Himatkumar V. Patel

Facile synthesis of hydrazonyl halides by reaction of hydrazones with N-halosuccinimide-dimethyl sulfide complex

Abstract A new and convenient method is described for the synthesis of hydrazonyl halides. Hydrazones on treatment with N -chlorosuccinimide-dimethyl sulfide complex result in the formation of the corresponding hydrazonyl chlorides in good yields. Similarly, treatment of hydrazones with N -bromosuccinimide-dimethyl sulfide complex gives the corresponding hydrazonyl bromide under extremely mild conditions.

Concise and Efficient Synthesis of 1H-Pyrazoles: Reaction of [Hydroxy(tosyloxy)iodo]benzene with Ethyl 2,3-Dioxobutanoate-2-arylhydrazones

Abstract Ethyl 2,3-dioxobutanoate-2-arylhydrazones 1 on treatment with [hydroxy(tosyloxy)iodo]benzene 2 at reflux temperature and followed by heating in the presence of N-ethyldiisopropylamine afforded the cyclized ethyl 1-aryl-4-hydroxy-1H-3-pyrazolecarboxylates 4 in good yield.

Reaction of Triethyl Phosphonoacetate Anion with Phenylhydrazones: A New Method for the Preparation of 3(2H)-Pyridazinones

Abstract Various 5,6-disubstituted-2-phenyl-3(2H)-pyridazinones 4 have been synthesised by reacting triethyl phosphonoacetate anion with monophenylhydrazone of 1,2-dicarbonyl compounds 2.

A New and Convenient Synthesis of 3(2H)-Pyridazinones by Reacting Carbanion of Ethyl Trimethylsilylacetate with Phenylhydrazones

Abstract A one-pot synthesis of 5,6-disubstituted-2-phenyl-3(2H)-pyridazinones 4 is achieved on treatment of carbanion of ethyl trimethlsiylacetate with phenylhydrazones of 1,2-dicarbonyl compounds 1.

Reaction of 2, 3, 4-pentantrione-3-arylhydrazones with N, N-dimethylhydrazine: Formation of substituted 1H-pyrazoles via demethylation

Abstract A novel one-step synthesis of 4-arylazo-1H-1, 3, 5-trimethylpyrazoles is accomplished by reaction of N, N-dimethylhydrazine with 2, 3, 4-pentantrione-3-arylhydrazones via an unusual demethylation.