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Dive into the research topics where Holger Birk is active.

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Featured researches published by Holger Birk.


Confocal, Multiphoton, and Nonlinear Microscopic Imaging (2003), paper 5139_147 | 2003

Advances in Multispectral Confocal Imaging

Holger Birk; Rafael Storz; Heinrich Ulrich

Due to the tendencies in biological research towards multiple stainings and increased use of newly developed dyes like fluorescent proteins, the application areas of multispectral confocal imaging increase rapidly. We present here the most recent advances in this technology particularily concerning but not limited to the excitation module, the detection module, and the beamsplitter optics of multispectral confocal microscopes.


Three-Dimensional and Multidimensional Microscopy: Image Acquisition and Processing IX | 2002

Programmable beam-splitter for confocal laser scanning microscopy

Holger Birk; Johann Engelhardt; Rafael Storz; Nicole Hartmann; Joachim Bradl; Heinrich Ulrich

In confocal microscopy manifold combinations of dyes are used. The entire wavelength range from near-ultraviolet to near-infrared is used to excite these dyes. Their emission is then detected primarily in the visible range. In addition to the number of dyes, the number of possible excitation laser lines is already large and constantly increasing. Due to the almost unlimited number of possible combinations, programmable devices are required. This is true for excitation-modules, beam-splitters and detection modules. Systems using filters with fixed spectral properties can practically fulfill the requirements for only a very small subset of applications. Programmable devices have been realized for excitation using Acousto Optical Tunable Filters (AOTFs). Freely definable spectral detectors are available for a perfect adaptation to the desired emission bands. The missing link for a completely filter-free design is now introduced using an Acousto Optical Beam Splitter (AOBS).


Archive | 2001

Illuminating device and microscope

Holger Birk; Rafael Storz


Archive | 2001

Entangled-photon microscope and confocal microscope

Holger Birk; Rafael Storz; Johann Engelhardt


Archive | 2003

Scanning microscope comprising a confocal slit scanner for imaging an object

Werner Knebel; Holger Birk; Rafael Storz


Archive | 2005

Arrangement for examining microscopic preparations with a scanning microscope, and illumination device for a scanning microscope

Holger Birk; Rafael Storz


Archive | 2001

Laser illuminator and method

Holger Birk; Rafael Storz; Johann Engelhardt; Kyra Moellmann


Archive | 2004

Method and instrument for microscopy

Holger Birk; Rafael Storz; Johann Engelhardt; Kyra Moellmann


Archive | 2001

Scanning microscope with multiband illumination and optical component for a scanning microscope with multiband illumination

Holger Birk; Rafael Storz; Johann Engelhardt


Archive | 2012

DEVICE AND METHOD FOR DETECTING LIGHT

Holger Birk

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Johann Engelhardt

German Cancer Research Center

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