Hospital of South Bend

View shared research outputs
Top Co-Authors

Avatar

Yorikazu Harada

Boston Children's Hospital

View shared research outputs
Top Co-Authors

Avatar

Kiyohiro Takigiku

Boston Children's Hospital

View shared research outputs
Top Co-Authors

Avatar

Masatomo Kitamura

Boston Children's Hospital

View shared research outputs
Top Co-Authors

Avatar

Shunsuke Amagasa

Boston Children's Hospital

View shared research outputs
Top Co-Authors

Avatar

Takahiko Sakamoto

Boston Children's Hospital

View shared research outputs
Top Co-Authors

Avatar

Yoshifumi Ogiso

Boston Children's Hospital

View shared research outputs
Top Co-Authors

Avatar

Masanori Sato

Boston Children's Hospital

View shared research outputs
Top Co-Authors

Avatar

Masashi Kasai

Boston Children's Hospital

View shared research outputs
Researchain Logo
Decentralizing Knowledge