Hyun-Koo Yoon
Kwandong University
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Publication
Featured researches published by Hyun-Koo Yoon.
Journal of Clinical Pharmacy and Therapeutics | 2008
So Young Park; Y. S. Kang; M. S. Jeong; Hyun-Koo Yoon; Ki-Ok Han
Background and objective: CYP3A, the drug‐metabolizing enzyme is an important factor in the pharmacokinetics of many drugs. Polymorphism of the CYP3A5 gene is known to influence the functionality of the CYP3A5 enzymes. The full extent of CYP3A5 genetic polymorphism was analysed in a Korean population.
Clinical Endocrinology | 2011
Ho-Yeon Chung; Sang Ouk Chin; Moo-Il Kang; Jung-Min Koh; Sung-Hwan Moon; Byung-Koo Yoon; Hyun-Koo Yoon; Yoon-Sok Chung; Hyoung-Moo Park
Background We performed a randomized, double‐blind, prospective, 16‐week clinical trial to evaluate the efficacy and safety of risedronate with and without cholecalciferol on 25‐hydroxyvitamin D [25(OH)D] levels and bone markers in Korean patients with osteoporosis.
Journal of Bone and Mineral Metabolism | 2012
Hyung Jin Choi; Chan Soo Shin; Yong-Chan Ha; Sunmee Jang; Suhyun Jang; Chanmi Park; Hyun-Koo Yoon; Seongsu Lee
An error occurred in the second sentence of the abstract regarding the name of HIRA institution. The correct name is ‘‘Health Insurance Review and Assessment Service’’ instead of ‘‘Health Insurance Review Agency’’. There are errors in the name of authors. The correct names are ‘‘Sunmee Jang’’, ‘‘Suhyun Jang’’ and ‘‘Chanmi Park’’, instead of ‘‘Sun-Mee Jang’’, ‘‘Su-Hyung Jang’’ and ‘‘Chan Mi Park’’, respectively.
Clinical Interventions in Aging | 2013
Ho Yeon Chung; Jawon Koo; Su Kyoung Kwon; Moo-Il Kang; Seong-Hwan Moon; Jin-Young Park; Chan Soo Shin; Byung-Koo Yoon; Hyun-Koo Yoon; Jae-Suk Chang; Yoon-Sok Chung; Hyoung-Moo Park
Purpose This study investigated the efficacy and safety of monthly risedronate, with and without cholecalciferol, on 25-hydroxyvitamin D (25[OH]D) levels and bone markers in Korean patients with osteoporosis. Methods A randomized, double-blinded, prospective, 16-week clinical trial was conducted in ten hospitals. A total of 150 subjects with osteoporosis were randomized to one of the two treatment groups: RSDM+ (monthly risedronate 150 mg and cholecalciferol 30,000 IU combined in a single pill, n = 74) or RSDM (monthly risedronate 150 mg alone, n = 76). We measured serum levels of 25-hydroxyvitamin D (25[OH]D), parathyroid hormone (PTH), and bone markers, as well as performing muscle-function tests at baseline and after 16 weeks of treatment. Results After 16 weeks, serum 25(OH)D levels significantly increased from 17.8 to 26.8 ng/mL in the RSDM+ group, but did not change in the RSDM group. The RSDM+ group exhibited significantly decreased serum PTH from 46 to 36.7 pg/mL, while the RSDM group showed a tendency for PTH to increase from 38 to 40.6 pg/mL. In both groups, serum bone-specific alkaline phosphatase and C-terminal telopeptide rapidly declined, with significance at 16 weeks; there were no significant differences between the groups. Conclusion A once-monthly pill of risedronate and cholecalciferol provided equivalent antiresorptive efficacy to risedronate alone in terms of bone turnover and improved 25(OH)D levels over the 16-week treatment period without significant adverse events in Korean patients with osteoporosis.
Journal of Bone and Mineral Metabolism | 2011
Chanmi Park; Yong-Chan Ha; Sunmee Jang; Suhyun Jang; Hyun-Koo Yoon; Young-Kyun Lee
Journal of Bone and Mineral Metabolism | 2012
Hyung Jin Choi; Chan Soo Shin; Yong-Chan Ha; Sunmee Jang; Suhyun Jang; Chan Mi Park; Hyun-Koo Yoon; Seongsu Lee
Journal of Nutritional Science and Vitaminology | 2014
Sunmin Park; Hyun-Koo Yoon; Hyun-Mee Ryu; You Jung Han; Si Won Lee; Bo Kyung Park; So-Young Park; Chang Hoon Yim; Sunghoon Kim
Bone | 2011
Deog-Yoon Kim; Yong-Keun Lee; Yong-Chan Ha; Jae Suk Chang; S.-M. Jang; Hyun-Koo Yoon
Calcified Tissue International | 2009
Yoon-Sok Chung; Sung-Kil Lim; Ho-Yeon Chung; In-Kyu Lee; Il-Hyung Park; Ghi-Su Kim; Yong-Ki Min; Moo-Il Kang; Dong-Jin Chung; Yong-Ki Kim; Woong Hwan Choi; Min Ho Shong; Ji-Hyun Park; Dong Won Byun; Hyun-Koo Yoon; Chan Soo Shin; Yil-Seob Lee; Namhee Kwon
The Journal of the Korean Hip Society | 2010
Chanmi Park; Sunmee Jang; Suhyun Jang; Yong-Chan Ha; Young-Kyun Lee; Hyun-Koo Yoon; Chan Soo Shin; Deog-Yoon Kim; Seongsu Lee; Hyung Jin Choi; Bom-Taeck Kim; Ji-Yeob Choi