Hyung Wook Noh

Photoacoustic imaging probe for detecting lymph nodes and spreading of cancer at various depths

Abstract. We propose a compact and easy to use photoacoustic imaging (PAI) probe structure using a single strand of optical fiber and a beam combiner doubly reflecting acoustic waves for convenient detection of lymph nodes and cancers. Conventional PAI probes have difficulty detecting lymph nodes just beneath the skin or simultaneously investigating lymph nodes located in shallow as well as deep regions from skin without any supplementary material because the light and acoustic beams are intersecting obliquely in the probe. To overcome the limitations and improve their convenience, we propose a probe structure in which the illuminated light beam axis coincides with the axis of the ultrasound. The developed PAI probe was able to simultaneously achieve a wide range of images positioned from shallow to deep regions without the use of any supplementary material. Moreover, the proposed probe had low transmission losses for the light and acoustic beams. Therefore, the proposed PAI probe will be useful to easily detect lymph nodes and cancers in real clinical fields.

Sequential algorithm for the detection of the shockable rhythms in electrocardiogram

We suggest a sequential algorithm for the detection of the ventricular fibrillation (VF) and ventricular tachycardia (VT) of a rate above 180 bpm, so called shockable rhythms. The built-in algorithm for ECG analysis embedded in the portable bio-signal sensing module is aimed to discriminate between shockable and non-shockable rhythms and its accuracy is analyzed. An algorithm for VF/VT detection is proposed to analyze every 1 s ECG episode using the past 8 s episodes. The method is tested with 844,587 ECG episodes from the widely accepted databases. A sensitivity of 86.8 % and a specificity of 99.4 % were obtained and compared with the previous results.

Development of a patch type embedded cardiac function monitoring system using dual microprocessor for arrhythmia detection in heart disease patient

A patch type embedded cardiac function monitoring system was developed to detect arrhythmias such as PVC (Premature Ventricular Contraction), pause, ventricular fibrillation, and tachy/bradycardia. The overall system is composed of a main module including a dual processor and a Bluetooth telecommunication module. The dual microprocessor strategy minimizes power consumption and size, and guarantees the resources of embedded software programs. The developed software was verified with standard DB, and showed good performance.

A basic study for patch type ambulatory 3-electrode ECG monitoring system for the analysis of acceleration signal and the limb leads and augmented unipolar limb leads signal

A compact and portable device was designed for preliminary study of patch type ambulatory 3-electrode ECG monitoring system for limb leads and augmented unipolar limb leads signal analysis. The developed system also can measure and send the acceleration signals wirelessly during daily life to analyze the users information. The 3-electrode system is feasible to provide the information of limb leads and augmented unipolar limb leads for further arrhythmia analysis and simultaneously shows lots of issues to be more broadly applicable and more powerful device.

MOPA fiber laser for photoacoustic imaging using arrayed ultrasound transducer

An Nd:YAG laser is generally used as the optical source for photoacoustic imaging (PAI) systems, which support a high-power pulsed laser. However, PAI systems based on Nd:YAG lasers have several disadvantages, such as instability against impact and vibration, poor mobility, and large size. To overcome the limitations, we demonstrate a PAI system using a master oscillator power amplifier (MOPA) fiber laser and an arrayed ultrasound transducer. The fabricated MOPA fiber laser has a variable repetition rate in the range of 1–50 kHz, a pulse width of 10–70 ns, and an output power of 160 μJ. Furthermore, it is stable to impact and vibration, mobile, and compact with a size of 427×250×170 mm3. We achieved PAI 150 times faster using MOPA fiber laser than using Nd:YAG laser with the arrayed ultrasound transducer composed of 128 elements. Therefore, we believe that the PAI system based on the MOPA fiber laser has significant potential for use as a clinical ultrasound imaging system.

A basic study of activity type detection and energy expenditure estimation for children and youth in daily life using 3-axis accelerometer and 3-stage cascaded artificial neural network.

It is important to prevent obesity in childhood given that many obese adults have been obese since childhood. An activity monitor could provide an effective aid in preventing obesity if it records not only the calorie assessment but also activity detection to check how active a child is in daily life. The current study is for activity monitoring algorithm and we designed 3-stage cascaded artificial neural network. To develop the algorithm, we recruited 76 participants, made 3-axis accelerometer for them, and acquired activity data and calorie consumption data through them. Finally, we designed 3-stage cascaded network to classify the activities and to assess energy consumption. The 3-stage network classifies 4 activities of walking, running, stairs moving, and jumping rope with overall accuracy of 94.70%, and predicts calorie consumption with average accuracy of 81.91%, which is better than the results of the 2-stage network. Future work would include the enhancement of the network performance.

A preliminary study of the effect of electrode placement in order to define a suitable location for two electrodes and obtain sufficiently reliable ECG signals when monitoring with wireless system

Most countries face high and increasing rates of cardiovascular disease. Each year, heart disease kills more Americans than cancer. Therefore, there has been a promising market for portable ECG equipment and it is increasing. To use portable ECG measuring devices, it is essential to define a suitable location for the measuring as we need to reduced electrode size and distance. This research proposes to study how the inter-electrode distance affects the signal and how the electrode pair should be placed on the chest in order to obtain a sufficiently reliable ECG signal to detect heart arrhythmias in any environment, such as home or work. Therefore, we developed a compact, portable patch type ambulatory ECG monitoring system, Heart Tracker, using a microprocessor for preliminary study of signal analysis. To optimize the electrode arrangement in wireless environment, we compared HT and standard 12 lead with changing electrode position.