Hui-Ming Hua

Sg17-1-4, a Novel Isocoumarin from a Marine Fungus Alternaria tenuis Sg17-1

One novel isocoumarin, named Sg17-1-4, along with two known isocoumarins AI-77-B and AI-77-F were obtained from a marine fungus Alternaria tenuis Sg17-1. Their structures were elucidated based on detailed NMR analysis. The cytotoxicities of these compounds were evaluated in vitro.

One new anthraquinone from marine Streptomyces sp. FX-58

One new anthraquinone, 1,8-dihydroxy-2-ethyl-3-methylanthraquinone (1), together with two known compounds octadecanoic acid (2) and cholest-4-en-3-one (3) was isolated from marine actinomycete Streptomyces sp. FX-58. The structure of 1 was elucidated on the basis of spectroscopic methods, especially, the 2D-NMR spectral analysis. The cytotoxic activities of 1 were evaluated in vitro.

Two diketopiperazines from marine fungus Gliocladium sp. YUP08

Two new diketopiperazines, PJ147 (1) and PJ157 (2), were isolated from the mycelium of a fungus, Gliocladium sp. YUP08, which was separated from sea mud collected in Rushan, Shandong, China. Their structures were elucidated by spectroscopical and chemical methods.

One new cinnamic imide dervative from the fruits of Tribulus terrestris

One new cinnamic imide derivative, named tribulusimide C (1), was isolated from the fruits of Tribulus terrestris, together with three known compounds, N-p-coumaroyltyramine (2), terrestriamide (3), N-trans-caffeoyltyramine (4). The structure of 1 was elucidated based on chemical analysis and spectral methods (IR, 1D and 2D NMR, HR-FAB-MS, EI-MS).

Chemical constituents of Stellera chamaejasme L.

A new biflavanone, 7-methoxyneochamaejasmin A, and a new chromone derivative, isomohsenone, were isolated from the roots of Stellera chamaejasme L. The structures of two compounds were determined by means of ESI-MS, 1H NMR and 13C NMR, especially 2D NMR spectral analyses.

A new tannin-related compound from the rhizome of Polygonum bistorta L.

A new tannin-related compound named bistortaside A (1) and a known compound have been isolated from the rhizome of Polygonum bistorta L. A new compound was elucidated as 3-methyl-gallic acid 4-O-β-d-(6′-O-3″-methyl-galloyl)-glucopyranoside and a known compound was quercetin-3′-O-β-d-glucopyranoside (2) on the basis of spectroscopic analysis.

Aldose Reductase Inhibitors from Stellera chamaejasme

Abstract Six biflavonoids (chamaejasmin, 7-methoxyneochamaejasmin, 7-methoxychamaejasmin, chamaejasmenin B, chamaechromone, wikstrol A) from Stellera chamaejasme. L. have been assayed to show good aldose reductase inhibiting activity. These compounds may be useful to improve diabetic complications such as neuropathy, cataract formation, neophropathy, and retinopathy.

Biflavonoids from Stellera chamaejasme

Five biflavonoids (wilstrol A, wikstrol B, neochamaejasmin A, neochamaejasmin B and chamajssmine) were isolated from the roots of Stellera chamaejasme L. These compounds play a very important role in the chemotaxonomy of Thymelaeaceae.

A new monoterpene from the bark of Eucommia ulmoides

A new monoterpene, eucommidiol ( 1 ), was isolated from the bark of Eucommia ulmoides Oliv. (Eucommiaceae), together with a known compound 1,4a,5,7a-tetrahydro-7-hydroxymethyl-cyclopenta[c]pyran-4-carboxylic methyl ester. The structure of 1 was characterized as 6,6a-di(hydroxymethyl)-3,3a,4,6a-tetrahydro-2H-cyclopenta[b]furan-2-one on the basis of chemical and spectral evidence including 2DNMR studies.

Platyphyllin A, a novel coumarone from the leaves of Betula platyphylla Suk.

Abstract A novel coumarone, platyphyllin A (1), was isolated from the leaves of Betula platyphylla Suk‥ The structure elucidation was accomplished by the analysis of spectroscopic data. Compound 1 was identified as a new coumarone skeleton, which was first isolated from plants.