Huanyu Cheng
Pennsylvania State University
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Publication
Featured researches published by Huanyu Cheng.
Science | 2012
Suk Won Hwang; Hu Tao; Dae-Hyeong Kim; Huanyu Cheng; Jun Kyul Song; Elliott Rill; Mark A. Brenckle; Bruce Panilaitis; Sang Min Won; Yun Soung Kim; Young Min Song; Ki Jun Yu; Abid Ameen; Rui Li; Yewang Su; Miaomiao Yang; David L. Kaplan; Mitchell R. Zakin; Marvin J. Slepian; Yonggang Huang; Fiorenzo G. Omenetto; John A. Rogers
Reversible Implants Silicon electronics are generally designed to be stable and robust—it would be counterproductive if the key parts of your computer or cell phone slowly dissolved away while you were using it. In order to develop transient electronics for use as medical implants, Hwang et al. (p. 1640, see the cover) produced a complete set of tools and materials that would be needed to make standard devices. Devices were designed to have a specific lifetime, after which the component materials, such as porous silicon and silk, would be resorbed by the body. A platform of materials and fabrication methods furnishes resorbable electronic devices for in vivo use. A remarkable feature of modern silicon electronics is its ability to remain physically invariant, almost indefinitely for practical purposes. Although this characteristic is a hallmark of applications of integrated circuits that exist today, there might be opportunities for systems that offer the opposite behavior, such as implantable devices that function for medically useful time frames but then completely disappear via resorption by the body. We report a set of materials, manufacturing schemes, device components, and theoretical design tools for a silicon-based complementary metal oxide semiconductor (CMOS) technology that has this type of transient behavior, together with integrated sensors, actuators, power supply systems, and wireless control strategies. An implantable transient device that acts as a programmable nonantibiotic bacteriocide provides a system-level example.
Nature Materials | 2013
R. Chad Webb; Andrew P. Bonifas; Alex Behnaz; Yihui Zhang; Ki Jun Yu; Huanyu Cheng; Mingxing Shi; Zuguang Bian; Zhuangjian Liu; Yun Soung Kim; Woon Hong Yeo; Jae Suk Park; Jizhou Song; Yuhang Li; Yonggang Huang; Alexander M. Gorbach; John A. Rogers
Precision thermometry of the skin can, together with other measurements, provide clinically relevant information about cardiovascular health, cognitive state, malignancy and many other important aspects of human physiology. Here, we introduce an ultrathin, compliant skin-like sensor/actuator technology that can pliably laminate onto the epidermis to provide continuous, accurate thermal characterizations that are unavailable with other methods. Examples include non-invasive spatial mapping of skin temperature with millikelvin precision, and simultaneous quantitative assessment of tissue thermal conductivity. Such devices can also be implemented in ways that reveal the time-dynamic influence of blood flow and perfusion on these properties. Experimental and theoretical studies establish the underlying principles of operation, and define engineering guidelines for device design. Evaluation of subtle variations in skin temperature associated with mental activity, physical stimulation and vasoconstriction/dilation along with accurate determination of skin hydration through measurements of thermal conductivity represent some important operational examples.
Nature Communications | 2014
Jonathan A. Fan; Woon Hong Yeo; Yewang Su; Yoshiaki Hattori; Woosik Lee; Sung Young Jung; Yihui Zhang; Zhuangjian Liu; Huanyu Cheng; Leo Falgout; Mike Bajema; Todd P. Coleman; Daniel J. Gregoire; Ryan J. Larsen; Yonggang Huang; John A. Rogers
Stretchable electronics provide a foundation for applications that exceed the scope of conventional wafer and circuit board technologies due to their unique capacity to integrate with soft materials and curvilinear surfaces. The range of possibilities is predicated on the development of device architectures that simultaneously offer advanced electronic function and compliant mechanics. Here we report that thin films of hard electronic materials patterned in deterministic fractal motifs and bonded to elastomers enable unusual mechanics with important implications in stretchable device design. In particular, we demonstrate the utility of Peano, Greek cross, Vicsek and other fractal constructs to yield space-filling structures of electronic materials, including monocrystalline silicon, for electrophysiological sensors, precision monitors and actuators, and radio frequency antennas. These devices support conformal mounting on the skin and have unique properties such as invisibility under magnetic resonance imaging. The results suggest that fractal-based layouts represent important strategies for hard-soft materials integration.
Science | 2015
Sheng Xu; Zheng Yan; Kyung In Jang; Wen Huang; Haoran Fu; Jeonghyun Kim; Zijun Wei; Matthew Flavin; Joselle M. McCracken; Renhan Wang; Adina Badea; Yuhao Liu; Dongqing Xiao; Guoyan Zhou; Jung Woo Lee; Ha Uk Chung; Huanyu Cheng; Wen Ren; Anthony Banks; Xiuling Li; Ungyu Paik; Ralph G. Nuzzo; Yonggang Huang; Yihui Zhang; John A. Rogers
Popping materials and devices from 2D into 3D Curved, thin, flexible complex three-dimensional (3D) structures can be very hard to manufacture at small length scales. Xu et al. develop an ingenious design strategy for the microfabrication of complex geometric 3D mesostructures that derive from the out-of-plane buckling of an originally planar structural layout (see the Perspective by Ye and Tsukruk). Finite element analysis of the mechanics makes it possible to design the two 2D patterns, which is then attached to a previously strained substrate at a number of points. Relaxing of the substrate causes the patterned material to bend and buckle, leading to its 3D shape. Science, this issue p. 154; see also p. 130 Complex, three-dimensional shapes emerge via the geometric buckling of two-dimensional micro/nanostructures. [Also see Perspective by Ye and Tsukruk] Complex three-dimensional (3D) structures in biology (e.g., cytoskeletal webs, neural circuits, and vasculature networks) form naturally to provide essential functions in even the most basic forms of life. Compelling opportunities exist for analogous 3D architectures in human-made devices, but design options are constrained by existing capabilities in materials growth and assembly. We report routes to previously inaccessible classes of 3D constructs in advanced materials, including device-grade silicon. The schemes involve geometric transformation of 2D micro/nanostructures into extended 3D layouts by compressive buckling. Demonstrations include experimental and theoretical studies of more than 40 representative geometries, from single and multiple helices, toroids, and conical spirals to structures that resemble spherical baskets, cuboid cages, starbursts, flowers, scaffolds, fences, and frameworks, each with single- and/or multiple-level configurations.
Nano Letters | 2011
Rak Hwan Kim; Myung Ho Bae; Dae Gon Kim; Huanyu Cheng; Bong Hoon Kim; Dae-Hyeong Kim; Ming Li; Jian Wu; Frank Du; Hoon Sik Kim; Stanley Kim; David Estrada; Suck Won Hong; Yonggang Huang; Eric Pop; John A. Rogers
This paper describes the fabrication and design principles for using transparent graphene interconnects in stretchable arrays of microscale inorganic light emitting diodes (LEDs) on rubber substrates. We demonstrate several appealing properties of graphene for this purpose, including its ability to spontaneously conform to significant surface topography, in a manner that yields effective contacts even to deep, recessed device regions. Mechanics modeling reveals the fundamental aspects of this process, as well as the use of the same layers of graphene for interconnects designed to accommodate strains of 100% or more, in a completely reversible fashion. These attributes are compatible with conventional thin film processing and can yield high-performance devices in transparent layouts. Graphene interconnects possess attractive features for both existing and emerging applications of LEDs in information display, biomedical systems, and other environments.
Advanced Materials | 2013
Jae Woong Jeong; Woon Hong Yeo; Aadeel Akhtar; James J. S. Norton; Young Jin Kwack; Shuo Li; Sung Young Jung; Yewang Su; Woosik Lee; Jing Xia; Huanyu Cheng; Yonggang Huang; Woon Seop Choi; Timothy Bretl; John A. Rogers
Thin, soft, and elastic electronics with physical properties well matched to the epidermis can be conformally and robustly integrated with the skin. Materials and optimized designs for such devices are presented for surface electromyography (sEMG). The findings enable sEMG from wide ranging areas of the body. The measurements have quality sufficient for advanced forms of human-machine interface.
Nature Communications | 2014
Lizhi Xu; Sarah R. Gutbrod; Andrew P. Bonifas; Yewang Su; Matthew S. Sulkin; Nanshu Lu; Hyun-Joong Chung; Kyung In Jang; Zhuangjian Liu; Ming Ying; Chi Lu; R. Chad Webb; Jong Seon Kim; Jacob I. Laughner; Huanyu Cheng; Yuhao Liu; Abid Ameen; Jae Woong Jeong; Gwang Tae Kim; Yonggang Huang; Igor R. Efimov; John A. Rogers
Means for high-density multiparametric physiological mapping and stimulation are critically important in both basic and clinical cardiology. Current conformal electronic systems are essentially 2D sheets, which cannot cover the full epicardial surface or maintain reliable contact for chronic use without sutures or adhesives. Here we create 3D elastic membranes shaped precisely to match the epicardium of the heart via the use of 3D printing, as a platform for deformable arrays of multifunctional sensors, electronic and optoelectronic components. Such integumentary devices completely envelop the heart, in a form-fitting manner, and possess inherent elasticity, providing a mechanically stable biotic/abiotic interface during normal cardiac cycles. Component examples range from actuators for electrical, thermal and optical stimulation, to sensors for pH, temperature and mechanical strain. The semiconductor materials include silicon, gallium arsenide and gallium nitride, co-integrated with metals, metal oxides and polymers, to provide these and other operational capabilities. Ex vivo physiological experiments demonstrate various functions and methodological possibilities for cardiac research and therapy.
Nature | 2016
Seung-Kyun Kang; Rory K.J. Murphy; Suk Won Hwang; Seung Min Lee; Daniel V. Harburg; Neil A. Krueger; Jiho Shin; Paul Gamble; Huanyu Cheng; Sooyoun Yu; Zhuangjian Liu; Jordan G. McCall; Manu Stephen; Hanze Ying; Jeonghyun Kim; Gayoung Park; R. Chad Webb; Chi Hwan Lee; Sangjin Chung; Dae Seung Wie; Amit D. Gujar; Bharat Vemulapalli; Albert H. Kim; Kyung Mi Lee; Jianjun Cheng; Younggang Huang; Sang Hoon Lee; Paul V. Braun; Wilson Z. Ray; John A. Rogers
Many procedures in modern clinical medicine rely on the use of electronic implants in treating conditions that range from acute coronary events to traumatic injury. However, standard permanent electronic hardware acts as a nidus for infection: bacteria form biofilms along percutaneous wires, or seed haematogenously, with the potential to migrate within the body and to provoke immune-mediated pathological tissue reactions. The associated surgical retrieval procedures, meanwhile, subject patients to the distress associated with re-operation and expose them to additional complications. Here, we report materials, device architectures, integration strategies, and in vivo demonstrations in rats of implantable, multifunctional silicon sensors for the brain, for which all of the constituent materials naturally resorb via hydrolysis and/or metabolic action, eliminating the need for extraction. Continuous monitoring of intracranial pressure and temperature illustrates functionality essential to the treatment of traumatic brain injury; the measurement performance of our resorbable devices compares favourably with that of non-resorbable clinical standards. In our experiments, insulated percutaneous wires connect to an externally mounted, miniaturized wireless potentiostat for data transmission. In a separate set-up, we connect a sensor to an implanted (but only partially resorbable) data-communication system, proving the principle that there is no need for any percutaneous wiring. The devices can be adapted to sense fluid flow, motion, pH or thermal characteristics, in formats that are compatible with the body’s abdomen and extremities, as well as the deep brain, suggesting that the sensors might meet many needs in clinical medicine.
ACS Nano | 2012
Taeseup Song; Huanyu Cheng; Heechae Choi; Jin Hyon Lee; Hyungkyu Han; Dong Hyun Lee; Dong Su Yoo; Moon Seok Kwon; Jae Man Choi; Seok Gwang Doo; Hyuk Chang; Jianliang Xiao; Yonggang Huang; Won Il Park; Yong Chae Chung; Hansu Kim; John A. Rogers; Ungyu Paik
Problems related to tremendous volume changes associated with cycling and the low electron conductivity and ion diffusivity of Si represent major obstacles to its use in high-capacity anodes for lithium ion batteries. We have developed a group IVA based nanotube heterostructure array, consisting of a high-capacity Si inner layer and a highly conductive Ge outer layer, to yield both favorable mechanics and kinetics in battery applications. This type of Si/Ge double-layered nanotube array electrode exhibits improved electrochemical performances over the analogous homogeneous Si system, including stable capacity retention (85% after 50 cycles) and doubled capacity at a 3C rate. These results stem from reduced maximum hoop strain in the nanotubes, supported by theoretical mechanics modeling, and lowered activation energy barrier for Li diffusion. This electrode technology creates opportunities in the development of group IVA nanotube heterostructures for next generation lithium ion batteries.
Small | 2013
Canan Dagdeviren; Suk Won Hwang; Yewang Su; Stanley Kim; Huanyu Cheng; Onur Gur; Ryan Haney; Fiorenzo G. Omenetto; Yonggang Huang; John A. Rogers
The combined use of ZnO, Mg, MgO, and silk provides routes to classes of thin-film transistors and mechanical energy harvesters that are soluble in water and biofluids. Experimental and theoretical studies of the operational aspects and dissolution properties of this type of transient electronics technology illustrate its various capabilities. Application opportunities range from resorbable biomedical implants, to environmentally dissolvable sensors, and degradable consumer electronics.