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Dive into the research topics where Hülya Gürbüz is active.

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Featured researches published by Hülya Gürbüz.


Clinical and Experimental Hypertension | 2010

Endothelial nitric oxide synthase immunreactivity and the ultrastructure of endothelial cells of umbilical artery in normal and preeclamptic pregnancies.

Mehmet Kanter; Hülya Gürbüz; Tulay Kilic Okman

Our objective was to investigate the endothelial nitric oxide synthase (eNOS) immuno-reactivity and the ultrastructure of endothelial cells of a human umbilical artery in both normal and preeclamptic pregnancies. The umbilical cords from normal and preeclamptic pregnancies were collected immediately after vaginal and abdominal deliveries. Umbilical arteries were isolated and fixed in 10% neutral formaline solution, embedded in paraffin, and then stained with hematoxylin and eosin (H&E) for the histologic investigation, and eNOS activation were examined in samples by streptavidine-biotine immunohistochemical methods. The arterial sections were also fixed in phosphate-buffered 2.5% glutaraldehyde solution (pH 7.2) for 3 h and post-fixed with 1% osmium tetroxide at 4°C for 2 h for the investigation of the ultrastructural examination. In the umbilical artery of preeclamptic pregnancies, endothelial cells were oval, triangular, or polygonal, and were disorganized. Some endothelial cells were separated by enlarged intercellular spaces. A dilated endoplasmic reticulum, swollen mitochondria, and vanished mitochondrial cristae were observed. The nuclei of some endothelial cells displayed deep invaginations and irregular outlines. Most endothelial cells had a high number of cytoplasmic vacuoles. In preeclampsia, eNOS immunoreactivity increased considerably in endothelial cells when compared to normal pregnancies. We believe that preeclampsia plays an important role in the pathogenesis of endothelial cell dysfunction and activation in the umbilical artery. However, the disturbance mechanism of endothelial cells is not known, and further studies are necessary to clarify the exact mechanism.


Saudi Medical Journal | 2006

The synovial plicae in the knee joint.

Hülya Gürbüz; Osman U. Calpur; Mert Özcan; Tunc Kutoglu; Recep Mesut


Clinical Anatomy | 2005

The extensor indicis et medii communis.

Bulent Yalcin; Tunc Kutoglu; Hasan Ozan; Hülya Gürbüz


Turkiye Klinikleri Journal of Medical Ethics-Law and History | 2004

Kadavra Bağışı Üzerine Görüşler

Hülya Gürbüz; Esin Karlikaya; Recep Mesut


Balkan Medical Journal | 2014

Kolda Brakiyalis Kasından Köken Alan Biseps Kasının Aksesuvar Başı: Olgu Sunumu

Ali Yılmaz; Oğuz Taşkınalp; Hülya Gürbüz


Archive | 2007

Lateral Ulnar Kollateral ve Anuler Ligamanlar›n Anatomik Boyutlar›

Hülya Gürbüz; Tunç Kuto; Recep Mesut; Mert Özcan


Balkan Medical Journal | 2007

Anatomical Dimensions of Lateral Ulnar Collateral and Annular Ligaments

Hülya Gürbüz; Tunç Kutoğlu; Recep Mesut; Osman U. Calpur; Mert Özcan


Archive | 2005

Original Contribution A CASE OF THE SUBCLAVIUS POSTICUS MUSCLE

Tunc Kutoglu; Enis Ulucam; Hülya Gürbüz


Balkan Medical Journal | 2005

The Accessory Head of the Biceps Brachii Muscle Originating From the Brachialis Muscle: A Case Report

Ali Yılmaz; Oğuz Taşkınalp; Hülya Gürbüz


Balkan Medical Journal | 2004

The Vascular System of the Liver

Hülya Gürbüz

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Bulent Yalcin

Military Medical Academy

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Hasan Ozan

Military Medical Academy

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