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Howard J. Schaeffer

GlaxoSmithKline

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Publication

Featured researches published by Howard J. Schaeffer.

Journal of Medicinal Chemistry | 1974

Enzyme inhibitors. 26. Bridging hydrophobic and hydrophilic regions on adenosine deaminase with some 9-(2-hydroxy-3-alkyl)adenines

Howard J. Schaeffer; Charles F. Schwender

Journal of Medicinal Chemistry | 1988

Effect of acyclic pyrimidines related to 9-[(1,3-dihydroxy-2-propoxy)methyl]guanine on herpesviruses.

Lilia M. Beauchamp; Barbara L. Serling; John E. Kelsey; Karen K. Biron; Peter Collins; J. W. T. Selway; Jung-Chung Lin; Howard J. Schaeffer

Journal of Medicinal Chemistry | 1971

Novel substrate of adenosine deaminase.

Howard J. Schaeffer; S. Gurwara; Robert Vince; S. Bittner

Journal of Medicinal Chemistry | 1981

Pyrimidine acyclic nucleosides. 1-[(2-Hydroxyethoxy)methyl]pyrimidines as candidate antivirals

James L. Kelley; John E. Kelsey; William R. Hall; Mark P. Krochmal; Howard J. Schaeffer

Journal of Medicinal Chemistry | 1985

Modifications on the heterocyclic base of acyclovir: syntheses and antiviral properties.

Lilia M. Beauchamp; Bart L. Dolmatch; Howard J. Schaeffer; Peter Collins; D. J. Bauer; Paul M. Keller; James A. Fyfe

Journal of Medicinal Chemistry | 1965

Enzyme Inhibitors. IX. Hydrophobic Interactions of Some 9-Alkyladenines with Adenosine Deaminase1,2

Howard J. Schaeffer; David Vogel

Journal of Medicinal Chemistry | 1981

Pyrimidine acyclic nucleosides. 5-Substituted 1-[(2-aminoethoxy)methyl]uracils as candidate antivirals.

James L. Kelley; Mark P. Krochmal; Howard J. Schaeffer

Journal of Medicinal Chemistry | 1966

Enzyme inhibitors. 13. The synthesis of active-site-directed irreversible inhibitor of adenosine deaminase.

Howard J. Schaeffer; Eugene Odin

Journal of Medicinal Chemistry | 1981

Purine acyclic nucleosides. Nitrogen isosteres of 9-[(2-hydroxyethoxy)methyl]guanine as candidate antivirals.

James L. Kelley; Mark P. Krochmal; Howard J. Schaeffer

Journal of Medicinal Chemistry | 1970

Structure-activity relationships in adenosine deaminase inhibitors.

Howard J. Schaeffer; Roland Norman Johnson; Eugene Odin; Corwin Hansch

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Lilia M. Beauchamp

Research Triangle Park

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Thomas A. Krenitsky

Research Triangle Park

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Eugene Odin

University at Buffalo

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Mark P. Krochmal

GlaxoSmithKline

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James L. Kelley

Research Triangle Park

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Roland Norman Johnson

University at Buffalo

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Charles F. Schwender

University at Buffalo

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James A. Fyfe

Research Triangle Park

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Paulo de Miranda

Research Triangle Park

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Robert Vince

University of Minnesota

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