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Dive into the research topics where Hiroto Chikaura is active.

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Featured researches published by Hiroto Chikaura.


Surface Topography: Metrology and Properties | 2015

Textured bearing surface in artificial joints to reduce macrophage activation

Yoshitaka Nakanishi; Naoki Nishi; Hiroto Chikaura; Yuta Nakashima; Hiromasa Miura; Hidehiko Higaki; Hiroshi Mizuta; Yukihide Iwamoto; Yukio Fujiwara; Yoshihiro Komohara; Motohiro Takeya

Micro slurry-jet erosion has been proposed as a precision machining technique for the bearing surfaces of artificial joints in order to reduce the total amount of polyethylene wear and to enlarge the size of the wear debris. The micro slurry-jet erosion method is a wet blasting technique which uses alumina particles as the abrasive medium along with compressed air and water to create an ideal surface. Pin-on-disc wear tests with multidirectional sliding motion on the textured surface of a alloy counterface for polyethylene resulted in both a reduction of wear as well as enlargement of the polyethylene debris size. In this study, primary human peripheral blood mononuclear phagocytes were incubated with the debris, and it was elucidated that the wear debris generated on the textured surface regulated secretion of the proinflammatory cytokines IL-6 and TNF-α, indicating a reduction in the induced tissue reaction and joint loosening.


international power electronics and motion control conference | 2014

Development of a new type of seal system for use in ocean current or tidal power generation

Hiroto Chikaura; Yuichi Oka; Yuta Nakashima; Yoshitaka Nakanishi

Ocean current or tidal power is a promising renewable resource. For the generation of electricity from them, it is important to construct waterproof system with reducing mechanical energy loss. However, there is no appropriate sealing system that is completely waterproof and low friction. So, we developed a new type of seal system for using in ocean current and tidal power generation. We introduced seal lips made of a polyvinyl formal (PVF). PVF lips were attached to a rotating shaft, and a non-Newtonian, aqueous solution of 3.0wt% polyethylene glycol (PEG) with a molecular weight of 2.0 million was applied as lubrication. This sealing system was low water leakage, less than 0.05ml/h, was recorded throughout the experiment. Mean frictional torque was lower than those with a mechanical seal or an oil seal, both of which are generally used for industrial components. Furthermore, frictional torque was stable, and friction was independent of the speed of the rotating shaft.


Biosurface and Biotribology | 2016

Effect of particle size on biological response by human monocyte-derived macrophages

Hiroto Chikaura; Yuta Nakashima; Yukio Fujiwara; Yoshihiro Komohara; Motohiro Takeya; Yoshitaka Nakanishi


The Proceedings of the Bioengineering Conference Annual Meeting of BED/JSME | 2016

2G36 Relationship between biological response and morphological aspect of wear debris generated from ultra-high molecular weight polyethylene used in artificial joint

Riku Yoshioka; Haruyuki Masaoka; Hiroto Chikaura; Naoki Nishi; Yuta Nakashima; Yukio Fujiwara; Yoshihiro Komohara; Motohiro Takeya; Hiroshi Mizuta; Hidehiko Higaki; Yoshitaka Nakanishi


The Proceedings of Conference of Kyushu Branch | 2016

H-09 Effects of participate stimulation on activity of human monocyte-derived macrophages

Hiroto Chikaura; Naoki Nishi; Riku Yoshioka; Shin Sakuraba; Yuta Nakashima; Yoshitaka Nakanishi


The Proceedings of Conference of Kyushu Branch | 2016

H-08 Influence of surface texturing on wear of ultra-high molecular weight polyethylene in artificial joint

Naoki Nishi; Hiroto Chikaura; Riku Yoshioka; Shin Sakuraba; Yuta Nakashima; Yoshitaka Nakanishi


Journal of Bone and Joint Surgery-british Volume | 2016

THE EFFECT OF TEXTURING CO-CR-MO ALLOY SURFACES UPON UHMWPE WEAR PARTICLE SIZE

Naoki Nishi; Hiroto Chikaura; Katsuki Kuwahata; Toru Matsubara; Yuta Nakashima; Yoshitaka Nakanishi


Journal of Bone and Joint Surgery-british Volume | 2016

PRECISION SURFACE MACHINING OF ARTIFICIAL JOINT BEARING SURFACES TO INHIBIT MACROPHAGE ACTIVATION

Yoshitaka Nakanishi; Naoki Nishi; Hiroto Chikaura; Katsuki Kuwahata; Yuta Nakashima; Kohei Murase; Hiromasa Miura; Hidehiko Higaki; Hiroshi Mizuta; Yukihide Iwamoto


The Proceedings of the Symposium on Micro-Nano Science and Technology | 2015

28pm3-E-8 Capture of Circulating Tumor Cells Using a Nucleic Acid Aptamer-Modified Device

Yuta Nakashima; Yusuke Kitamura; Hiroto Chikaura; Shoji Sasaki; Keiichiro Yasuda; Kenshiro Nakatake; Akiko Tachibana; Masaaki Iwatsuki; Hideo Baba; Toshihiro Ihara; Yoshitaka Nakanishi


The Proceedings of the JSME Conference on Frontiers in Bioengineering | 2015

A202 Influences of wear debris from artificial joints on macrophage activations

Hiroto Chikaura; Naoki Nishi; Riku Yoshioka; Haruyuki Masaoka; Yuta Nakashima; Yukio Fujiwara; Yoshihiro Komohara; Motohiro Takeya; Hiroshi Mizuta; Hidehiko Higaki; Yoshitaka Nakanishi

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