Hiromi Sasaki
Tohoku Pharmaceutical University
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Publication
Featured researches published by Hiromi Sasaki.
Journal of Pharmacy and Pharmacology | 1995
Shuichi Takeda; Tomoko Isono; Yoko Wakui; Yutaka Matsuzaki; Hiromi Sasaki; Sakae Amagaya; Masao Maruno
The absorption and excretion of paeoniflorin after intravenous and oral administration was studied in rats to evaluate the significance of paeoniflorin in the pharmacological action of Paeony root.
Journal of Chromatography B: Biomedical Sciences and Applications | 1992
Yoko Wakui; Erika Yanagisawa; Emiko Ishibashi; Yutaka Matsuzaki; Shuichi Takeda; Hiromi Sasaki; Masaki Aburada; Tsutomu Oyama
A rapid and sensitive method, using electrochemical detection, has been developed for the determination of baicalin and baicalein, the flavonoid of Scutellariae radix, in rat plasma. Following separation by high-performance liquid chromatography, baicalin and baicalein were oxidized at a glassy carbon electrode to permit selective electrochemical detection. Absolute detection limits were found to be 5 ng/ml from 50 microliters of plasma for baicalin and 2 ng/ml from 100 microliters of plasma for baicalein. The resulting assays were suitable for pharmacokinetic studies of baicalin and baicalein in rats.
Chemical & Pharmaceutical Bulletin | 2002
Koichi Machida; Hiromi Sasaki; Takeyoshi Iijima; Masao Kikuchi
Journal of Toxicological Sciences | 1998
Toshihiko Yanagisawa; Shunichi Maemura; Hiromi Sasaki; Toru Endo; Minoru Okada; Philip W. East; David M. Virgo; Dianne M. Creasy
Journal of Chromatography B: Biomedical Sciences and Applications | 1990
Shuichi Takeda; Hiromasa Ono; Yoko Wakui; Akitoshi Asami; Yutaka Matsuzaki; Hiromi Sasaki; Masaki Aburada; Eikichi Hosoya
Chemical & Pharmaceutical Bulletin | 1988
Yukinobu Ikeya; Heihachiro Taguchi; Hiroshi Mitsuhashi; Hiromi Sasaki; Tamae Matsuzaki; Masaki Aburada; Eikichi Hosoya
Chemical & Pharmaceutical Bulletin | 1990
Yukinobu Ikeya; Hiroshi Mitsuhashi; Hiromi Sasaki; Yutaka Matsuzaki; Tamae Matsuzaki; Eikichi Hosoya
Drug Metabolism and Pharmacokinetics | 1992
Yutaka Matsuzaki; Tamae Matsuzaki; Shuichi Takeda; Hiromi Sasaki; Masaki Aburada; Eikichi Hosoya; Tsutomu Oyama; Yoshio Esumi; Yoshitaka Jin; Hisako Ishikawa; Tetsuyoshi Yokoshima
Yakugaku Zasshi-journal of The Pharmaceutical Society of Japan | 1991
Yutaka Matsuzaki; Tamae Matsuzaki; Shuichi Takeda; Sachiko Koguchi; Yukinobu Ikeya; Hiroshi Mitsuhashi; Hiromi Sasaki; Masaki Aburada; Eikichi Hosoya; Tsutomu Oyama
Drug Metabolism and Pharmacokinetics | 1992
Yutaka Matsuzaki; Tamae Matsuzaki; Shuichi Takeda; Hiromi Sasaki; Masaki Aburada; Eikichi Hosoya; Tsutomu Oyama; Yoshio Esumi; Yoshitaka Jin; Hisako Ishikawa; Tetsuyoshi Yokoshima
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