Hülya Nazik

Sporadic and familial cases of aquagenic keratoderma

BACKGROUND Aquagenic keratoderma is a dermatosis characterized by transient whitish and transluscent hyperwrinkling after water exposure. The aim of the current report was to present a sporadic and familial cases of aquagenic keratoderma. OBSERVATION Sporadic Case: A 38-year-old female patient presented with eruption in the right hand after exposure to water. The patient was placed on systemic acitretin therapy with the diagnosis of idiopathic acquired aquagenic keratoderma. No recurrence occurred during a 6-month follow-up period. Familial Cases: A 55-year-old male patient, who was engaged in fishery, presented to the outpatient clinics of the department of dermatology due to whitish vesicles in the palms of both hands. It was realized that the father, sister, and brother of the patient had similar complaints. The cases were thought to have familial aquagenic keratoderma; however acitretin therapy could not be initiated due to elevated alanine aminotransferase and triglyceride levels. Topical application of salicylic acid 10% and 10% urea containing lotions was effective but did not prevent recurrence. CONCLUSION Systemic acitretin may be an effective agent in the treatment of aquagenic keratoderma, and topical application of 10% salicylic acid and 10% urea-containing lotion did not prevent recurrence.

Evaluation Of Self-Care Power In Leprosy Patients

1Kahramanmaraş Sütçü İmam Üniversitesi Tıp Fakültesi, Dermatoloji AD, Kahramanmaraş, Türkiye 2Elazığ Eğitim ve Araştırma Hastanesi, Dermatoloji Kliniği, Elazığ, Türkiye 3Elazığ Eğitim ve Araştırma Hastanesi, Göz Kliniği, Elazığ, Türkiye 4Kahramanmaraş Sütçü İmam Üniversitesi Tıp Fakültesi, Enfeksiyon Hastalıkları ve Klinik Mikrobiyoloji AD, Kahramanmaraş, Türkiye 5Kahramanmaraş Sütçü İmam Üniversitesi Tıp Fakültesi, Halk Sağlığı AD, Kahramanmaraş, Türkiye 6Fırat Üniversitesi Tıp Fakültesi, Dermatoloji AD, Elazığ, Türkiye

Effect of onychomycosis on pulse oximeter

Objective Onychomycosis causes nail thickness and discoloration of the dorsum of the nail plate. This study was aimed to investigate the effect of discoloration and nail thickness associated with onychomycosis on pulse oximetry measurement. Materials and methods The involvement degree of onychomycosis was determined using onychomycosis severity index (OSI). Two different measurements were recorded by pulse oximetry. The first one was from the nail with onychomycosis, and the second one was from the normal nail of the same hand. Results A total of 93 onychomycosis cases were included in the study. When SpO2 values of white nail color were measured, it was statistically significant higher in the onychomycosis group than the control (P<0.001). On the contrary, in the yellow nail, SpO2 values were lower in the onychomycosis group (P<0.001). Similarly in the brown nail, SpO2 values were lower in the onychomycosis group, but there was no statistically significance (P=0.083). It was determined that there was no statistically significant difference between SpO2 values and OSI (P=0.563). Conclusion As a result, SpO2 values were affected by discoloration owing to onychomycosis. SpO2 values were found lower in patients with moderate and severe OSI, which is related to nail thickness than the control. It was concluded that the discoloration and nail thickness associated with onychomycosis were effective on pulse oximetry measurement.

Results of intravenous immunoglobulin use and treatment in the South Province of Turkey

Objective In this study, we aimed to evaluate the use of intravenous immunoglobulin (IVIG) in our clinic and investigate the effect of its treatment on diseases in patients with pemphigus. Materials and methods Age, sex, disease, skin biopsy result, duration of illness, treatments received, IVIG adverse effects, and clinical course were recorded by screening medical records of patients with different diagnoses receiving IVIG. The findings were evaluated retrospectively. Findings The total number of cases treated with IVIG was 21. A total of 14 cases were diagnosed as having pemphigus, and three cases were diagnosed as having pyoderma gangrenosum, one (4.8%) case as Sweet syndrome, one (4.8%) case as lichen planus, one (4.8%) case as resistant urticaria, and one (4.8%) case as hyperimmunoglobulin E syndrome. The mean time to start IVIG treatment from diagnosis in patients with pemphigus was 2.62±2.3 years (minimum–maximum: 1–10 years). The mean number of cure IVIG treatment cycles given to patients was 11.38±7.63 (minimum–maximum: 1–30). In patients with pemphigus, a partial remission was achieved with an average cure IVIG treatment cycle of 2.71±3.3 (minimum–maximum: 0–10 cures). In three (21.4%) of the pemphigus cases that received IVIG, the treatment was terminated owing to remission. In pemphigus cases where the treatment was terminated owing to remission, the mean number of IVIG cycles was 12.7±5.9 (minimum–maximum: 6–17). Conclusion IVIG treatment has become a reliable treatment option in our clinic, which is preferred owing to successful treatment results and clinical experience in many different diseases, especially pemphigus.

Activity Criteria in Behçet’s Disease

Behçet’s disease is a complex disease characterized by remission and activation periods of unknown duration. It has an unpredictable course. Behçet’s disease shows a heteroge‐ neous pattern of organ involvement that occurs in recurrent episodes of acute inflamma‐ tion throughout the course of the disease. Disease activity in Behçet’s disease is difficult to define because of its fluctuating course, lack of laboratory tests reflecting overall dis‐ ease activity, absence of a standardized form to report the severity of Behcet’s disease manifestations and also trying to develop new diagnostic criteria. This led to the devel‐ opment of standardized disease activity index. To be useful, a measurement of disease activity must be valid, reliable, and simple enough to use in routine clinical practice. We will try to explain what the situation is in terms of Behçet’s disease activity index.

Heart-rate recovery index in patients with chronic idiopathic urticaria

Received: 10.07.2017 Accepted: 29.08.2017 1Zonguldak Atatürk State Hospital, Department of Cardiology, Zonguldak, Turkey 2Kayseri Educational And Research Hospital, Departmant of Cardiology, Kayseri, Turkey 3Elazığ Educational Research Hospital, Department of Dermatology, Elazig, Turkey 4Kahramanmaraş Sütçü Imam Universty Mediccal Faculty, Department of Dermatology, Kahramanmaraş, Turkey Yazışma adresi: Emine Altuntas, Zonguldak Atatürk State Hospital, Department of Cardiology, Zonguldak, Turkey e-mail: emine_altuntas@hotmail.com INTRODUCTION