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Dive into the research topics where Hiroto Araki is active.

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Featured researches published by Hiroto Araki.


Transfusion | 2015

Ex vivo expansion of human mobilized peripheral blood stem cells using epigenetic modifiers

Santosh L. Saraf; Hiroto Araki; Benjamin Petro; Youngmin Park; Simona Taioli; Kazumi Yoshinaga; Emre Koca; Damiano Rondelli; Nadim Mahmud

Epigenetic modifications likely control the fate of hematopoietic stem cells (HSCs). The chromatin‐modifying agents (CMAs), 5‐aza‐2′‐deoxycytidine (5azaD) and trichostatin A (TSA), have previously been shown to expand HSCs from cord blood and marrow. Here we assessed whether CMA can also expand HSCs present in growth factor–mobilized human peripheral blood (MPB).


Blood | 2004

Modification of hematopoietic stem cell fate by 5aza 2′deoxycytidine and trichostatin A

Mohammed Milhem; Nadim Mahmud; Donald Lavelle; Hiroto Araki; Joseph DeSimone; Yogen Saunthararajah; Ronald Hoffman


Blood | 2007

Chromatin-modifying agents permit human hematopoietic stem cells to undergo multiple cell divisions while retaining their repopulating potential

Hiroto Araki; Kazumi Yoshinaga; Piernicola Boccuni; Yan Zhao; Ronald Hoffman; Nadim Mahmud


Biology of Blood and Marrow Transplantation | 2014

Differential effects of epigenetic modifiers on the expansion and maintenance of human cord blood stem/progenitor cells.

Nadim Mahmud; Benjamin Petro; Sudhakar Baluchamy; Xinmin Li; Simona Taioli; Donald Lavelle; John G. Quigley; Montha Suphangul; Hiroto Araki


Experimental Hematology | 2009

Cord blood stem cell expansion is permissive to epigenetic regulation and environmental cues

Hiroto Araki; Sudhakar Baluchamy; Kazumi Yoshinaga; Benjamin Petro; Sakina M. Petiwala; Ritesh Parajuli; Mohammed Milhem; Donald Lavelle; Joseph DeSimone; Nadim Mahmud


Blood | 2006

Allogeneic T cells induce rapid CD34+ cell differentiation into CD11c+CD86+ cells with direct and indirect antigen-presenting function

Javaneh Abbasian; Dolores Mahmud; Nadim Mahmud; Sandeep Chunduri; Hiroto Araki; Pavan Reddy; Ronald Hoffman; Mario Arpinati; James L.M. Ferrara; Damiano Rondelli


Archive | 2006

Alteration of Hematopoietic Stem Cell Fates by Chromatin-Modifying Agents

Nadim Mahmud; Mohammed Milhem; Hiroto Araki; Ronald Hoffman


Blood | 2008

Possible Epigenetic Regulation of Functionally Opposing Groups of Genes Involved in Ex Vivo Expansion of Cord Blood Stem Cells

Sudhakar Baluchamy; Benjamin Petro; Hiroto Araki; Valerie Lindgren; Nadim Mahmud


Blood | 2011

Ex Vivo Expansion of Human Mobilized Peripheral Blood Stem Cells Using Epigenetic Modifiers

Santosh L. Saraf; Hiroto Araki; Benjamin Petro; Kazumi Yoshinaga; Simona Taioli; Amer Sidani; John G. Quigley; Damiano Rondelli; Nadim Mahmud


Blood | 2008

Expansion of Cord Blood Stem Cells Mediated by Epigenetic Mechanisms Remain Permissive to External Environmental Cues

Hiroto Araki; Kazumi Yoshinaga; Sudhakar Baluchamy; Benjamin Petro; Donald Lavelle; Joseph DeSimone; Naoyuki Katayama; Nadim Mahmud

Collaboration


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Nadim Mahmud

University of Illinois at Chicago

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Ronald Hoffman

University of Illinois at Chicago

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Benjamin Petro

University of Illinois at Chicago

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Kazumi Yoshinaga

University of Illinois at Chicago

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Damiano Rondelli

University of Illinois at Chicago

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Donald Lavelle

University of Illinois at Chicago

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Mohammed Milhem

University of Illinois at Chicago

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Sudhakar Baluchamy

University of Illinois at Chicago

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Joseph DeSimone

University of Illinois at Chicago

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Simona Taioli

University of Illinois at Chicago

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