Hiroaki Tsuji

Ruthenium-Catalyzed Regio- and Enantioselective Allylic Amination of Racemic 1-Arylallyl Esters

The regio- and enantioselective allylic amination of racemic monosubstituted allylic esters, such as 1-arylallyl acetates, with cyclic secondary amines has been accomplished. The RuCl3/(S,S)-ip-pybox catalyst system has effectively catalyzed the reaction to afford the enantiomerically enriched branch-type allylic amines with perfect regioselectivity and high enantioselectivity.

Nickel-Catalyzed Asymmetric Propargylic Amination of Propargylic Carbonates Bearing an Internal Alkyne Group

We have achieved the nickel-catalyzed asymmetric propargylic amination of propargylic carbonates bearing an internal alkyne group. A wide variety of propargylic carbonates and N-methylaniline derivatives were tolerated under the reaction conditions, providing the corresponding chiral propargylic amines in up to 97% yield with up to 97% ee.

Sonogashira Coupling with Bimetallic Pd–Au Nanoparticles on Carbon

103 C . R OS S Y , J . M A J I M E L , E . F O U Q UE T, C . D E L A C Ô T E, M . B O U J T I T A , C . L A B R U G È R E, M . TR É G UE RD E L A P I E R R E , * F. X . FE L PI N * ( U NI VE R S I T É D E N A N T E S , UN I V E R S I T É D E B O R D E A U X , TA L E N C E A N D U N I V E R S I T É D E B O R D E A U X , P E S SA C , FR A N C E ) Stabilisation of Carbon-Supported Palladium Nanoparticles through the Formation of an Alloy with Gold: Application to the Sonogashira Reaction Chem. Eur. J. 2013, 19, 14024–14029.