Hümeyra Kocaelli

iNOS Expression in Oral and Gastrointestinal Tract Mucosa

It is known that the overproduction of nitric oxide (NO) by nitric oxide synthase (NOS) occurs during the progression of various inflammatory diseases in intestinal tract. NOS inhibitors or inducible nitric oxide synthase (iNOS) gene expression inhibitors should be considered as potential anti-inflammatory agents, as NO synthesized by iNOS is related to various pathophysiological processes including inflammation. In order to understand the relationship between iNOS and pathological reactions such as the inflammatory process and malign transformation clearly, the existence and amount of constitutive expression should be determined. It is crucial to comprehend the harmful and protective amounts of iNOS expressions in order to clarify the relationship between iNOS and pathological processes. Evidently, only after this inspection is it possible to utilize iNOS as a marker and treatment instrument during the diagnosis and treatment of malign transformation and the inflammatory process.

ALZHEIMER HASTALIĞI VE DENTAL YAKLAŞIM ALZHEIMER'S DISEASE AND DENTAL MANAGEMENT

Ozet¬: Alzheimer hastaligi kisinin hafiza, ogrenme, karar verme, iletisim kurma, gunluk aktivitelerini yerine getirme gibi yeteneklerinde yavas ve ilerleyici hasar yaratan kortikal dejeneratif bir beyin hastaligidir. Bilissel ve motor fonksiyonlarda meydana gelen bozulma, kisinin yeterli agiz hijyeni uygulamalarini yerine getirmesine, agri yada disfonksiyon gibi rahatsizliklarini dile getirmesine engel olur. Bu hastalarda yasam boyu agiz sagliginin devamliliginin saglanabilmesi icin duzenli dental bakim sarttir. Hastaliga sahip bireyler icin, her bir bireyin ihtiyaclarina uygun tedavi seceneklerini belirlemek son derece hassas ve uzerinde onemle durulmasi gereken bir konudur. Bu derleme calismasi Alzheimer hastaliginin nedenleri, epidemiyolojisi, teshis ve dental tedavi stratejilerini ozetlemektedir. Anahtar kelimeler: Alzheimer hastaligi, dental, agiz hijyeni. Summary: Alzheimers disease is a cortical, degenerative, progressive brain disorder that gradually destroys a persons memory and ability to learn, make judgments, communicate and carry out daily activities. Cognitive and motor deficits may led difficulties to perform adequate oral hygiene and communicate discomforts such as pain or dysfunction. To maintain lifelong good oral health in this patients, regular dental care is a necessity. The most critical point is to sepecify the individual treatment needs for Alzheimers patients. This review summarizes the causes, epidemiology diagnosis, and dental management of Alzheimers disease. Key words: Alzheimers disease, dental, oral hygiene

TRAVMATİK DİŞ YARALANMALARINDA SPLİNT UYGULAMALARI SPLINT APPLICATIONS IN TRAUMATIC INJURIES OF THE TEETH

OZET Dis ve cevre dokularin maruz kaldigi travmalar sonucu olusan yaralanmalarda eger diste bir yer degistirme olduysa normal fonksiyon ve iyilesme, disin yerine yerlestirilmesini takiben splint uygulamasi sayesinde gerceklesebilmektedir. Splintleme, travmaya ugramis dislerin tedavisinde ve periodontal dokularin iyilesmesindeki en onemli basamaklardan biridir. Bu derlemede, cesitli splint tipleri ve splintleme tekniklerinin yani sira farkli travmatik yaralanmalardaki splintleme surelerinden ve dokudaki etkilerinden bahsedilmistir. Anahtar Kelimeler: Splint, Travma, Splint Uygulamalari. ABSTRACT Following traumatic injuries of the teeth and the periradicular tissues, normal function may be regained and healing may occur , if the displaced tooth is stabilized by splint application. Splinting is one of the crucial factors in the treatment of traumatized teeth and periodontal tissues. In this review, various splint types and splinting techniques are explained. Moreover, splinting periods used in different traumatic injuries and the effect of this procedure on tissues are discussed. Key Words: Splint, Trauma, Splint Applications.