Hyuma Makizako
RMIT University
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Featured researches published by Hyuma Makizako.
Geriatrics & Gerontology International | 2009
Hyuma Makizako; Tsutomu Abe; Hiroyuki Shimada; Takeshi Ohnuma; Taketo Furuna; Yoshio Nakamura
Background: It is argued that a multidimensional approach is necessary for burden assessment. Reducing caregiver burden is a social problem in the ageing Japan society. We examined the combined effect of factors affecting the care burden among community‐dwelling handicapped people and their caregivers.
Journal of Nutrition Health & Aging | 2018
Takehiko Doi; Hyuma Makizako; Kota Tsutsumimoto; Ryo Hotta; Sho Nakakubo; Keitaro Makino; Takao Suzuki; Hiroyuki Shimada
ObjectivesFrailty is a course experienced in advanced aging. Identification of a biological factor associated with frailty is required. Although serum insulin-like growth factor-1 (IGF-1) is a potential factor related with frailty, consensus has not been reached regarding this relationship. This study aimed to investigate the association between IGF-1 and frailty in older adults.DesignCross-sectional study.SettingCohort study that was part of the “National Center for Geriatrics and Gerontology–Study of Geriatric Syndromes.”ParticipantsThe study participants were 4133 older adults (mean age, 71.8 ± 5.4 years).MeasurementsWe assessed serum IGF-1 levels and frailty status and collected demographic variables, including cognitive function, as covariates.ResultsFrailty and pre-frailty were present in 274 subjects (7%) and 1930 subjects (47%), respectively. Subjects were divided into four groups based on quartiles of IGF-1 levels. Multinomial logistic analysis showed that the lowest group had significant odds of pre-frailty (crude model: odds ratio [OR] 1.58, 95% confidence interval [CI] 1.30–1.90, p <.001; adjusted model: OR 1.38, 95% CI 1.13–1.68, p =.002) and frailty (crude model: OR 3.42, 95% CI 2.38-4.92, p <.001; adjusted model: OR 1.54, 95% CI 1.02–2.32, p =.039), compared with the highest group.ConclusionLower serum IGF-1 levels were independently related with frailty in older adults.
Maturitas | 2018
Seongryu Bae; Sangyoon Lee; Sungchul Lee; Kazuhiro Harada; Hyuma Makizako; Hyuntae Park; Hiroyuki Shimada
BACKGROUND We used longitudinal cohort data to investigate whether hearing problems and low levels of social activity lead to a higher incidence of disability among community-dwelling older adults. METHODS Participants were 4576 older adults (47.8% male, mean age 75.9 years) who met the study inclusion criteria. Longitudinal data on the incidence of disability were monitored monthly. Disability was defined as Japanese long-term care insurance certification for personal support or care for 2 years following the baseline assessment. Hearing problems were measured using the Hearing Handicap Inventory for the Elderly and for Adults - Screening version. Participants completed a questionnaire that included five questions on daily social activities. RESULTS In the adjusted model that included potential covariates, participants with co-occurring hearing problems and low participation rates in social activities were at higher risk of developing a disability than participants without hearing problems and low levels of social activity (hazard ratio [HR] = 2.13, 95% confidence interval [CI]: 1.31-3.45). The second highest risk of developing a disability was found for those with low levels of social activity alone (HR = 1.98, 95% CI: 1.26-3.11), and the third highest for those with hearing problems alone (HR = 1.38, 95% CI: 1.07-1.77). CONCLUSIONS Hearing problems and a lack of social activity were independent risk factors for developing a disability. Co-occurring hearing problems and low levels of participation in social activities represented the largest risk factor for disability.
Journal of Nutrition Health & Aging | 2018
Sho Nakakubo; Hyuma Makizako; Takehiko Doi; Kota Tsutsumimoto; Ryo Hotta; Sungchul Lee; Seongryu Bae; Keitaro Makino; Takao Suzuki; Hiroyuki Shimada
ObjectiveThe objective of this study was to investigate whether older adults who have a particularly long sleep duration are likely to exhibit physical frailty, similar to those with a particularly short sleep duration.DesignCross-sectional study.SettingThe National Center for Geriatrics and Gerontology – Study of Geriatric Syndromes.ParticipantsA total of 9,824 older adults (mean age: 73.6 ± 5.5 years, 4,812 men and 5,012 women) met the entry criteria for this study.MeasurementsWe divided the participants into three groups according to self-reported sleep duration (Short: ≤ 6 h, Mid: 6.1–8.9 h (control), Long: ≥ 9 h). Physical frailty was characterized based on the criteria from the Cardiovascular Health Study. Multinomial logistic regression analysis was performed to evaluate the effect of sleep duration on physical frailty by sex.ResultsAmong all participants, the prevalence of physical frailty was higher in the Short (10.5%) and Long (17.9%) groups than in the Mid (7.4%) group (p < 0.001). Multinomial logistic regression analysis showed that both Short and Long groups had a significantly higher odds ratio (OR) for physical frailty than the Mid group [Short: OR 1.53, 95% confidence interval (CI) 1.26–1.87; Long: OR 2.39, 95% CI 1.90–3.00], even after adjusting for age, educational level, number of medications, body mass index, Mini Mental State Examination score, current smoking and alcohol habits, self-perceived health, and medical history.ConclusionBoth long and short sleep durations were associated with physical frailty. Further studies are required to confirm the effect of sleep duration on the incidence or worsening of physical frailty in older adults.
Journal of Cachexia, Sarcopenia and Muscle | 2018
Kota Tsutsumimoto; Takehiko Doi; Hyuma Makizako; Ryo Hotta; Sho Nakakubo; Keitaro Makino; Takao Suzuki; Hiroyuki Shimada
Anorexia of ageing may be a precursor to various geriatric syndromes. We elucidated whether anorexia of ageing had a significant impact on incident disability and investigated whether anorexia of ageing had a direct association with future disability or an indirect association with disability via frailty.
International Journal of Geriatric Psychiatry | 2018
Kazuki Uemura; Hyuma Makizako; Sangyoon Lee; Takehiko Doi; Songchul Lee; Kota Tsutsumimoto; Hiroyuki Shimada
It remains unclear what kinds of behavior prevent the development of geriatric depression. This study aimed to elucidate behavioral predictors of increased depressive symptoms in older adults focusing on gender differences.
Geriatrics & Gerontology International | 2018
Ryo Hotta; Hyuma Makizako; Takehiko Doi; Kota Tsutsumimoto; Sho Nakakubo; Keitaro Makino; Hiroyuki Shimada
To examine the relationship between cognitive function and unsafe driving acts among community‐dwelling older adults with cognitive impairments.
Geriatrics & Gerontology International | 2018
Sungchul Lee; Sangyoon Lee; Seongryu Bae; Kazuhiro Harada; Songee Jung; Masakazu Imaoka; Hyuma Makizako; Takehiko Doi; Hiroyuki Shimada
To evaluate the relationship between kidney function without diabetes and components of the frailty phenotype in community‐dwelling Japanese older adults.
Geriatrics & Gerontology International | 2018
Takehiko Doi; Hyuma Makizako; Kota Tsutsumimoto; Sho Nakakubo; Minji Kim; Satoshi Kurita; Ryo Hotta; Hiroyuki Shimada
The purpose of the present study was to identify risk factors for physical frailty and to understand the transitional status of frailty.
Geriatrics & Gerontology International | 2018
Hiroyuki Shimada; Hyuma Makizako; Sangyoon Lee; Takehiko Doi; Sungchul Lee
The prevalence of dementia is rising due to increases in the aging population and chronic health conditions. The present study examined whether lifestyle activities, including instrumental activities of daily living and social roles, were associated with dementia incidence in Japanese community‐dwelling older adults.