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Hiroshi Hosono

Gifu Pharmaceutical University

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Publication

Featured researches published by Hiroshi Hosono.

Nucleosides, Nucleotides & Nucleic Acids | 1992

Synthesis of Thymidine Derivatives 3′-Modified with a Polar Three-Atom Group as Potential Anti-HIV-1 Agents

Kosaku Hirota; Hiroshi Hosono; Yukio Kitade; Yoshifumi Maki; Chung K. Chu; Raymond F. Schinazi; Osamu Muraoka

Abstract 3′-Modified thymidine analogs, such as 3′-O-[(methylthio)thio-carbonyl]thymidine (4), 3′-O-thiocarbamoylthymidine (7), and N-(3′-deoxy-thymidin-3′-y1)phosphoramidates (9a, b), were synthesized from thymidine derivatives (1), (5), and (8), respectively, as potential anti-human immunodeficiency virus type 1 (HIV-1) agents. No significant activity against HIV-1 was, however, observed with any of these compounds.

Chemical & Pharmaceutical Bulletin | 1994

Novel and Potent Aldose Reductase Inhibitors : 4-Benzyl- and 4-(Benzothiazol-2-ylmethyl)-3, 4-dihydro-3-oxo-2H-1, 4-benzothiazine-2-acetic Acid Derivatives

Tomoji Aotsuka; Hiroshi Hosono; Toshio Kurihara; Yoshiyuki Nakamura; Tetsuo Matsui; Fujio Kobayashi

Chemical & Pharmaceutical Bulletin | 1990

Synthesis and anti-human immunodeficiency virus (HIV-1) activity of 3'-deoxy-3'-(triazol-1-yl)thymidines and 2',3'-dideoxy-3'-(triazol-1-yl)uridines and inhibition of reverse transcriptase by their 5'-triphosphates.

Kosaku Hirota; Hiroshi Hosono; Yukio Kitade; Yoshifumi Maki; Chung K. Chu; Raymond F. Schinazi; Hideo Nakane; Katsuhiko Ono

Archive | 1994

Quinoline-3-acetic acid derivative, process for production thereof and use thereof

Tomoji Aotsuka; Toshiyuki Nishio; Hiroshi Hosono; Yoshiyuki Nakamura; Tetsuo Matsui; Hiromichi Ishikawa

Archive | 1994

BENZOTHIAZOLE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF

Takema Hase; Takahiro Kumonaka; Chikako Shimizu; Hiroshi Hosono; Tomoji Aotsuka; Yoshiyuki Nakamura; Tetsuo Matsui; Hiromichi Ishikawa

Archive | 1994

Succinamic acid compound, process for producing the same, and use thereof

Hiroshi Hosono; Toshiyuki Nishio; Hiromichi Ishikawa; Yoshiyuki Nakamura; Tetsuo Matsui

Archive | 1991

1,4-benzothiazine-2-acetic acid derivatives

Tomoji Aotsuka; Hiroshi Hosono; Toshio Kurihara; Yoshiyuki Nakamura; Tetsuo Matsui; Fujio Kobayashi

Archive | 1994

BERNSTEINSÄUREMONOAMIDVERBINDUNG, VERFAHREN ZUR DEREN HERSTELLUNG UND DEREN VERWENDUNG

Hiroshi Hosono; Toshiyuki Nishio; Hiromichi Ishikawa; Yoshiyuki Nakamura; Tetsuo Matsui

Archive | 1994

Succinamic, process for their preparation and their use

Hiroshi Hosono; Toshiyuki Nishio; Hiromichi Ishikawa; Yoshiyuki Nakamura; Tetsuo Matsui

Archive | 1994

Benzothiazol-derivate, verfahren zur herstellung sowie anwendungen Benzothiazole derivatives, processes for the preparation and applications

Takema Hase; Takahiro Kumonaka; Chikako Shimizu; Hiroshi Hosono; Tomoji Aotsuka; Yoshiyuki Nakamura; Tetsuo Matsui; Hiromichi Ishikawa

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Yoshiyuki Nakamura

University of Shizuoka

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Tetsuo Matsui

Astellas Pharma

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Kosaku Hirota

Gifu Pharmaceutical University

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Yoshifumi Maki

Gifu Pharmaceutical University

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Yukio Kitade

Gifu Pharmaceutical University

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Chung K. Chu

University of Georgia

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Raymond F. Schinazi

Emory University

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Katsuhiko Ono

Okayama University

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Osamu Muraoka

Kindai University

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