Hiroyuki Setoi

Total synthesis of (+)-castanospermine from D-mannose

Abstract A total synthesis of (+)-castanospermine (2) has been achieved starting from D-mannose by a route adopting a double-cyclization process (5c→6) as the key step.

Structure and total synthesis of chryscandin, a new antifungal antibiotic

Abstract The structure elucidation and total synthesis of chryscandin (1), a new antifungal antibiotic produced by Chrysosporium pannorum No.4629, is reported.

Deacylative condensation I. A new facile method for the direct α-methylenation of ester or lactone starting from monosubstituted active methylene compounds

Bei der Behandlung mit Lithium-diisopropylamid (LDA), Paraformaldehyd und nachfolgender Pyrolyse erhalt man aus den Acetessigestern (I) die α-substituierten Acrylsauren (II).

Stereocontrolled synthesis of conjugated dienamides via the ynamine-claisen rearrangement with (arylthio)ynamine

Abstract A new, versatile method for the stereocontrolled synthesis of conjugated (E, E)-dienamides is described which relies upon the acid-catalyzed or thermal ynamine-Claisen rearrangement with readily accessible (arylthio)ynamines.