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Dive into the research topics where Hiroyuki Harada is active.

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Featured researches published by Hiroyuki Harada.


Acta Oto-laryngologica | 2014

Predictive value of middle ear aeration before second-stage operation in staged tympanoplasty with soft-wall reconstruction

Yuji Kanazawa; Yasushi Naito; Risa Tona; Keizo Fujiwara; Shogo Shinihara; Masahiro Kikuchi; Hiroshi Yamazaki; Ippei Kishimoto; Hiroyuki Harada

Abstract Conclusion: The extent of middle ear aeration before second-stage canal wall-down (CWD) tympanoplasty was correlated with postoperative middle ear stability. Objective: To evaluate middle ear aeration before second-stage CWD tympanoplasty as a predictor of postoperative re-aeration potential and external auditory canal (EAC) stability in staged CWD tympanoplasty with soft-wall reconstruction (SWR). Methods: Middle ear aeration was evaluated before and at 1 year after the second-stage operation in patients who underwent staged CWD tympanoplasty with SWR for middle ear cholesteatoma. Based on the computed tomography (CT) findings, middle ear aeration was graded as A when the mastoid and tympanic cavities were aerated, B when only the tympanic cavity was aerated, and C in cases with no aeration in the tympanic cavity. We also examined postoperative EAC stability. Results: Forty-one ears were included. In all, 17 of 19 ears (89.5%) with grade A aeration preoperatively maintained grade A aeration postoperatively, while 5 of 18 ears (27.8%) with grade B aeration had grade A aeration, and no ear with grade C aeration had recovered grade A aeration. All ears with grade A aeration preoperatively maintained smooth EACs. EAC retraction requiring additional treatment occurred in five ears with grade B aeration and all ears with grade C aeration.


Acta Oto-laryngologica | 2014

Clinical features of rapidly progressive bilateral sensorineural hearing loss.

Ippei Kishimoto; Hiroshi Yamazaki; Yasushi Naito; Shogo Shinohara; Keizo Fujiwara; Masahiro Kikuchi; Yuji Kanazawa; Risa Tona; Hiroyuki Harada

Abstract Conclusion: Rapidly progressive bilateral sensorineural hearing loss (SNHL) often develops as a symptom of intracranial diseases or systemic vasculitis. For early diagnosis and treatment of these potentially fatal diseases, a history of hearing deterioration within 2 months and associated symptoms may be important. Objectives: To reveal clinical features and causative diseases for rapidly progressive bilateral SNHL. Methods: The inclusion criterion was patients with bilateral progressive SNHL, who had experienced difficulty in daily conversation within 4 days to 1 year after the onset of hearing loss awareness. This study was a retrospective evaluation of 12 patients with rapidly progressive bilateral SNHL who visited our hospital between 2007 and 2011. Results: The causative disease for hearing loss was identified in 11 of 12 patients; intracranial lesions including nonbacterial meningitis, meningeal metastasis of lymphoma, and superficial siderosis in 4 patients, systemic vasculitis in 2, auditory neuropathy spectrum disorder in 1, and an isolated inner ear disorder in 4. Relatively rapid hearing deterioration within 2 months showed a significant association in six patients with an intracranial lesion or systemic vasculitis. Moreover, all these six patients complained of dizziness and/or non-cochleovestibular symptoms such as fever, headache, and/or altered mental state in addition to hearing loss.


Acta Oto-Laryngologica Case Reports | 2017

Two swallowed dentures found in the hypopharynx and rectum of an elderly Japanese woman simultaneously

Ryosuke Yamamoto; Shogo Shinohara; Hiroyuki Harada; Koji Saida; Kazuki Hayashi; Tetsuhiko Michida; Shinji Takebayashi; Keizo Fujiwara; Yasushi Naito

Abstract The aging Japanese population has led to an increase in the number of accidentally swallowed dentures. Therefore, we report the case of an elderly Japanese woman with dementia who accidentally and sequentially swallowed two dentures. The patient presented to our hospital with a diagnosis of a single impacted denture in her hypopharynx although we subsequently identified a second impacted denture in her rectum after taking a careful clinical history. Open surgery was required to remove the second denture from her rectum. This case highlights the importance of carefully considering the patient’s history if there is a possibility of latent swallowed dentures.


Acta Oto-Laryngologica Case Reports | 2017

Two cases with an interseptal sinus cell mucocele: The different mechanisms of the development varying in the time of the onset

Fumihiko Kuwata; Shogo Shinohara; Hiroyuki Harada; Ippei Kishimoto; Atsushi Suehiro; Keizo Fujiwara; Yasushi Naito

Abstract Intersinus septal cells (ISSC) are defined as cells confined to the thin septum separating the frontal sinuses. In 2008, Som et al. first described four cases with a mucocele proved to have arisen in ISSC. Here, we report two cases with a mucocele in ISSC, representing the second report to appear in the English literature. Case 1 involved a mucocele in the center of the frontal lesion with rudimentary bilateral frontal sinuses, which suggested that the ISSC mucocele occurred during very early development of the frontal sinuses. Case 2 concerned a mucocele in the unilocular frontal sinus invading the left orbit. The frontal sinus septum was destroyed with partial ‘Y’-shaped remnants, which implied the ballooning and bursting of the ISSC mucocele into both sides of the frontal sinus. The two different mechanisms of development of the ISSC mucoceles may vary in relation to the time of onset.


International Journal of Clinical Oncology | 2013

Early evaluation of neoadjuvant chemotherapy response using FDG-PET/CT predicts survival prognosis in patients with head and neck squamous cell carcinoma

Masahiro Kikuchi; Yuji Nakamoto; Shogo Shinohara; Keizo Fujiwara; Hiroshi Yamazaki; Yuji Kanazawa; Risa Kurihara; Ippei Kishimoto; Hiroyuki Harada; Yasushi Naito


Practica oto-rhino-laryngologica | 2013

Synchronous Multiple Malignancies in Patients with Head and Neck Squamous Cell Carcinoma

Risa Tona; Shogo Shinohara; Masahiro Kikuchi; Keizo Fujiwara; Hiroshi Yamazaki; Ippei Kishimoto; Hiroyuki Harada; Yasushi Naito


Journal of Japan Society for Head and Neck Surgery | 2013

A comparison of three methods to detect human papilloma virus in oropharyngeal carcinoma: PCR-invader, Hybrid Capture and p16 immunohistochemistry staining

Shogo Shinohara; Masahiro Kikuchi; Risa Tona; Yuji Kanazawa; Ippei Kishimoto; Hiroyuki Harada; Yukihiro Imai; Yu Usami


Nippon Jibiinkoka Gakkai Kaiho | 2011

Clinical evaluation of 24 cases of primary thyroid malignant lymphoma

Masahiro Kikuchi; Shogo Shinohara; Keizo Fujiwara; Hiroshi Yamazaki; Yuji Kanazawa; Risa Kurihara; Ippei Kishimoto; Hiroyuki Harada; Yasushi Naito


Toukeibu Gan | 2018

Three cases of external auditory canal cholesteatoma in patients after radiotherapy

Yasuhiro Kosaka; Masaki Kokubo; Shogo Shinohara; Shinji Takebayashi; Hiroyuki Harada


Annals of Clinical Otolaryngology | 2017

Clinical Image: Tophaceous Pseudogout of the Temporomandibular Joint

Shogo Shinohara; Toshihiko Takenobu; Kazuya Kataoka; Mika Ikeda; Hiroyuki Harada

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Hiroshi Yamazaki

Showa Pharmaceutical University

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