Hiromitsu Iwata
Nippon Soda Co., Ltd.
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Publication
Featured researches published by Hiromitsu Iwata.
Journal of The Chemical Society, Chemical Communications | 1991
Takashi Nakatsuka; Hiromitsu Iwata; Rie Tanaka; Seiichi Imajo; Masaji Ishiguro
(3S,4R,1′R)-4-Acetoxy-3-(1′-tert-butyldimethylsilyloxyethyl)-azetidin-2-one 8, an important intermediate for the synthesis of penem and carbapenem antibiotics, was synthesized from (R)-butane-1,3-diol 1, using chlorosulphonyl isocyanate for the formation of β-lactam ring in which a significant solvent effect on the ratio of diastereoisomers 6a and 6b was observed; copper(II) acetate rather than the poisonous mercury(II) acetate was used to convert the phenylthio group of compound 6a to acetoxy.
Journal of The Chemical Society, Chemical Communications | 1991
Hiromitsu Iwata; Rie Tanaka; Seiichi Imajo; Yoshiaki Oyama; Masaji Ishiguro
5,6-trans-Penem compounds were photochemically transformed via isomerisation at C(5) to 5,6-cis-penems, the structures of which were confirmed by spectroscopic and X-ray crystallographic analysis.
The Journal of Antibiotics | 1988
Masaji Ishiguro; Hiromitsu Iwata; Takashi Nakatsuka; Rie Tanaka; Yoko Maeda; Tatsuro Nishihara; Teruhisa Noguchi; Takeshi Nishino
Journal of Biochemistry | 1989
Hideki Adachi; Ichiro Kubota; Nobutaka Okamura; Hiromitsu Iwata; Masafumi Tsujimoto; Hiroshi Nakazato; Tatsuro Nishihara; Teruhisa Noguchi
Archive | 1990
Masaji Ishiguro; Hiromitsu Iwata; Takashi Nakatsuka
Archive | 1986
Masaji Ishiguro; Hiromitsu Iwata; Takashi Nakatsuka
The Journal of Antibiotics | 1990
Hiromitsu Iwata; Rie Tanaka; Masaji Ishiguro
Archive | 1989
Masaji Ishiguro; Hiromitsu Iwata; Takashi Nakatsuka; Yasuo Yamada
Archive | 1987
Masaji Ishiguro; Hiromitsu Iwata; Rie Tanaka
Archive | 1990
Masaji Ishiguro; Hiromitsu Iwata; Takashi Nakatsuka; Masashi Nakajima; Yasuo Yamada; Junichi Doi; Masayoshi Fujimaru