Hiroyuki Shiojiri
Eisai
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Publication
Featured researches published by Hiroyuki Shiojiri.
Analytical Biochemistry | 1986
Hiromitsu Yokohama; Issei Ohtsuka; Hiroyuki Shiojiri; Kouich Katayama; Seiji Ishikawa
Abstract A high-performance liquid chromatographic method has been developed for the measurement of cholesterol 7α-hydroxylase activity in liver microsomes. 7α-Hydroxycholesterol generated from endogenous choleserol was derivatized with anthroyl 1-carbonitrile, chromatographed on a reversephase column, and detected fluorometrically. The detection limit of 7α-hydroxycholesterol was 1 ng/tube. The cholesterol 7α-hydroxylase activity in rat liver microsomes was assayed by this method, and the effects of some detergents and of the addition of exogenous cholesterol together with detergents on the enzyme activity were investigated. The endogenous 7α- and 7β-hydroxy-cholesterol could be also measured by this method.
Archive | 1981
Isao Yamatsu; Yuichi Inai; Shinya Abe; Hideaki Watanabe; Toshiji Igarashi; Hiroyuki Shiojiri; Yoshio Tanabe; Kuniko Hara
Archive | 1984
Isao Yamatsu; Yuichi Inai; Shinya Abe; Hideaki Watanabe; Toshiji Igarashi; Hiroyuki Shiojiri; Yoshio Tanabe; Kumiko Hara
Archive | 1986
Kouji Nakamoto; Takeshi Suzuki; Shinya Abe; Kenji Hayashi; Akiharu Kajiwara; Isao Yamatsu; Issei Otsuka; Hiroyuki Shiojiri
Archive | 1981
Isao Yamatsu; Yuichi Inai; Shinya Abe; Hideaki Watanabe; Toshiji Igarashi; Hiroyuki Shiojiri; Yoshio Tanabe; Kuniko Hara
Japanese Journal of Pharmacology | 1991
Takao Saeki; Issei Ohtsuka; Ryoichi Hashida; Hiroyuki Shiojiri; Isao Yamatsu; Nobuhiro Morisaki; Yasushi Saito
European Journal of Pharmacology | 1990
Takao Saeki; Hajime Tsunoda; Hiroyuki Shiojiri; Isao Yamatsu; Nobuhiro Morisaki; Yasushi Saito
Archive | 1986
Kouji Nakamoto; Takeshi Suzuki; Shinya Abe; Kenji Hayashi; Akiharu Kajiwara; Isao Yamatsu; Issei Otsuka; Hiroyuki Shiojiri
Archive | 1981
Isao Yamatsu; Yuichi Inai; Shinya Abe; Hideaki Watanabe; Toshiji Igarashi; Hiroyuki Shiojiri; Yoshio Tanabe; Kuniko Hara
Archive | 1981
Isao Yamatsu; Yuichi Inai; Shinya Abe; Hideaki Watanabe; Toshiji Igarashi; Hiroyuki Shiojiri; Yoshio Tanabe; Kuniko Hara
