Hüseyin Badem

What is harmful for male fertility: Cell phone or the wireless internet?

In this study, we aimed to assess the potential harmful effects of radiofrequency‐electromagnetic radiation on sperm parameters. We requested semen for analyses from the male patients coming to our infertility division and also asked them to fill out an anonymous questionnaire. We queried their mobile phone and wireless internet usage frequencies in order to determine their radiofrequency‐electromagnetic radiation exposure. A total of 1082 patients filled the questionnaire but 51 of them were excluded from the study because of azoospermia. There was no significant difference between sperm counts and sperm morphology excluding sperm motility, due to mobile phone usage period, (p = 0.074, p = 0.909, and p = 0.05, respectively). The total motile sperm count and the progressive motile sperm count decreased due to the increase of internet usage (p = 0.032 and p = 0.033, respectively). In line with the total motile sperm count, progressive motile sperm count also decreased with wireless internet usage compared with the wired internet connection usage (p = 0.009 and p = 0.018, respectively). There was a negative correlation between wireless internet usage duration and the total sperm count (r = −0.089, p = 0.039). We have also explored the negative effect of wireless internet use on sperm motility according to our preliminary results.

Melatonin protects kidney against apoptosis induced by acute unilateral ureteral obstruction in rats.

Introduction To investigate whether there was a protective effect of melatonin on apoptotic mechanisms after an acute unilateral obstruction of the kidney. Material and methods A total of 25 rats consisting of five groups were used in the study, designated as follows: Group 1: control, Group 2: sham, Group 3: unilateral ureteral obstruction treated with only saline, Group 4: unilateral ureteral obstruction treated with melatonin immediately, and Group 5: unilateral obstruction treated with melatonin one day after obstruction. Melatonin was administered as a 10 mg/kg dose intraperitoneally. The kidneys were evaluated according to the apoptotic index and Ki-67 scores. Results Comparison of all obstruction groups (Group 3, 4, and 5), revealed that the apoptotic index was significantly higher in Groups 1 and 2. Despite melatonin reduced apoptotic mechanisms in Groups 4 and 5, there was no significant difference between Groups 4 and 5 in terms of the reduction of apoptosis. However, the reduction of apoptosis in the melatonin treated group did not decrease to the level of Groups 1 and 2. Conclusions Despite melatonin administration, which significantly reduces the apoptotic index occurring after acute unilateral ureteral obstruction, the present study did not observe a return to normal renal histology in the obstruction groups.

The comparison of the influence between two different bowel preparation methods on sepsis after prostate biopsies

Introduction Transrectal ultrasonography (TRUS) guided prostate needle biopsy has been performed to diagnose and stage prostate cancer for many years. There are many different bowel preparation protocols to diminish the infectious complications, but there is no standardized consensus among urologists. Therefore, we aimed to assess two different bowel preparation methods on the rate of infectious complications in patients who underwent TRUS–guided prostate biopsy. Material and methods A total of 387 cases of TRUS–guided prostate biopsy were included in this retrospective study. All patients received antibiotic prophylaxis with ciprofloxacin (500 mg) twice a day orally for 7 days starting on the day before the biopsy. The patients were divided into two groups according to the bowel preparation method used. Patients (Group 1, n = 164) only received self–administrated phosphate enema) on the morning of the prostate biopsy. Other patients (Group 2, n = 223) received sennasoid a–b laxatives the night before the prostate biopsy. Infectious complications were classified as sepsis, fever (greater than 38°C) without sepsis, and other clinical infections. Results Major complications developed in 14 cases (3.8%), including 3 cases (0.8%) of urinary retention, and 11 (3%) infectious complications, all of which were sepsis. There were 3 and 8 cases of urosepsis in Group 1 and Group 2, respectively. There were no statistically significant differences between both Groups regarding to the rates of urosepsis (p = 0.358). Conclusions Despite both methods of bowel preparation, sodium phosphate enema or sennasoid a–b calcium laxatives, before TRUS–guided prostate biopsy have similar effect on the rate of urosepsis, so both methods of bowel preparation can be safely used.

Progresif spermatik kanal parakordomasının vücudun farklı kısımlarına bir yıl içinde tekrarlayan metastazları: Nadir bir olgu

Parachordoma is a rare entity with an unknown origin, which reported nearly in 60 cases. We are reporting an aggressive tumor that has two recurrences in 5 months in different sites. A 49 year old male admitted with right inguinal pain that underwent a computed tomography, revealed a 52x50 mm tumor at the right inguinal subepidermal region. After the resection, pathology of the mass was parachordoma. Four months after the operation, patient admitted with a solitary mass in the right testis. Ultrasonography revealed four different masses in the right inguinal and right testicular region. Second pathology results were also parachordoma. One month later the second operation, patient again admitted to hospital with right hip pain, had a solitary mass on the collum femoris in the magnetic resonance imaging consulted for radiotherapy. Parachordoma is a rare, benign entity that must be closely followed up. The physician must be aware of the malignancy especially in the first year with existence of recurrence and metastasis. Radiotherapy is recommended after maximal resection of tumor especially in metastatic cases. J Clin Exp Invest 2013; 4 (3): 377-379